Molecular Diagnostics

Duplex ddPCR Assay Evaluated for Salmonella and Shigella
Bacteria of the genus Salmonella and Shigella are important pathogens of infectious diarrhea. Salmonellosis was the second most commonly reported gastrointestinal infection in humans in the European Union in 2018. Shigella spp was the second leading cause of mortality caused by diarrhea among all ages in 2016 globally, accounting for 212,438 deaths. More...28 Apr 2022

Glycosylated Serum Proteins Are Biomarkers for Severity of Liver Fibrosis
A recently developed assay was used to measure changes in the N-linked glycans on IgG subtypes in the blood, which can serve as surrogate markers of liver disease and may be able to replace the gold standard method, liver biopsy. More...28 Apr 2022

Automated Nucleic Acid Extraction/Superfast PCR Platform to Enable Analysis of POC PCR Tests in Minutes
An automated nucleic acid extraction/superfast PCR platform for the Point-of-Care testing (POCT) market could enable POC PCR tests to be analyzed in just minutes in doctor's offices, laboratories, and hospitals. More...28 Apr 2022

Seegene Unveils World's First Commercialized '3 Ct' PCR Assay
Seegene, Inc. (Seoul, Korea) has developed the world's first commercialized PCR assay applying '3 Ct' technology which can provide the Ct value of three targets in one channel without compromising sensitivity and specificity. More...28 Apr 2022

Paper-Based Sensor Could Pave Way for Bedside Therapeutic Drug Monitoring System
A new paper-based sensor to identify Theophylline (THO) is not only easy to use but also economical and can reduce the burden of drug analysis in developing countries. Additionally, its prototype can be used to develop a bedside therapeutic drug monitoring system. More...27 Apr 2022

Immunohistochemistry-Guided Sequencing Finds Mutations in Most Cortisol-Producing Adenomas
Cushing syndrome (CS) represents a constellation of signs and symptoms associated with chronic and excessive exposure to glucocorticoids, from either endogenous endocrinopathies or, more commonly, from exogenous pharmacologic sources. More...27 Apr 2022

Blood Test Differentiates Severe COVID-19 from Preeclampsia in Pregnant Women
A new study has identified indicators which enable differentiating between preeclampsia and severe COVID-19 in pregnant women , thus paving the way for a more accurate diagnosis for both diseases and a better risk assessment. More...27 Apr 2022
In Other News
Pediatric Acute Lymphoblastic Leukemia Monitored by DNA Sequencing
Positive Blood Culture Processing Technology Accelerates Infection Identification and AST
Urine Test for Bladder Cancer Could Reduce Need for Invasive Cystoscopies
Rapid Virus Test Delivers Lab Quality Results within 30 Minutes
Blood Test Identifies Those at High Risk of Developing Human Tuberculosis
NfL Blood Test to Aid Prognosis and Treatment of Multiple Sclerosis
RNA-Based Noninvasive Gut Tests Enable Early Colorectal Cancer Screening
Blood Plasma Biomarker May Facilitate Rapid Diagnosis of Early-Stage Alzheimer’s Disease
New BD Assay Speeds Discovery in Autoimmune Disorders, Immuno-Oncology, and Infectious Diseases
Testing for Protein in Blood Receives More Support as Biomarker for Brain Disorders
Blood Test to Diagnose Skin Cancer May Help Avoid Invasive Skin Biopsies
Tumor Suppressor Adenomatous Polyposis Coli Regulates T Lymphocyte Migration
A Novel Small RNA Biomarker for Early Liver Cancer Diagnosis
NGS Technology-Based Assay Detects Minimal Residual Disease in Patients with Lymphatic Hematological Tumors
World’s First Rapid Oral Cancer Test to Revolutionize Diagnosis and Treatment
Broad Gene Panel Diagnoses Patients With Kidney Disease
Single-Cell RNA-Seq Reveals Cell Type–Specific Molecular and Genetic Associations to Lupus
Lyo-Ready PCR Reagents Make Ultra-Sensitive Diagnostics Development Painless
Smartphone-Powered Microfluidic ‘Lab on a Strip’ Dengue Test More Powerful Than LFT Testing
Single-Cell RNA Sequencing Identifies Mechanisms Underlying Autoimmune Diseases
Cervicovaginal DNA Virome Alterations Associated with Genital Inflammation
High-Throughput Screening Assay Identifies Drugs to Treat Resistant Prostate Cancer
Circulating Levels of Anti-Müllerian Hormone Can Identify Premenopausal Women Prior to Significant Bone Density Loss
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.