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Molecular Diagnostics

Image: Drops of blood on filter paper, easy to store for future diagnostics (Photo courtesy of Jan Björkeste, Uppsala University).

Blood Sample Storage Evaluated for PEA Analysis

A team of Swedish researchers evaluated and optimized conditions for storing samples of dried blood for current and future proximity extension assay (PEA) analysis. More...
29 May 2017

Metabolic Approach Helps Determine Risk of AD

Measurement of metabolites in saliva samples has been suggested as a noninvasive approach for determining risk of developing Alzheimer's disease. More...
29 May 2017

Alzheimer’s Disease Progression Predicted by Gene Mutation

Alzheimer's disease is the most common form of dementia in older adults. It is a degenerative condition, characterized by a steady loss of memory and a reduced ability to carry out daily activities. Today, an estimated five million people in the USA are living with the disease. More...
25 May 2017
Image: E. coli (shown here growing on an agar plate) is three-fold more common in advanced NAFLD patients than early stage patients, according to a recent study (Photo courtesy of the University of California San Diego School of Medicine / J. Craig Venter Institute).

Pathogens Help Diagnose Fatty Liver Disease

Nonalcoholic fatty liver disease is a condition characterized by a buildup of fat in the liver and the condition is often not detected until it is well advanced, and a definitive diagnosis requires an invasive biopsy of the liver. More...
25 May 2017
Image: Endometriosis in the peritoneal tissue (left) forming a scar. Under microscopy, it is composed of glands and surrounding stroma with chronic inflammation and fibrosis (Photo courtesy of Ie-Ming Shih).

Gene Sequencing Reveals Mutations in Endometriosis

Endometriosis occurs when tissue lining the uterus forms and grows outside of the organ, most often into the abdomen. The disease occurs in up to 10% of women before menopause and half of those with abdominal pain and infertility problems. More...
24 May 2017
Image: Technology that can detect the length of telomeres could hold the key to predicting the survival of patients with two types of blood cancer (Photo courtesy of Cardiff University).

Molecular Test Predicts Blood Cancer Patient Survival

Technology that can detect the length of small DNA structures in cancer cells could hold the key to predicting the outcome of patients with two different types of blood cancer. The test, used in conjunction with current methods, may help doctors make better choices about the most appropriate and effective treatment option for individual patients. More...
24 May 2017
Image: Human prostate specific antigen (PSA) with bound substrate forms complex with antibody (Photo courtesy of Wikimedia Commons).

Solvent Interaction Analysis of PSA Reduces Need for Biopsies

A novel test for serum levels of prostate specific antigen (PSA) was found to be better than currently available assays in distinguishing cancer from benign conditions, and identifying patients with high-risk disease. More...
22 May 2017
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