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Hematology

Image: The SpectraMax M Series multimode microplate reader (Photo courtesy of Molecular Devices).

Multiple Sclerosis Associated with Leaked Hemoglobin in Brain

In multiple sclerosis (MS), progressive disease develops in over half of those who present with an initial relapsing phase, known as secondary progressive MS (SPMS), but can also present as primary progressive MS (PPMS). More...
05 Jan 2017
Image: A photomicrograph of bone marrow aspirate from a patient with multiple myeloma, showing numerous plasma cells, which can be recognized by the eccentric nucleus and perinuclear halo (Photo courtesy of Dr. Michael G. Bayerl).

Prognostic Tool Identified for Newly Diagnosed Multiple Myeloma

The bone marrow (BM) microenvironment contains numerous cell types, including immunosuppressive tumor-associated macrophages (TAM), that promote the growth and survival of multiple myeloma (MM) cells. More...
29 Dec 2016
Image: The nCounter Analysis System is a novel digital read-out technology that provides direct multiplexed measurement of gene expression with high levels of precision and sensitivity (Photo courtesy of NanoString Technologies).

Stem Cell-Based Test Predicts Leukemia Patients' Response to Therapy

A 17-gene signature derived from leukemia stem cells has been developed that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment. More...
22 Dec 2016
Image: The XN-10 RET automated hematology system (Photo courtesy of Sysmex).

Increased Mean Corpuscular Hemoglobin Concentration Scrutinized for Accuracy

In daily practice in hematology laboratories, spurious increased mean corpuscular hemoglobin concentration (MCHC) induces an analytical alarm and needs prompt corrective action to ensure delivery of the right results to the clinicians. More...
21 Dec 2016
Image: The portable ClotChip will undergo clinical trials to further assess its ability to rapidly measure blood clotting at point-of-care with accuracy comparable to laboratory testing (Photo courtesy of Case Western Reserve University).

Novel Device May Provide Rapid POC Assessment of Clot Ability

Researchers have developed a sensor that, on initial testing, accurately assessed blood-clotting ability 95 times faster than current methods, which uses only a single drop of blood. The device also provided more information than existing approaches. More...
13 Dec 2016
Image: A stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia (Photo courtesy of VashiDonsk).

Genetic Testing Identifies High-Risk Subtype of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is less common in adults than in children, but adults are far less likely to survive. Adults make up about 40% of the estimated 6,590 new cases of ALL identified annually in the USA. More...
09 Dec 2016
Image: The UniCel DxH 800 Coulter Cellular Analysis System (Photo courtesy of Beckman Coulter).

Lab Tests Discriminate Bacterial from Nonbacterial COPD Exacerbations

The discrimination of bacterial from nonbacterial acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is difficult, causing antibiotics overuse and bacterial resistance. Sputum cultures are of limited use because results take time. More...
08 Dec 2016
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.