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Molecular Diagnostics

Image: Schematic drawing showing the differences between a normal lung and a cystic fibrosis lung (Photo courtesy of NCHPEG).

Fast and Accurate Cystic Fibrosis Test Developed for Newborns

A fast, inexpensive and highly accurate test to screen newborns for cystic fibrosis has been developed, which detects virtually all mutations in the cystic fibrosis gene.  More...
14 Feb 2016
Image: Colonies of typical Listeria monocytogenes as they appear when grown on Listeria-selective agar (Photo courtesy of Dr. James Folsom).

Listeria Hypervirulence Uncovered by Harnessing Its Biodiversity

The Listeria monocytogenes bacterium responsible for the severe foodborne infection, listeriosis, especially in pregnant women and the elderly is subjected to a stringent microbiological monitoring system.  More...
14 Feb 2016
Image: Patients whose stage II colon cancer tested negative for CDX2 expression (left) had a worse prognosis than those whose cancer tested positive (right) (Photo courtesy of Columbia University Medical Center).

Prognostic Biomarker Found for Colon Cancer Patients

The majority of colon cancer patients whose tumors have started to travel to nearby tissue but no further are cured by surgery alone, but in a minority of these stage II colon cancer cases the cancer returns and the patients die.  More...
10 Feb 2016
Image: Peripheral blood smear of a patient with acute myeloid leukemia (Photo courtesy of Dr. Abbas H. Abdulsalam).

Blood Test Improves Treatment for Acute Myeloid Leukemia

A simple blood test has been developed that is capable of detecting trace levels of leukemia cells remaining after intensive chemotherapy. The test can predict which patients with acute myeloid leukemia are at risk of their cancer returning in the future, helping to guide doctors on what further treatment is needed.   More...
10 Feb 2016
Image: MILLIPLEX MAP Human Metabolic Hormone Magnetic Bead Panel (Photo courtesy of EMD Millipore).

Aberrant Gene Expression Predicts Metastatic Endometrial and Lung Cancers

The spread of cancer cells from the initial site of occurrence, the primary site, to other secondary tissues is called metastasis, and contributes to poor or limited response of cancer cells to treatments, which results in death.  More...
10 Feb 2016
Image: Sporangiophores, columellae and primitive rhizoids of Rhizomucor spp., the zygomycetous fungus detected by the PathoChip, which has the ability to detect all known viruses, as well as a variety of bacteria, fungi, helminths, and protozoa (Photo courtesy of the University of Adelaide).

Fungal Infection Identified by Pathogen Detection Array Technology

Patients who are undergoing treatment for diseases such as cancer often face the added challenge of a compromised immune system, which can be challenging to both of their condition and the drugs used to treat it, leaving them vulnerable to various opportunistic infections.  More...
09 Feb 2016
Image: Histopathology of a brain tumor called oligodendroglioma diagnosed by the highly cellular lesion composed of cells resembling fried eggs with distinct cell borders moderate-to-marked nuclear atypia (Photo courtesy of Nephron).

Rapid Test Accurately Profiles Brain Tumor Genetics

Brain tumors can be rapidly and accurately profiled with a next-generation, gene-sequencing test recently developed. The test, called GlioSeq, is now being used by oncologists to help guide treatment planning of brain cancers.  More...
09 Feb 2016
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Automated MALDI-TOF MS System
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