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Molecular Diagnostics

Image: Photomicrograph of the herpes simplex virus, within tissue taken from a penile lesion of a patient with genital herpes (Photo courtesy of the Centers of Disease Control and Prevention).

Globally Accurate Diagnostic Test Developed for Herpes

A universally accurate diagnostic test for human herpes simplex viruses may soon be developed and that may also lead to the development of a vaccine that protects against the virus.  More...
25 Aug 2015

Padlock Probe Assay Rapidly Detects Cardiac Disease Gene Mutations

A recent paper described a novel next generation sequencing assay for detecting cardiac disease gene mutations with improved accuracy, flexibility, turnaround time, and cost.   More...
25 Aug 2015
Image: The LTQ Orbitrap Elite mass spectrometer (Photo courtesy of Thermo Scientific).

Biomarker Identified in Breast and Prostate Cancers

A novel genetic biomarker has been identified responsible for the progression of many breast and prostate cancers and these finding could bolster efforts to better identify patients who respond to certain types of chemotherapy drugs that attack the most aggressive forms of cancer.  More...
25 Aug 2015
Image: Immunohistochemical staining of colorectal adenocarcinoma showing nuclear and cytoplasmic staining for β-catenin (Photo courtesy of Indiana University School of Medicine).

Biomarker Tied to Poor Survival for Colorectal Cancer Patients

Biomarkers for predicting prognosis are critical to treating colorectal cancer patients, and a subunit of a signalosome is overexpressed in CRC samples and that overexpression is correlated with poor patient survival.  More...
24 Aug 2015
Image: Eggs of Schistosoma mansoni in an unstained wet mount (Photo courtesy of the CDC – [US] Centers of Disease Control and Prevention).

Microscopy and Molecular Assay Compared for Schistosomiasis Diagnosis

The current reference test for the detection of Schistosoma mansoni in endemic areas is stool microscopy based on one or more Kato-Katz stool smears, but this technique is highly observer-dependent and has suboptimal sensitivity.  More...
12 Aug 2015
Image: A digital artist's impression of the human papillomavirus or HPV (Photo courtesy of Christian Anthony).

HPV16 in Oral Rinses Predicts Prognosis in Oropharyngeal Cancer

The presence of persistent human papillomavirus type 16 DNA in oral rinses after treatment for HPV-related oropharyngeal cancer is rare, but it appears to be associated with poor prognosis and therefore may have potential as a long-term tool for tumor surveillance.  More...
12 Aug 2015
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Blood Markers Identify Women at Risk for Postpartum Depression

The interaction between oxytocin receptor DNA methylation and genotype has been investigated and whether it is associated with risk of postpartum depression in women without depression in pregnancy.  More...
11 Aug 2015
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.