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Molecular Diagnostics

Image: The Odyssey CLx scanner for Western Blot analysis (Photo courtesy of LiCor).

Parkinson's Disease Biomarker Found in Urinary Samples

A biomarker helps physicians predict, diagnose or monitor disease, because the biomarker corresponds to the presence or risk of disease, and its levels may change as the disease progresses. More...
20 Jul 2016
Image: The breakthrough 7-gene blood test may enable physicians to determine whether their patients have a bacterial or viral infection (Photo courtesy of Erin Kunkel and Stanford University Medical Center).

Low-Cost Genetic Test Can Distinguish Bacterial from Viral Infections

Upon identifying a set of seven relevant genes, a breakthrough rapid blood test has been developed that, with further development and testing, may soon enable physicians to determine if a patient has a bacterial or viral infection. More...
19 Jul 2016
Image: Mitochondria. Researchers have inherited mutations in the TMEM126B gene that cause debilitating and often fatal disease from infancy, and have developed a rapid diagnostic test that has already identified 6 patients from 4 families (Image courtesy of Newcastle University).

Rapid Genetic Test Developed for an Often Fatal Mitochondrial Disease

Researchers have discovered disease-causing inherited mutations in the TMEM126B gene and developed a test providing rapid diagnosis of related mitochondrial disorders. Defects in TMEM126B cause problems with energy generation in muscles, and can lead to muscular weakness, blindness, fatal heart failure, liver failure, learning disability, diabetes, and seizures. There is currently no cure and affected children often die in early infancy. More...
19 Jul 2016
Image: An invasive adenocarcinoma (the most common type of colorectal cancer). The cancerous cells are seen in the center and at the bottom right of the image (blue). Near normal colon-lining cells are seen at the top right of the image (Photo courtesy of Wikimedia Commons).

Detection of Circulating Tumor DNA Predicts Colon Cancer Recurrence

A team of American and Australian cancer researchers has demonstrated that circulating fragments of tumor DNA (ctDNA) could serve as a biomarker for identifying patients with high risk of recurrence of colon cancer. More...
18 Jul 2016
Image: The E220 focused-ultrasonicator for DNA fragmentation (Photo courtesy of Covaris).

Genetic Causes of Bowel Cancer Clarified

Colorectal cancer (CRC) displays a complex pattern of inheritance and it is postulated that much of the missing heritability of CRC is enshrined in high-impact rare alleles, which are mechanistically and clinically important. More...
14 Jul 2016
Image: The Thermo-Finnigan LTQ mass spectrometer (Photo courtesy of Thermo Fisher Scientific).

Plasma Mannose Levels May Indicate Diabetes Risk

Obesity is associated with an increased risk for a wide range of morbidities, including insulin resistance (IR), type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease (CVD). More...
14 Jul 2016
Image: A histology of the small intestinal mucosa; the normal is on the left. The mucosa involved by celiac disease (sprue) at the right has blunting and flattening of villi (Photo courtesy of the CDC).

Celiac Disease Triggered by Intestinal Viruses

Digestive problems, severe inflammation of the small intestine and nutritional deficiencies leading to anemia and osteoporosis force patients of the autoimmune condition celiac disease to follow a strict gluten-free diet for life. More...
14 Jul 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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