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Molecular Diagnostics

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New Gene Mutations Found for Wilms Tumor

The genetic causes of Wilms tumor, a type of kidney cancer found only in children, has been revealed by whole-exome sequencing identifying missense mutations in the microRNA-processing enzymes.  More...
18 Sep 2014
Image: Innogenetics sandwich enzyme-linked immunosorbent assays for Alzheimer disease biomarkers (Photo courtesy of Fujirebio).

APOE Genotype Biomarkers Evaluated for Alzheimer Disease

Cerebral spinal fluid levels of β-amyloid 42 are associated with the diagnosis of Alzheimer disease and accumulation in the brain independent of apolipoprotein E gene makeup.    More...
18 Sep 2014
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Image: A Boyden Chamber for cell transmigration (Photo courtesy of Neuro Probe).

Biomarker Identifies Breast Cancers with Poor Prognoses

Breast cancers are stratified into distinct subtypes, which influence therapeutic responsiveness and patient outcome, and those with luminal breast cancers are often associated with a better prognosis relative to other subtypes, but subsets of patients with luminal breast cancer remain at increased risk of cancer-related death.   More...
10 Sep 2014
Image: Histopathology of glioblastoma multiforme in the brain showing vascular endothelial proliferation (Photo courtesy of Dimitri P. Agamanolis, MD).

Blood Test May Revolutionize Brain Cancer Diagnosis

High-throughput sequencing studies of tumor genomes have produced new molecular markers that have enhanced classification of glioblastoma multiforme and highlighted molecular pathways that propagate pathogenesis and progression.  More...
09 Sep 2014
Image: Histopathology of a hepatoblastoma, a type of liver cancer found in infants and young children (Photo courtesy of Nephron).

Gene Identified That Promotes Childhood Cancers

A gene has been identified that contributes to the development of several childhood cancers and this could lead to new strategies for targeting certain childhood cancers at a molecular level.   More...
03 Sep 2014
Image: The characteristic Malar rash or butterfly rash seen in a patient with systemic lupus erythematosus (Photo courtesy of the National Institute of Arthritis and Musculoskeletal and Skin Diseases).

Genetic Key to Lupus Shows Potential of Personalized Medicine

DNA sequencing of a systemic lupus erythematosus patient has identified a specific genetic mutation that is causing the disease, opening the way for personalized treatments.  More...
02 Sep 2014

Next Generation Sequencing Reveals Genetic Basis for Congenital Cataracts

Applying the latest high-throughput, next-generation DNA sequencing technology has enabled researchers in the United Kingdom to diagnose children with rare diseases that are characterized by the formation of congenital cataracts.  More...
01 Sep 2014
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Antipsychotic TDM Assays
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WS-Si1500


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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