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Molecular Diagnostics

Image: Histopathology showing degranulation of eosinophils (pink) with adjacent nerves (brown) in the duodenum of a patient with functional bowel disorder (Photo courtesy of Dr. Marjorie Walker).

Genetic Clue to Irritable Bowel Syndrome Found

Irritable bowel syndrome may be caused by genetics, diet, past trauma, anxiety and all are thought to play a role, but now, for the first time, a defined genetic defect that causes a subset of IBS has been reported.   More...
03 Apr 2014
Image: A cystic adenocarcinoma in the pancreas head; cross-section of CT scan with i.v. contrast injection (Photo courtesy of Wikimedia).

Proteomic Profiling Enables Earlier Diagnosis of Pancreatic Cancer

A newly developed method has correctly identified pancreatic cancer potential with higher accuracy than cytology and cyst fluid carcinoembryonic antigen testing, and could be used to improve prevention and reduce unwarranted surgery.  More...
02 Apr 2014

FDA Clears First-of-Its-kind Postnatal Test for Developmental Disabilities

The US Food and Drug Administration has recently cleared a new postnatal blood test to help diagnose children’s genetic-based developmental disabilities more comprehensively by enabling a high-resolution genome-wide analysis of genetic aberrations.  More...
02 Apr 2014
Image: Illumina HiSeq 2500 ultra-high-throughput sequencing system (Photo courtesy of Konrad Förstner).

New Gene Linked to Key Heart Attack Risk Factor

A previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks has been found.   More...
26 Mar 2014
Image: RNAs are labeled red in a mouse brain (Photo courtesy of Harvard Medical School and the Wyss Institute).

Fluorescent In Situ Sequencing Helps Diagnose Sick Tissues Early

Fluorescent in situ sequencing has potential applications, such as new diagnostics that spot the earliest signs of disease.   More...
26 Mar 2014
Image: Spongiform change in vCJD (Photo courtesy of Wikimedia Commons).

Highly Specific Blood Test Detects Creutzfeldt-Jakob Disease

A preliminary study has indicated that a blood test for infection by the prion that causes vCJD has sufficient sensitivity and specificity to justify a large study comparing vCJD prevalence in the United Kingdom with a bovine spongiform encephalopathy-unexposed population.  More...
20 Mar 2014
Image: The M220 Focused-ultrasonicator (Photo courtesy of Covaris).

Preleukemic Hematopoietic Stem Cells Identified in Acute Leukemia

A preleukemic stem cell has been discovered that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia.   More...
12 Mar 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.