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Molecular Diagnostics

Image: A colorized scanning electron micrograph (SEM) of human prostate cancer cells (Photo courtesy of Dr. Gopal Murti).

Tumor Analysis Method Identifies High-Risk Prostate Cancer

A new way to identify which prostate cancer patients are likely to develop aggressive types of the disease, even if their tumors at first appear to be lower risk, has been created. More...
21 Sep 2016
Image: The nCounter analysis system (Photo courtesy of NanoString Technologies).

Rare Inflammatory Disease Identified in Children

A rare, deadly inflammatory disease among young children, known as otulipenia has been discovered, and it is caused by the malfunction of OTULIN, a gene on chromosome 5 that regulates the development of new blood vessels and the mobilization of infection-fighting cells and proteins. More...
20 Sep 2016
Image: Prof. Evgeny Nikovaev and senior fellow Alexey Kononikhin in front of the ultra high resolution MS instrument (Photo courtesy of the MIPT).

Proteomic Testing May Enable NIV Diagnosis of Respiratory Pathologies in Preterm Newborns

A team of researchers is developing its new method for noninvasive diagnosis and therapeutic response monitoring of conditions in preterm newborns based on marker sets now identified by proteome analysis of urine samples. More...
19 Sep 2016
Image: A positive case of lung tissue detected by IHC-staining for anaplastic lymphoma kinase (ALK) with Ventana ALK (D5F3) CDx assay (Photo courtesy of Ventana).

Combined Use of Assays Identifies Cancer Patient Response to Crizotinib

In screening of a large cohort for anaplastic lymphoma kinase (ALK) fusions through both fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) assays, researchers found many non-small cell lung cancer (NSCLC) patients who had negative and atypical FISH patterns accompanied with positive IHC results, who showed response to crizotinib treatment. More...
19 Sep 2016
Image: The QX200 Droplet Digital Polymerase Chain reaction  (ddPCR) system (Photo courtesy of Bio-Rad).

Blood Test Detects New Breast Cancer Subtype

A blood test has been developed that detects when the most common form of breast cancer has become resistant to treatment could double the average time it takes for the disease to progress, from around two and a half to around six months. More...
14 Sep 2016
Image: The GenRead isothermal nucleic acid amplification device (Photo courtesy of Orion Diagnostica).

Rapid Molecular Diagnostic Test Detects Zika Virus

Zika virus has only recently gained attention due to recent large outbreaks worldwide and an easy to use nucleic acid amplification test (NAAT) could play an important role in the early detection of the infection and patient management. More...
14 Sep 2016
Image: The LightCycler 480 II, a rapid high-throughput, plate-based real-time PCR amplification and detection instrument (Photo courtesy of Roche Diagnostics).

Genetic Polymorphism Associated with Increased Cardiovascular Mortality

The platelet-derived growth factor (PDGF) family performs a multitude of functions such as vasodilation, regulation of erythropoiesis, and wound repair, but are also major mitogens for fibroblasts and smooth muscle cells, and are involved in the atherosclerotic process in the body. More...
13 Sep 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.