Molecular Diagnostics

Genetic Changes Identified in Patients Who Progress to Esophageal Cancer
Barrett’s esophagus (BE), a predominantly benign metaplasia that arises in the esophagus in response to chronic gastric reflux, also develops somatic mutations, but can further evolve extensive genomic alterations which confer significantly increased risk of progression to esophageal adenocarcinoma (ESAD). More...03 May 2022

Troponin Blood Test Offers Quick Method for Monitoring Patients after Cardiac Surgery
Validating a method with which to predict heart surgery patients most at risk is a big win. A large international study has now identified a first ever marker that is fast and reliable for the monitoring of patients after cardiac surgery. More...03 May 2022

Lipid Profiling of Blood Samples Reveals Biomarkers for Cardiometabolic Disease Risk
A lipidomics-based analysis of plasma samples from a large cohort of participants identified several lipids associated with cardiometabolic disease risk that might serve as biomarkers for diagnosis of cardiovascular disease and Type II diabetes. More...29 Apr 2022


Duplex ddPCR Assay Evaluated for Salmonella and Shigella
Bacteria of the genus Salmonella and Shigella are important pathogens of infectious diarrhea. Salmonellosis was the second most commonly reported gastrointestinal infection in humans in the European Union in 2018. Shigella spp was the second leading cause of mortality caused by diarrhea among all ages in 2016 globally, accounting for 212,438 deaths. More...28 Apr 2022

Glycosylated Serum Proteins Are Biomarkers for Severity of Liver Fibrosis
A recently developed assay was used to measure changes in the N-linked glycans on IgG subtypes in the blood, which can serve as surrogate markers of liver disease and may be able to replace the gold standard method, liver biopsy. More...28 Apr 2022

Automated Nucleic Acid Extraction/Superfast PCR Platform to Enable Analysis of POC PCR Tests in Minutes
An automated nucleic acid extraction/superfast PCR platform for the Point-of-Care testing (POCT) market could enable POC PCR tests to be analyzed in just minutes in doctor's offices, laboratories, and hospitals. More...28 Apr 2022
In Other News
Seegene Unveils World's First Commercialized '3 Ct' PCR Assay
Paper-Based Sensor Could Pave Way for Bedside Therapeutic Drug Monitoring System
Immunohistochemistry-Guided Sequencing Finds Mutations in Most Cortisol-Producing Adenomas
Blood Test Differentiates Severe COVID-19 from Preeclampsia in Pregnant Women
Pediatric Acute Lymphoblastic Leukemia Monitored by DNA Sequencing
Positive Blood Culture Processing Technology Accelerates Infection Identification and AST
Urine Test for Bladder Cancer Could Reduce Need for Invasive Cystoscopies
Rapid Virus Test Delivers Lab Quality Results within 30 Minutes
Blood Test Identifies Those at High Risk of Developing Human Tuberculosis
NfL Blood Test to Aid Prognosis and Treatment of Multiple Sclerosis
RNA-Based Noninvasive Gut Tests Enable Early Colorectal Cancer Screening
Blood Plasma Biomarker May Facilitate Rapid Diagnosis of Early-Stage Alzheimer’s Disease
New BD Assay Speeds Discovery in Autoimmune Disorders, Immuno-Oncology, and Infectious Diseases
Testing for Protein in Blood Receives More Support as Biomarker for Brain Disorders
Blood Test to Diagnose Skin Cancer May Help Avoid Invasive Skin Biopsies
Tumor Suppressor Adenomatous Polyposis Coli Regulates T Lymphocyte Migration
A Novel Small RNA Biomarker for Early Liver Cancer Diagnosis
NGS Technology-Based Assay Detects Minimal Residual Disease in Patients with Lymphatic Hematological Tumors
World’s First Rapid Oral Cancer Test to Revolutionize Diagnosis and Treatment
Broad Gene Panel Diagnoses Patients With Kidney Disease
Single-Cell RNA-Seq Reveals Cell Type–Specific Molecular and Genetic Associations to Lupus
Lyo-Ready PCR Reagents Make Ultra-Sensitive Diagnostics Development Painless
Smartphone-Powered Microfluidic ‘Lab on a Strip’ Dengue Test More Powerful Than LFT Testing
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.