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Molecular Diagnostics

Image: A technical breakthrough for DNA imaging has been achieved that should quicken diagnosis of diseases for which analysis of DNA from single-cells is critical, such as early stage cancers and various pre-natal conditions (Photo courtesy of McGill University and Génome Québec Innovation Center).

Breakthrough DNA Analysis Technology to Hasten Problem Diagnosis

Researchers have achieved a technical breakthrough that should result in speedier diagnosis of diseases for which analysis of DNA from single-cells is critical, such as early stage cancers and various prenatal conditions.   More...
25 Aug 2014
Image: The Q700 microsonicator (Photo courtesy of Qsonica).

Urinary Biomarker Discovered in Variant Creutzfeldt-Jakob Disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease has been detected in the urine of patients with the disease.  More...
20 Aug 2014
Image: Histopathology of non-comedo breast intraductal carcinoma showing distended duct with intact basement membrane, micropapillary, and early cribriform growth pattern (Photo courtesy of Dr. Rachel Swart, MD, PhD).

New Gene Tied to Major Breast Cancer Risk

Clinical testing for genes that confer a predisposition to breast cancer has been revolutionized by next-generation sequencing and multigene panels that allow relatively inexpensive and rapid genetic profiling are now in widespread use.   More...
20 Aug 2014
Image: Histopathology of high-grade serous ovarian carcinoma (Photo courtesy of Dr. Ed Uthman, MD).

Effective Prognostic Marker Identified for Ovarian Cancer

High-grade serous ovarian carcinoma is the most prevalent of epithelial ovarian cancers and remains poorly understood due to a lack of biomarkers identified for clinical use, for diagnosis, or for prognosis of patient survival rates.  More...
20 Aug 2014
Image: Histopathology of clear cell renal cell carcinoma (Photo courtesy of Nephron).

Multigene Assay Predicts Cancer Patient's Survival

Patients with clear cell renal cell carcinoma have divergent survival outcomes and therapeutic responses, which may be determined by underlying molecular diversity.  More...
19 Aug 2014
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Potential Biomarker Identified for Alzheimer's Disease

A genome-wide association study has been conducted on family-based cohorts using an approach that accounts for family structure and calculates a risk score for Alzheimer's Disease as the outcome.  More...
18 Aug 2014
Image: The NanoDrop 2000 Spectrophotometer (Photo courtesy of Thermo Scientific).

Small RNAs in Blood May Reveal Heart Injury

An increase in certain micro ribonucleic acids circulating in the blood are linked with injury to cardiac muscle and these molecules might provide the basis for a more sensitive diagnostic tool than those currently available.  More...
14 Aug 2014
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