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Molecular Diagnostics

Image: Histopathology of a child’s kidney showing one glomerulus (arrow) with matrix expansion and uniform thickening of the basement membrane. The tubules show mild atrophy and the interstitium contains patchy moderate infiltrates. The appearance is consistent with membranous nephropathy (Photo courtesy of Dr. S. K. Pradhan).

Genetic Test Predicts Therapeutic Response in Pediatric Kidney Disease

Genetic mutations in the kidney’s filtration barrier are frequently linked with a lack of response to immunosuppressive treatments among children with sporadic nephrotic syndrome.  More...
05 Aug 2014
Image: Papillary thyroid cancer showing grey lobulated tumor with central scar (Photo courtesy of Dr. Shahidul Islam).

Molecular Test Effectively Guides Extent of Initial Thyroidectomy

The routine use of a molecular testing panel increases the likelihood of performing the correct initial surgery for patients with thyroid nodules and cancer.  More...
05 Aug 2014
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New Data Further Suggest Possibility of Blood Test for Cancers

New results using an innovative DNA mutation enrichment technology suggest the possibility of a simple blood test for various cancers.   More...
05 Aug 2014
Image: Scanning Electron Micrograph of the pathogenic fungus Cryptococcus gattii (Photo courtesy of Edmond Byrnes and Joseph Heitman).

New Test Developed to Diagnose Virulent Lung Fungus

The emergence of distinct populations of Cryptococcus gattii in the temperate North American Pacific Northwest was surprising, as this species was previously thought to be confined to tropical and semitropical regions.   More...
04 Aug 2014
Image: Microscopic analysis system automatically acquires up to eight slides with immunohistochemically stained sections and performs quantitative analysis of staining intensities (Photo courtesy of TissueGnostics).

New Technology Developed to Diagnose Cancer Cells

Patient tumors can be analyzed for aberrant activations of core cancer pathways by monitoring based on biomarker expression which ensures efficient treatment in targeted therapy.  More...
04 Aug 2014

Gene Variations Can Predict Radiation-Induced Toxicity Risk

Key genetic variants may affect how cancer patients respond to radiation treatments, according to new research.  More...
04 Aug 2014
Image: The GeneRead DNAseq Targeted Panels V2 kit (Photo courtesy of Qiagen).

Genomic Biomarkers Assess Treatment Prognosis in Blood Cancers

The biomarker gene, splicing factor 3B subunit 1, is believed to play a critical role in the prognosis of patients with myelodysplastic syndromes, a group of hematological cancers in which bone marrow does not produce enough healthy blood cells.  More...
04 Aug 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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