Molecular Diagnostics
Gene Test Matches Treatment to Patients with Cancer of Unknown Origin
Cancer of unknown origin is defined as a tumor from a patient presenting with metastatic carcinoma that did not unequivocally originate from a confirmed primary site on the basis of available diagnostic methods. More...02 Mar 2015
New PCR Assay Rapidly Diagnoses Myotonic Dystrophy Gene Targets
In a proof-of-principle study, scientists have developed a conventional-PCR diagnostic test that specifically identifies myotonic dystrophy type 1 gene targets from whole blood samples in 15 minutes, obviating the need for prior DNA purification or concentration. More...01 Mar 2015
Transplanted Blood Cell Biomarker Associated with Improved Survival
Among patients with severe aplastic anemia who received stem cell transplant from an unrelated donor, longer leukocyte telomere length, a structure at the end of a chromosome was associated with increased overall survival at five years. More...23 Feb 2015
Whole Genetic Code of IVF Embryos Scanned for Mutations
Currently, the methods available for preimplantation genetic diagnosis of in vitro fertilized embryos do not detect de novo single-nucleotide and short indel mutations, which have been shown to cause a large fraction of genetic diseases. More...23 Feb 2015
Simple Method Monitors β-Cell Death in Type 1 Diabetes Individuals
The β-cell killing that characterizes type 1 diabetes is thought to begin years before patients present clinically with metabolic decompensation; however, this primary pathologic process of the disease has not been measured. More...17 Feb 2015
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In Other News
Blood Test Developed for Aggressive Bone Cancer
Simple Blood Test Can Predict Dementia Risk
Potential Biomarkers for High-Risk Colon Cancer Discovered
Genes Linked to Drug Resistance in Testicular Cancer
Mutated Gene Biomarker Identified for Rare Adrenal Tumors
Proteins Likely to Trigger Psoriasis Identified
Dominant Gene Mutation Causes Incurable Eye Disorder
Neglected Malaria Subspecies Characterized by Novel Molecular Assay
New Gene Identified That Drives Triple-Negative Breast Cancer
Karyomapping Proposed as Alternative to Preimplantation Genetic Diagnosis for Evaluation of IVF Embryos
Data Reinforce HPV as First-Line Test in Cervical Cancer Screening
Multiplex Assays Detect HSV-1/2 And Varicella Zoster Virus
DNA Sequencing of Liquid Biopsy Specimens Increases Accuracy of Prostate Cancer Diagnosis
Newborn Screening Test Detects Severe Combined Immunodeficiency
Breast Cancer Test Optimizes Treatment Recommendations
Genome Analysis Study to Aid Diagnosis of Rare Developmental Disorders
Canadian Researchers Identify Mutations Linked to Rare Form of Liver Cancer
Cell Culture Technique Leads to Tailor-Made Cancer Treatments
Whole Genome Sequencing Demonstrates Potential for Diagnosis and Discovery in the Cancer Genetics Clinic
Gene Expression Correlates with Lymphocyte Infiltration in Breast Cancer
Mutations in Rare Asbestos-Caused Cancer Identified by Targeted Next-Generation Sequencing
Genetic Tests for Breast Cancer Detect More Mutations
Genome Analysis Shows Meiosis Gene Mutation Causes Primary Ovarian Insufficiency
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.