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Molecular Diagnostics

Image: Histopathology of metastatic carcinoma in liver tissue from a patient with colorectal cancer (Photo courtesy of Nikon).

Tumor Biopsies with Blood Monitoring Show Lesion-Specific Response

Metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug and the usual practice is to biopsy a single metastatic lesion to test for new mutations that can guide the selection of next-line therapies.   More...
24 Feb 2016
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Molecular Type 2 Diabetes Biomarker Identified

Type 2 diabetes mellitus is an established risk factor for a wide range of vascular diseases, including ischemic stroke as well as heart attacks, neuropathy and blindness.    More...
23 Feb 2016
Image: The Gel Doc XR+ System enables quick and easy visualization, documentation, and analysis of nucleic acid and protein gels, blots, and macroarrays (Photo courtesy of Bio-Rad Laboratories).

Nanotechnology Helps Detects Biomarkers of Cancer

The detection and quantification of short nucleic acid sequences has many potential applications in studying biological processes, monitoring disease initiation and progression, and evaluating environmental systems.  More...
22 Feb 2016
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Gene Mutation Provides Clue to Vibratory Urticaria

Patients with autosomal dominant vibratory urticaria have localized hives and systemic manifestations in response to dermal vibration, with coincident degranulation of mast cells and increased histamine levels in serum.   More...
15 Feb 2016
Image: Schematic drawing showing the differences between a normal lung and a cystic fibrosis lung (Photo courtesy of NCHPEG).

Fast and Accurate Cystic Fibrosis Test Developed for Newborns

A fast, inexpensive and highly accurate test to screen newborns for cystic fibrosis has been developed, which detects virtually all mutations in the cystic fibrosis gene.  More...
14 Feb 2016
Image: Colonies of typical Listeria monocytogenes as they appear when grown on Listeria-selective agar (Photo courtesy of Dr. James Folsom).

Listeria Hypervirulence Uncovered by Harnessing Its Biodiversity

The Listeria monocytogenes bacterium responsible for the severe foodborne infection, listeriosis, especially in pregnant women and the elderly is subjected to a stringent microbiological monitoring system.  More...
14 Feb 2016
Image: Patients whose stage II colon cancer tested negative for CDX2 expression (left) had a worse prognosis than those whose cancer tested positive (right) (Photo courtesy of Columbia University Medical Center).

Prognostic Biomarker Found for Colon Cancer Patients

The majority of colon cancer patients whose tumors have started to travel to nearby tissue but no further are cured by surgery alone, but in a minority of these stage II colon cancer cases the cancer returns and the patients die.  More...
10 Feb 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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