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Molecular Diagnostics

Image: Histopathology of non-alcoholic fatty liver disease showing the liver with prominent macrovesicular steatosis (Photo courtesy of Nephron).

Liver Values Elevated in Overweight Children with Gene Mutation

Genetic polymorphism has been strongly associated with liver fat content and plasma alanine aminotransferase levels in obese adults and children, but little is known about these relationships in normal weight individuals.  More...
07 Jul 2014
Image: Histology of squamous cell carcinoma of the bladder (Photo courtesy of British Columbia Cancer Agency).

Simple Urine Test Diagnoses Bladder Cancer Early

A highly-specialized urine test can detect bladder cancer as much as three to six months earlier than an invasive cystoscopy procedure and can help physicians diagnose the disease at an initial stage, when treatment might be more effective.   More...
03 Jul 2014
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MicroRNA Could Help Diagnose Mental Disorders

The link between dysregulated serotonergic activity and depression and anxiety disorders is well established, yet the molecular mechanisms underlying these psychopathologies are not fully understood.  More...
02 Jul 2014

Mutations in the Apolipoprotein C3 Gene Lower Triglyceride Levels and Reduce Heart Disease Risk

Mutations, which prevent the normal functioning of the APOC3 gene, lower blood triglyceride levels and reduce the risk of developing coronary artery disease.  More...
30 Jun 2014
Image: The Applied Biosystem Veriti Thermal Cycler (Photo courtesy of Life Technologies).

High-Risk Female Groups Screened for Fabry Disease

Although measurement of lysosomal α-galactosidase A in women is not accurate for the diagnosis of Fabry disease, determining the range of the enzyme activity presented by heterozygous females could become a valuable tool for minimizing the burden of screening by DNA sequencing all potential carriers.   More...
26 Jun 2014
Image: The 3730xl DNA Analyzer (Photo courtesy of Applied Biosystems).

Molecular Makeup Uncovered in New Form of Cancer

The molecular signature and genetic structure has been revealed of a new form of cancer that begins in the nose and is called biphenotypic sinonasal sarcoma.   More...
25 Jun 2014
Image: Histopathology micrograph of prostatic acinar adenocarcinoma, the most common form of prostate cancer (Photo courtesy of Nephron).

Prostate Cancer Biomarkers Identified in Seminal Fluid

Improved diagnosis and management of one of the most common cancers in men, prostate cancer, could result from discovery that seminal fluid contains biomarkers for the disease.  More...
18 Jun 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.