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Molecular Diagnostics

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Molecular Test Identifies Acute Transplant Rejection

The development of noninvasive molecular assays to improve disease diagnosis and patient monitoring is a critical need in renal transplantation, as acute rejection increases the risk for chronic graft injury and failure.  More...
25 Nov 2014
Image: Histopathology of ovarian serous papillary borderline tumor, intracystic, without surface cortical involvement (Photo courtesy of Brown University).

Prognostic Biomarker Candidates Identified for Ovarian Cancer

Two independent classes of novel candidate prognostic markers for ovarian cancer have been identified advancing efforts to develop targeted therapies for the disease.  More...
25 Nov 2014

Kidney Transplant Patients Identified at High Risk of Rejection

A quantitative real-time PCR-based assay can identify kidney transplant patients who are at high risk of acute rejection.  More...
18 Nov 2014
Histopathology of colonic adenocarcinoma; the glands are enlarged and filled with necrotic debris (Photo courtesy of the University of Utah).

Promising Blood Biomarkers Isolated for Colorectal Cancer

The search for blood-borne biomarkers that could be used to screen for colorectal cancer has uncovered two promising candidates that may one day lead to the development of a simple blood test.  More...
12 Nov 2014
Image: Micrograph of a muscle biopsy from a patient with amyotrophic lateral sclerosis demonstrating the typical \"grouped atrophy\" of muscle fibers that occurs with denervation (Photo courtesy of the University of Utah).

ALS Associated Gene Identified Using Innovative Strategy

An innovative exome sequencing strategy has been used to identify a gene that encodes for a specific protein and is associated with familial amyotrophic lateral sclerosis, a fatal neurological disorder also known as Lou Gehrig's Disease.   More...
11 Nov 2014
Image: The FilmArray System, a multiplex polymerase chain diagnostic platform (Photo courtesy of BioFire Diagnostics).

Enterovirus D68 Genome Sequenced

In recent months, the rare Enterovirus D68 has spread rapidly across North America and caused severe respiratory illness in young children, with some requiring hospitalization.  More...
11 Nov 2014

Blood Test for Early-Onset Alzheimer's Disease Relies on Exosomal MicroRNA Biomarkers

A team of Australian biomedical researchers has devised a blood test based on expression profiling of small non-coding RNA’s, microRNA, for the diagnosis of early-onset Alzheimer's disease.   More...
09 Nov 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.