Molecular Diagnostics
Amniotic Fluid Cells RNA-Sequencing Demonstrates Diagnostic Potential in Deciphering Rare Diseases
Researchers have discovered that applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis of rare diseases could help more families with tailored clinical management. It is the first proof-of-concept study to demonstrate the potential clinical utility of amniotic fluid cells RNA-sequencing. More...05 Jan 2023
CRISPR Protein Could Yield New Tests for Many Viruses
In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA. With its abilities to target so many types of genetic material, the discovery holds potential for the development of new inexpensive and highly sensitive at-home diagnostic tests for a wide range of infectious diseases. More...05 Jan 2023
Nanopore Sequencing Detect Pathogens in Knee Periprosthetic Joint Infection
The number of total knee arthroplasty (TKA) is currently increasing substantially, and it is expected to increase more than two times in the next decade worldwide. With the increasing number of TKA, the number of prosthetic joint infections (PJIs) is also increasing, and PJI is currently regarded as the most common etiology for revision TKA. More...05 Jan 2023
Multi-Cancer Detection Blood Test to Enable Early Diagnosis and Treatment
The US Food and Drug Administration (FDA) has granted Breakthrough Device Designation to a Multi-Cancer Detection Blood Test (MCDBT) that is intended for early detection of multiple cancer types (esophageal, liver, lung, ovarian, and pancreatic cancers) in adults of either sex, aged 50-75 years old, at average risk for cancer. More...04 Jan 2023
Blood-Based Screening Test for Colorectal Cancer Demonstrates Strong Clinical Performance
A blood test for the detection of colorectal cancer (CRC) has demonstrated 83% sensitivity with specificity of 90%, paving the way for the first potential US FDA-approved blood test for CRC screening. More...03 Jan 2023
Blood Test Helps Diagnose Inaccessible Brain Tumors
Presently, no blood test is available for diagnosing brain cancers, and doctors have to rely on complex surgical procedures to obtain tumor tissue for histopathological evaluation. Now, a new blood test can detect the cells released from the brain tumor that are extremely rare and hard to detect, enabling early diagnosis and treatment. More...03 Jan 2023
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
