Molecular Diagnostics
Rectal Colonization by Klebsiella Leads to Different Risks for Bacteremia
Carbapenem-resistant Enterobacterales (CRE) represent a threat for public health, being among the top multidrug-resistant pathogens. Intestinal colonization by CRE is a risk factor for developing subsequent infection. More...20 Jul 2021
Telomerase Reverse Transcriptase Protein Expression Evaluated for Melanomas
Telomeres are regions of repetitive nucleotide sequences located at the ends of chromosomes that play a key role in the maintenance of genomic integrity and stability in cells. In normal nonneoplastic somatic cells, telomeres progressively shorten with successive cell divisions. More...19 Jul 2021
Metabolomic Analytical Approach Identifies Multiple Neonatal Errors of Metabolism Disorders
A recent paper demonstrated that an untargeted metabolomics analytical approach could identify many more neonatal disorders caused by inborn errors of metabolism (IEM) than could be found by traditional methods. More...19 Jul 2021
Rotavirus Co-Infection with Diarrheagenic Pathogens Detected by Different Methods
Diarrhea is the second most common cause of childhood mortality worldwide, with Group A Rotavirus (RVA) recognized as a leading diarrheagenic agent, causing 38% of acute diarrhea among children aged five and below worldwide. More...14 Jul 2021
Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection
The detection of specific DNA sequences is central to precision medicine, from pathogen identification to the risk assessment of human genetic diseases to disease prognosis. While technologies exist for DNA detection, they tend to be limited either in terms of multiplexing, turnaround times, quantification accuracy, or specificity for single-nucleotide differences. More...13 Jul 2021
In Other News
Genotyping Helps Avoid Needless Bone Marrow Biopsies in African-Americans
A Novel Nanowell Array Sensor for POC Measurement of Stress Hormones
Novel Stool Biomarker Screening Tests Detect Colorectal Cancer and Inflammatory Bowel Disease
Protein Biomarker Blood Test Accurately Detects Alzheimer’s Disease
Sensitive PCR Test Predicts Treatment Response in Metastatic Head and Neck Cancers
Blood-based Liquid Biopsy Test Accurately Detects More Than Fifty Types of Cancer
Circulating Tumor DNA Following Surgery Predicts Bladder Cancer Recurrence
A Nanowire-based Liquid Biopsy Method for Detection of Tumors of the Central Nervous System
The OncoMasTR Test Accurately Identifies Risk of Breast Cancer Recurrence
Highly Sensitive Molecular Test Detects Cases of Tuberculosis
Serum Thrombospondin 2 Identified as Biomarker for Patients at Risk of Nonalcoholic Fatty Liver Disease
Genetic Variants Associated with Unexplained Sudden Cardiac Death
CtDNA Analysis Assesses Early Relapse Detection in Colorectal Cancer
Liquid Biopsies Detect Pediatric Bone Tumors Based on Epigenetic Profiles
Genomic Differences Cause Racial Disparities in Prostate Cancer
Plasma Levels of Neurofilament Light Chain Protein Accurately Identify Neurodegenerative Disease Patients
A Mucin Protein Is a New Prognostic Biomarker for Chronic Obstructive Pulmonary Disease
Low-Cost Transcriptional Diagnostic Accurately Categorizes Lymphomas
Circulating Tumor DNA Following Surgery Predicts Colorectal Cancer Recurrence
Familial Hypercholesterolemia Tends to Slip Past Genetic Tests
Personalized CtDNA Analysis Detects Minimal Residual Disease
Blood MicroRNA Biomarker Distinguishes Myocarditis from Myocardial Infarction
A Novel Liquid Biopsy Technique for Diagnosis of Cancers in Children
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.