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Molecular Diagnostics

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Early Gene Changes Identified That Precede Blood Cancer

DNA samples have been used to uncover early, precancerous genetic changes in the blood that are linked to increased chances of developing blood cancers such as leukemia, lymphoma or myelodysplastic syndrome.   More...
15 Dec 2014
Image: Histopathology of triple negative breast cancer (Photo courtesy of Joe Segen).

Gene Uncovered Associated with Aggressive Breast Cancer

A biomarker has been identified that is strongly associated with triple negative breast cancer, a highly aggressive carcinoma that often has early relapse and metastasis following chemotherapy.   More...
14 Dec 2014
Image: Proposed mechanism of genetic material from tumor entering into circulation (Photo courtesy of University of Utah).

Tumor Markers in Blood Underpins Future Bowel Cancer Screening

The positivity from a two-gene DNA blood test increases with the depth of cancer invasion, tumor size, stage and presence of metastases in bowel cancer patients.   More...
09 Dec 2014
Image: Photomicrograph of endometriosis of the ovary (Photo courtesy of Nephron).

Noninvasive Test for Endometriosis Developed

Endometriosis is diagnosed and staged at surgery, resulting in an 11-year latency from symptom onset to diagnosis, underscoring the need for less invasive, less expensive approaches.   More...
07 Dec 2014
Image: NanoFlares-specially designed stem cells that have been developed to detect blood-borne cancers. When the cells come in contact with cancerous cells, they emit light (Photo courtesy of the International Institute for Nanotechnology at Northwestern University).

Nanoflares Detect Live Tumor Cells in Human Blood

Metastasis portends a poor prognosis for cancer patients and primary tumor cells disseminate through the bloodstream before the appearance of detectable metastatic lesions.  More...
07 Dec 2014
Image: The Genome Sequencer 454FLX system (Photo courtesy of Roche).

Real-Time Genome Sequencing Helps Control Hospital Outbreak

Whole-genome sequencing (WGS) of bacterial isolates provides a promising contemporary method for investigating the epidemiology of outbreaks, particularly when coupled to clinical locational and temporal data.   More...
01 Dec 2014
Image: The BN II protein analyzer system (Photo courtesy of Siemens).

Sickle Cell Trait Linked to Chronic Kidney Disease Risk

Sickle cell trait is defined as inheritance of a single copy of the sickle mutation that results from a single base pair substitution in the gene encoding the β-globin chain of hemoglobin.   More...
30 Nov 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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