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Hematology

Image: Bone marrow biopsy of a patient with multiple myeloma, showing diffuse infiltration by neoplastic plasma cells, which can be recognized by the eccentric nucleus and perinuclear halo (Photo courtesy of Dr. Michael G. Bayerl).

Multiple Myeloma Survival Associated with Enzyme Levels

Multiple myeloma (MM) is the second most common blood cancer in the USA and 30% to 50% of multiple myeloma patients have extra copies of the gene that encodes the enzyme Adenosine Deaminase, RNA Specific (ADAR1). More...
21 Dec 2017
Image: A scanning electron micrograph (SEM) of induced stem cells (Photo courtesy of University of New South Wales).

Harvesting Method Produces Superior Transplantation Stem Cells

Hematopoietic stem cell transplantation is a potential curative therapy for malignant and nonmalignant diseases. Improving the efficiency of stem cell collection and the quality of the cells acquired can broaden the donor pool and improve patient outcomes. More...
19 Dec 2017
Image: Peripheral bloods smear showing five eosinophils, from a patient with eosinophilia (Photo courtesy of the Hospital for Sick Children, Toronto).

Eosinophilic Biomarker Found for Aggressive IBD

Peripheral blood eosinophilia (PBE) in inflammatory bowel disease is associated with ulcerative colitis (UC) and active disease. Little data exist on the long-term impact of PBE on disease course. More...
14 Dec 2017
Image: A diagram of the Kompetitive Allele Specific Polymerase Chain Reaction (PCR KASP) method (Photo courtesy of J.P. Livingstone).

Genetic Link Found Between Immune System and Lymphoma

Classical Hodgkin lymphoma (cHL) is a lymphoid malignancy of germinal center (GC) B-cell origin, which is characterized by Hodgkin and Reed–Sternberg (HRS) cells with a dominant background population of reactive inflammatory cells. More...
12 Dec 2017
Image: A stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia (Photo courtesy of VashiDonsk).

Missing DNA Fragments Could Predict Leukemia Relapse

A new risk scoring system has been developed for children with leukemia based on missing DNA fragments or 'microdeletions'. The risk score will allow doctors to better predict the chance of relapse of a subgroup of children currently hidden in a lower risk group. More...
11 Dec 2017
Image: A bone marrow aspirate from a patient with acute myeloid leukemia (Photo courtesy of Cytogenetic Oncology Laboratory).

HLF-Gene Controls Generation of Immune System

Blood stem cells give rise to all of the blood cells, the red blood cells that transport oxygen, the platelets that enable blood coagulation, and our immune cells that protect us from infections. More...
06 Dec 2017
Image: A hospitalized patient receiving a blood transfusion (Photo courtesy of the US National Institute of Health).

High-Value Practice Reduces Wasteful Blood Transfusions

Although blood transfusion is a lifesaving therapy for some patients, transfusion has been named one of the top five overused procedures in hospitals in the USA. More...
05 Dec 2017
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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