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Molecular Diagnostics

Image: Biacore Sensor Chip for ligand capture (Photo courtesy of GE Healthcare).

Newly Identified Immune Receptor Activates B Cells in Autoimmunity

A newly identified immune protein influences each person's response to vaccines and risk for autoimmune diseases like systemic lupus erythematosus and multiple sclerosis.   More...
01 Jan 2014
Image: An 8-month-old infant with an extensive cleft palate associated with the genetic condition Bamforth- Lazarus syndrome (Photo courtesy of Maynika V Rastogi and Stephen H LaFranchi).

Dominant Gene Mutations Causes Van der Woude Syndrome

A new gene has been identified that is related to the Van der Woude syndrome, the most common syndrome with cleft lip and palate.   More...
01 Jan 2014
Image: Map illustrating relative rates of type 2 diabetes in countries in the Americas. The newly discovered genetic risk factor for type 2 diabetes could account for as much as 20% of the increased prevalence in these populations (Photo courtesy of Broad Institute; adapted by Lauren Solomon, Broad Communications, from image at International Diabetes Federation).

New Genetic Risk Factor for Type 2 Diabetes Uncovered

Another genetic factor has now been found to contribute to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.  More...
31 Dec 2013
Image: In vitro fertilization of the oocyte (Photo courtesy of Dr. Geoffrey Sher).

Genome Sequencing Detects Defects in Human Oocytes

A safe, accurate, and low-cost method to select genetically normal embryos for the in vitro fertilization procedure can increase a couple's chance of producing a healthy child.  More...
30 Dec 2013
Image: Orbitrap Velos Pro hybrid ion trap mass spectrometer (Photo courtesy of Thermo Scientific).

Standardized Assays Developed to Quantify Human Proteins

The feasibility of large-scale standardized protein measurements, which are necessary for validation of disease biomarkers, has been developed.    More...
30 Dec 2013
Image: Histopathology of pancreatic endocrine tumor (insulinoma) (Photo courtesy of Wikipedia Commons).

Gene Mutation Identified as Diagnostic Target for Insulinoma

A recurrent mutation in the transcription factor Yin Yang 1 is related with insulinoma oncogenesis, implicating a potential marker for the diagnosis and treatment of functional pancreatic neuroendocrine tumors.  More...
26 Dec 2013
Image: Normal brain (left) compared with one from a severe case of Alzheimer’s disease (right) (Photo courtesy of US National Institute on Aging).

Rare Gene Variants Doubles Alzheimer's Disease Risk

Variations in a gene have been identified that doubles a person's risk of developing Alzheimer's disease later in life.    More...
26 Dec 2013
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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