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Clinical Chemistry

Image: The Vantera Clinical Analyzer offers the technology that has the ability to directly enumerate low-density lipoprotein (LDL) particle numbers (Photo courtesy of LipoScience).

LDL Particle Number Measured Using NMR Clinical Analyzer

Fully-automated high-throughput nuclear magnetic resonance spectroscopy has been developed to enable measurements in a clinical laboratory setting.   More...
25 Aug 2014
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Semiquantitative Urine Dipstick Evaluated for Microalbuminuria Screening

The urine microalbumin test is used as a screening test for the diagnosis of renal complications in diseases, such as diabetic nephropathy, cardiovascular disease, and hypertension.  More...
21 Aug 2014
Image: The Q700 microsonicator (Photo courtesy of Qsonica).

Urinary Biomarker Discovered in Variant Creutzfeldt-Jakob Disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease has been detected in the urine of patients with the disease.  More...
20 Aug 2014
Image: The NanoDrop 2000 Spectrophotometer (Photo courtesy of Thermo Scientific).

Small RNAs in Blood May Reveal Heart Injury

An increase in certain micro ribonucleic acids circulating in the blood are linked with injury to cardiac muscle and these molecules might provide the basis for a more sensitive diagnostic tool than those currently available.  More...
14 Aug 2014

Red Blood Cell Folate Level Is a Biomarker for Risk of Neural Tube Defects

The importance of maintaining high red blood cell levels of folate during pregnancy to reduce risk of neural tube defects was confirmed in a review of results obtained by a large study of expectant mothers in China.  More...
13 Aug 2014
Image: The new Triple Quad 4500MD, along with the new QTRAP 4500MD, LC/MS/MS systems now provide analytic clinical diagnostics with flexibility, exceptional sensitivity, and faster data acquisition (Photo courtesy of AB SCIEX).

New Mass Spectrometry Series Enhances Analytical Diagnostics

A leading mass spectrometry portfolio for analytic clinical testing has been expanded with a new series offering flexibility, exceptional sensitivity, and faster data acquisition. More...
12 Aug 2014
Image: Histology of amyotrophic lateral sclerosis showing markedly degenerated anterior spinal nerve root (cross section) with extensive demyelination (Photo courtesy of Dr. Hidehiro Takei, MD).

Blood Biomarkers Assessed In Amyotrophic Lateral Sclerosis Prognosis

Various biological markers have been proposed as potentially related to a better amyotrophic lateral sclerosis outcome including dyslipidemia, elevated levels of uric acid, and creatinine, and reduced granulocyte count.  More...
06 Aug 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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