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Molecular Diagnostics

Next Generation Sequencing Reveals Genetic Basis for Congenital Cataracts

Applying the latest high-throughput, next-generation DNA sequencing technology has enabled researchers in the United Kingdom to diagnose children with rare diseases that are characterized by the formation of congenital cataracts.  More...
01 Sep 2014

Biomarker for an Aggressive Breast Cancer Identified

Using bioinformatics, scientists have identified an overactive transcription factor strongly associated with basal-like breast carcinoma—providing a biomarker with potential for improved diagnostics and as a smart target for new therapeutics for patients with this highly aggressive, often chemotherapy-resistant cancer.  More...
31 Aug 2014
Image: The MassARRAY Analyzer 4 mass spectrometry system (Photo courtesy of Sequenom).

Biomarker Identified for Head and Neck Cancers

Evidence has been found suggesting that the deleterious health effects of a mutated gene may in large part be due to other genetic abnormalities, at least in head and neck squamous cell carcinoma.   More...
27 Aug 2014

Lyophilized Mastermixes and qPCR Kits Assist Pathogen Detection

A range of real-time polymerase chain reaction kits is offered for human pathogen detection, food testing, veterinary and agricultural testing, biothreat detection, and more.  More...
26 Aug 2014
Image: A technical breakthrough for DNA imaging has been achieved that should quicken diagnosis of diseases for which analysis of DNA from single-cells is critical, such as early stage cancers and various pre-natal conditions (Photo courtesy of McGill University and Génome Québec Innovation Center).

Breakthrough DNA Analysis Technology to Hasten Problem Diagnosis

Researchers have achieved a technical breakthrough that should result in speedier diagnosis of diseases for which analysis of DNA from single-cells is critical, such as early stage cancers and various prenatal conditions.   More...
25 Aug 2014
Image: The Q700 microsonicator (Photo courtesy of Qsonica).

Urinary Biomarker Discovered in Variant Creutzfeldt-Jakob Disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease has been detected in the urine of patients with the disease.  More...
20 Aug 2014
Image: Histopathology of non-comedo breast intraductal carcinoma showing distended duct with intact basement membrane, micropapillary, and early cribriform growth pattern (Photo courtesy of Dr. Rachel Swart, MD, PhD).

New Gene Tied to Major Breast Cancer Risk

Clinical testing for genes that confer a predisposition to breast cancer has been revolutionized by next-generation sequencing and multigene panels that allow relatively inexpensive and rapid genetic profiling are now in widespread use.   More...
20 Aug 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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