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Molecular Diagnostics

Prostate Cancer Specific RNAs Identified in Urine and Tissue

Researchers have discovered a set of potential-biomarker RNAs that may pave the way to a more reliable prostate cancer screening assay.  More...
27 Oct 2014
Image: In contrast to tests that use MPSS (massively parallel shotgun sequencing), randomly sequencing all cell-free DNA (cfDNA), the Harmony test focuses on cfDNA from the chromosomes of interest. This unique, directed approach allows deeper analysis and ultimately yields more accurate results (Photo courtesy of Ariosa Diagnostics).

DNA-Based Blood Test Detects Down Syndrome as Early as the Tenth Week of Pregnancy

Down syndrome can now be detected using a noninvasive blood test to evaluate cell-free DNA found in maternal blood as early as 10 weeks into pregnancy.   More...
27 Oct 2014
DIASOURCE (A Biovendor Company)
Image: Tumor cell populations identified using digital image analysis from a stained pathology slide, with the tumor regions detected and now colored orange (Photo courtesy of Definiens).

Biomarker Reveals Cause of Papillary Thyroid Carcinoma

The expression of the CAP-GLY domain containing linker protein 2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin.  More...
26 Oct 2014
Image: The DEPArray System for analyzing individual cells (Photo courtesy of Silicon Biosystems).

Genetic Mutation Detected in Circulating Tumor Cells

Tissue biopsies from metastatic cancer patients are invasive procedures that are frequently impossible due to the lack of accessible lesions, but a sample is required for genetic analysis.   More...
26 Oct 2014
Image: The Ion Torrent Ion AmpliSeq Cancer Primer Pool kit (Photo courtesy of Life Technologies).

Molecular Immunohistochemical Profiling Identifies Invasive Breast Carcinoma

Molecular and immunohistochemical profiling of invasive micropapillary carcinoma of the breast was used to identify potentially useful markers for targeted therapies with a focus on a specific gene mutation.   More...
23 Oct 2014
Image

Biomarkers Identified for Early Detection of Colon Cancer

Colorectal cancer is still one of the most frequent and deadly cancers world-wide in both women and men and the prevention of this disease is, therefore, a significant public health issue.  More...
22 Oct 2014
Image: The G-Storm GS4 Thermal Cycler (Photo courtesy of Labtech International Ltd.).

Type 2 Diabetes Caused by Low Vitamin D Disputed

Low circulating concentrations of 25-hydroxyvitamin D, a marker of vitamin D status, are associated with an increased risk of type 2 diabetes, but whether this association is causal remains equivocal.  More...
16 Oct 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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