Molecular Diagnostics
Strange Chimeras Defy Scientific Understanding of Human Genetics
The human genome is far more complex than thought, with genes functioning in an unexpected fashion that scientists have wrongly assumed must indicate cancer as gene fusions and their encoded products fusion ribonucleic acids (RNAs) and proteins are viewed as one of the hallmarks of cancer. More...18 Oct 2016
New Genetic Links Identified for Heart Disease Risk Factors
Genetics have been implicated in cardiovascular and blood diseases for some time, however as these are complex diseases, it is extremely difficult to find specific genetic causes, but large scale genomic datasets can be used to help identify potential novel biological targets for studying cardiovascular and other diseases. More...14 Oct 2016
Field Test Allows Rapid Diagnosis of Chikungunya Virus Infection
Chikungunya virus (CHIKV) infection causes symptoms that are similar to Dengue and Zika as well as other viral diseases, including influenza and accurate diagnosis of CHIKV is important for effective outbreak responses, including patient management and mosquito control. More...12 Oct 2016
Quantitative Molecular Diagnostic Methods Identify Causes of Childhood Diarrhea
The number of cases of childhood diarrhea attributed to pathogens such as bacteria, parasites, viruses or other infections has been substantially underestimated and may be nearly twice as high as previous analysis suggests. More...06 Oct 2016
Genomic Fingerprinting Helps Predict Prostate Tumor Aggressiveness
Next-generation sequencing is revealing genomic heterogeneity in localized prostate cancer (CaP), but incomplete sampling of CaP multiclonality has limited the implications for molecular subtyping, stratification, and systemic treatment. More...06 Oct 2016
Extended Multilocus Sequence Typing Developed for Leptospirosis
Leptospirosis is a zoonotic disease caused by pathogenic species of Leptospira that can be carried naturally by most mammalian species and transmission to humans most commonly occurs via direct animal contact or via water contaminated with animal urine. More...05 Oct 2016
Genetic Cause Deciphered for Inherited Nerve Damage Afflicting Older Adults
An international team of researchers has identified a gene, MME, with a causative link to late-onset autosomal dominant axonal polyneuropathies. Patients initially develop loss of sensation and pain, then the illness can advance rapidly and lead to paralysis, inability to walk, and wheelchair dependency. More...05 Oct 2016
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In Other News
DNA Analysis Clarifies Ancestry of Triple-Negative Breast Cancer Patients
New Genes Implicated in High Blood Pressure Regulation
New Standardized Whole Genomes Released to Improve Quality Control
Test Developed for Healthcare-Acquired Infections Validated
Tumor Analysis Method Identifies High-Risk Prostate Cancer
Rare Inflammatory Disease Identified in Children
Proteomic Testing May Enable NIV Diagnosis of Respiratory Pathologies in Preterm Newborns
Combined Use of Assays Identifies Cancer Patient Response to Crizotinib
Blood Test Detects New Breast Cancer Subtype
Rapid Molecular Diagnostic Test Detects Zika Virus
Genetic Polymorphism Associated with Increased Cardiovascular Mortality
New Method Simplifies Blood Biomarker Discovery and Analysis
Fatal Fungal Infection Has Unique Growth Patterns
New Types of African Salmonella Associated with Lethal Infection
First Epigenetic Signature Test to Classify Metastasis Tumors of Unknown Origin
Inherited Genetic Variant Increases Risk of Chronic Lymphocytic Leukemia
Immune Analysis of Biopsies Predicts Response to Melanoma Immunotherapy
Genetic Analysis of Lesions Provides Accurate Esophageal Cancer Test
Molecular Testing Accuracy for Clostridium difficile Scrutinized
Study Leads to Improved Diagnosis of Inherited Heart Muscle Disease
Early Detection Identified for Leukemia Patients' Resistance to Therapy
Cell-Free DNA Sequencing Confirms Myelodysplastic Syndrome Diagnosis
Simple Sensitive Assays Used for Analyzing Fragile X Syndrome
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.