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Molecular Diagnostics

Image: Histopathological image of breast fibroadenoma from a core needle biopsy (Photo courtesy of Dr. Jeremy Thomas).

Critical Gene Altered in Numerous Fibroadenoma Patients

Advanced DNA sequencing technologies have been used to identify a critical gene that was repeatedly disrupted in nearly 60% of fibroadenoma cases.  More...
13 Aug 2014
Image: Researchers used gene chips like this one to identify new genes that may be involved with the development of Parkinson\'s disease (Photo courtesy of the [US] National Human Genome Research Institute).

Six Previously Unreported Genes Linked to Risk of Developing Parkinson's Disease

 Genomic researchers have identified more than two dozen genetic risk factors implicated in the development of Parkinson's disease including six genetic loci that had not been reported previously. More...
13 Aug 2014
Image: The photomicrograph shows the appearance of a low grade carcinoma of the prostate that can be difficult to recognize as malignancy, particularly in small needle biopsies (Photo courtesy of the University of Washington).

Accurate Epigenetic Test Eliminates Superfluous Biopsies for Prostate Cancer

Two independent trials have now validated the performance of an epigenetic test that could provide physicians with a better tool to help eliminate unnecessary repeat prostate biopsies.  More...
06 Aug 2014

Mutation That Induces High Blood Pressure in Women Linked to Increased Heart Attack Risk

A mutation in women in the G-protein coupled estrogen receptor 30 gene generates a receptor with reduced activity that induces high blood pressure, the single biggest risk factor for heart attack and stroke.  More...
05 Aug 2014
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Innovative Methodology Translates Noncoding DNA in Colorectal Cancer

Although the genetic origins of cancers have been studied for a long time, scientists were not able to measure the role of noncoding regions of the genome until now.  More...
05 Aug 2014
Image: Histopathology of a child’s kidney showing one glomerulus (arrow) with matrix expansion and uniform thickening of the basement membrane. The tubules show mild atrophy and the interstitium contains patchy moderate infiltrates. The appearance is consistent with membranous nephropathy (Photo courtesy of Dr. S. K. Pradhan).

Genetic Test Predicts Therapeutic Response in Pediatric Kidney Disease

Genetic mutations in the kidney’s filtration barrier are frequently linked with a lack of response to immunosuppressive treatments among children with sporadic nephrotic syndrome.  More...
05 Aug 2014
Image: Papillary thyroid cancer showing grey lobulated tumor with central scar (Photo courtesy of Dr. Shahidul Islam).

Molecular Test Effectively Guides Extent of Initial Thyroidectomy

The routine use of a molecular testing panel increases the likelihood of performing the correct initial surgery for patients with thyroid nodules and cancer.  More...
05 Aug 2014
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Microblot-Array Liver Profile Kit


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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