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Molecular Diagnostics

Image: New cervical screening test could predict cell changes years before they occur (Photo courtesy of Pexels)

Swab Test Identifies Dangerous Cervical Cell Changes Years Before They Occur

Researchers have developed a new swab test that identifies potentially dangerous cervical cell changes up to four years before they happen. More...
21 Oct 2022
Image: A rapid test for gum disease could aid in early detection of heart or lung disease, and diabetes (Photo courtesy of Pexels)

Periodontal Rapid Diagnostic Test Could Calculate Risk for Heart and Lung Disease

Researchers developing a rapid test for gum disease expect the technology - a probe for use in point of care settings such as dental surgeries or pharmacies - to play a pivotal role in early detection of heart or lung disease, type 2 diabetes and rheumatoid arthritis. More...
21 Oct 2022
Image: Blood test for pregnant women uses AI to diagnose congenital heart defects (Photo courtesy of Pexels)

AI-Based Prenatal Blood Test Identifies Dangerous Fetal Heart Defects before Birth

A new blood test for pregnant women uses artificial intelligence (AI) and genetic-related biomarkers to accurately detect, fetal congenital heart defects, well before birth. More...
19 Oct 2022
Image: The BenchMark ULTRA system is Roche Tissue Diagnostics’ most innovative, fully-automated immunohistochemistry and in situ hybridization slide staining system (Photo courtesy of Roche Group)

Gene Expression Profiling of Mucinous Ovarian Tumors Identifies Prognosis Markers

Advanced stage mucinous ovarian tumors have poor chemotherapy response and prognosis and lack biomarkers to aid Stage I adjuvant treatment. Differentiating primary mucinous ovarian carcinoma (MOC) from gastrointestinal (GI) metastases to the ovary is also challenging due to phenotypic similarities. More...
18 Oct 2022
Image: The T100 thermal cycler is a small thermal cycler offering a comprehensive set of convenient features in a small footprint (Photo courtesy of Bio-Rad)

Link Identified Between Mitochondria and Pancreatic Cancer Risk

Tumors invariably rewire their metabolism to promote cellular plasticity, adapt to ever-changing nutrient availability and acquire traits of aggressive disease, including metastatic competence. Cancer metabolism has long been equated with the preferential utilization of glycolysis by tumor cells even when oxygen is present. More...
18 Oct 2022
Image: The ambient nucleic acid amplification technology can bring CRISPR-based diagnostics into low-resource settings (Photo courtesy of Sherlock)

Nucleic Acid Amplification Technology to Help Develop Instrument-Free Assays

A new ambient amplification method could introduce an unprecedented robustness into molecular detection assays because it enables maximum amplification without heat-activation and in a range of temperatures, opening up various opportunities for point-of-need testing in different temperature and geographical settings. More...
18 Oct 2022
Image: FIT has been found to detect early-stage cancer at one-fifth the cost (Photo courtesy of Allegheny Health)

Fecal Immunochemical Test a Less Expensive Alternative for Colorectal Cancer Screening

A new study has revealed that a fecal immunochemical test (FIT) costs about one-fifth of a multi-target stool DNA test. These results align with previous studies out of Japan and the Netherlands examining FIT as an appropriate screening modality that is more cost effective than other types of noninvasive colorectal screening tests. More...
18 Oct 2022
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