Molecular Diagnostics
![Image: Illustration depicts a healthy liver (left) and a liver with cirrhosis (Photo courtesy of [U.S.] National Institute of Diabetes and Digestive and Kidney Diseases)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2020-07-08/GMS-083B.jpg "Image: Illustration depicts a healthy liver (left) and a liver with cirrhosis (Photo courtesy of [U.S.] National Institute of Diabetes and Digestive and Kidney Diseases)"){kind=small}
Gut Microbiome Metabolomic Profiles Are Diagnostic for Liver Diseases
Liver disease researchers have developed a noninvasive method to diagnose nonalcoholic fatty liver disease (NAFLD) and predict progression to cirrhosis by analyzing metabolomic profiles produced by the microorganisms living in the gut (the microbiome). More...08 Jul 2020
DNA Sequencing Technique Unravels Genetic Diversity of Cancer Tumors
The ability to sequence the genome of a tumor has revolutionized cancer treatment by identifying drivers of cancer at the molecular level. However, understanding the genetic diversity of individual cells within a tumor and how that might impact the disease progression has remained a challenge, due to the current limitations of genomic sequencing. More...07 Jul 2020
An Eight MicroRNA Biomarker Panel for Diagnosis of ALS
A team of neurodegenerative disease researchers has identified eight microRNA sequences from enriched exosome extractions of blood plasma that consistently and significantly differentiate patients with amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) from healthy controls. More...07 Jul 2020
RNA Sequencing as Alternative to Immunohistochemistry in Cancer Diagnostics
The conventionally used method for cancer diagnostics relies on immunohistochemical dyeing of tumor tissue sections. It allows detecting the presence and measuring the concentration of marker proteins characterizing malignant growths. The resulting microscope images indicate whether the tumor is malignant and what its molecular type is. This information is crucial for selecting the right therapy. More...06 Jul 2020
Precision Medicine-Based Genetic Testing Developed for Prostate Cancer
Germline testing (GT) is a central feature of prostate cancer (PCA) treatment, management, and hereditary cancer assessment. Critical needs include optimized multigene testing strategies that incorporate evolving genetic data, consistency in GT indications and management, and alternate genetic evaluation models that address the rising demand for genetic services. More...01 Jul 2020
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Saliva-Based Assay Developed for HPV-Driven Oropharyngeal Cancer
Changes in Bacterial Load and Serum Cytokine Levels Predict Likelihood of Dying from Sepsis
Serum MicroRNAs Predict Likelihood of Pregnant Women Developing Pre-Eclampsia
Elevated Plasma Neurofilament Light Chain Predicts Worsening of Muscular Sclerosis Symptoms
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Representative Tumor Sampling Method Lessens Molecular Analyses Bias
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
