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Molecular Diagnostics

Image: The M220 Focused-ultrasonicator (Photo courtesy of Covaris).

Preleukemic Hematopoietic Stem Cells Identified in Acute Leukemia

A preleukemic stem cell has been discovered that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia.   More...
12 Mar 2014

Combined Screening Suggested to Better Detect ALK Rearrangements in Samples from Non-Small-Cell Lung Cancer Patients

Anaplastic lymphoma kinase rearrangements occur in 1% to 7% of non-small-cell lung cancers, but nearly 25% of samples from NSCLC patients with ALK rearrangements were not identified when analyzed by either fluorescent in situ hybridization or immunohistochemistry.  More...
12 Mar 2014

High Diagnostic Accuracy Demonstrated for New Kidney Cancer Test

A clinical study finds a new genomic test for kidney cancer highly valuable for diagnosis, subtyping, and outcome prediction for renal cancers, an important complement to tissue staining based pathology.   More...
10 Mar 2014
Image: The Bioanalyzer RNA 6000 Nano LabChip Kit (Photo courtesy of Agilent Technologies).

Genetic Markers Found for Breast Cancer Brain Metastasis

The development of brain metastases from breast cancer depends on several prognostic factors, including younger age, ethnicity, and hormone receptor negative status.  More...
06 Mar 2014

Genomic Assay Predicts Probability of Heart Transplant Rejection

Results obtained over time by a gene expression assay used to monitor heart transplant patients for signs of rejection may be able to predict the likelihood of rejection in the future.  More...
05 Mar 2014
Image: The FLUOstar Optima plate reader (Photo courtesy of BMG Labtech).

Gene Discovery Illuminates Cause of Bone Marrow Failure

A novel genetic defect has been identified among patients with bone marrow failure, which could reveal its underlying cause.  More...
04 Mar 2014
Image: Artist's rendition of circulating tumor cells and circulating tumor DNA (Photo courtesy of http://vyturelis.com).

Circulating Tumor DNA a Sensitive and Specific Cancer Biomarker

Digital polymerase chain reaction can be used for early detection of circulating tumor DNA in many types of cancer even in the absence of any circulating tumor cells.  More...
03 Mar 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.