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Molecular Diagnostics

Image: RNAs are labeled red in a mouse brain (Photo courtesy of Harvard Medical School and the Wyss Institute).

Fluorescent In Situ Sequencing Helps Diagnose Sick Tissues Early

Fluorescent in situ sequencing has potential applications, such as new diagnostics that spot the earliest signs of disease.   More...
26 Mar 2014
Image: Spongiform change in vCJD (Photo courtesy of Wikimedia Commons).

Highly Specific Blood Test Detects Creutzfeldt-Jakob Disease

A preliminary study has indicated that a blood test for infection by the prion that causes vCJD has sufficient sensitivity and specificity to justify a large study comparing vCJD prevalence in the United Kingdom with a bovine spongiform encephalopathy-unexposed population.  More...
20 Mar 2014
Image: The M220 Focused-ultrasonicator (Photo courtesy of Covaris).

Preleukemic Hematopoietic Stem Cells Identified in Acute Leukemia

A preleukemic stem cell has been discovered that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia.   More...
12 Mar 2014

Combined Screening Suggested to Better Detect ALK Rearrangements in Samples from Non-Small-Cell Lung Cancer Patients

Anaplastic lymphoma kinase rearrangements occur in 1% to 7% of non-small-cell lung cancers, but nearly 25% of samples from NSCLC patients with ALK rearrangements were not identified when analyzed by either fluorescent in situ hybridization or immunohistochemistry.  More...
12 Mar 2014

High Diagnostic Accuracy Demonstrated for New Kidney Cancer Test

A clinical study finds a new genomic test for kidney cancer highly valuable for diagnosis, subtyping, and outcome prediction for renal cancers, an important complement to tissue staining based pathology.   More...
10 Mar 2014
Image: The Bioanalyzer RNA 6000 Nano LabChip Kit (Photo courtesy of Agilent Technologies).

Genetic Markers Found for Breast Cancer Brain Metastasis

The development of brain metastases from breast cancer depends on several prognostic factors, including younger age, ethnicity, and hormone receptor negative status.  More...
06 Mar 2014

Genomic Assay Predicts Probability of Heart Transplant Rejection

Results obtained over time by a gene expression assay used to monitor heart transplant patients for signs of rejection may be able to predict the likelihood of rejection in the future.  More...
05 Mar 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.