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Clinical Chemistry

Image: Simple, low-cost paper-strip assay – novel urine test reveals the presence of proteinases associated with cancer (Photo courtesy of Bryce Vickmark and MIT).

Nano-Based Urine Test to Enable Low-Cost Point-of-Care Cancer Diagnosis

A simple, noninvasive paper strip-urine test using nanoparticle technology could help transform worldwide screening for cancer and other diseases.  More...
05 Mar 2014

Cortisol Identified as Biomarker for Severe Depression in Teenage Boys

A team of British neuroscientists has found a dynamic link between high levels of the hormone cortisol and chronic depression, especially among teenage boys.  More...
04 Mar 2014
Image: The Luminex100/200 System designed for multiplexing (Photo courtesy of Luminex).

Prognostic Tool Predicts Pediatric Septic Shock Mortality Risk

A tool has been developed that allows physicians to quickly and accurately predict the risk of death in children with septic shock, a systemic infection that damages vital organs.   More...
25 Feb 2014
Image: Immunohistochemistry showing positive CINtec p16 staining (Photo courtesy of Ventana).

Protein Test Improves Survival Prediction for Oropharyngeal Carcinoma

A simple protein test could prove more useful in predicting survival chances for patients with head-and-neck cancer compared to existing methods.  More...
13 Feb 2014
Image: The PAXgene Blood DNA Tube (Photo courtesy of PreAnalytiX GmbH).

Dedicated Blood DNA Collection Tube Receives European Marketing Approval

A new collection tube for routine clinical use that was designed to preserve DNA in blood samples was recently certified for use as a diagnostic product in Europe.  More...
13 Feb 2014
Image: The ADVIA 2120i Hematology System with Autoslide (Photo courtesy of Siemens).

Reference Ranges Established for Automated Cerebrospinal Fluid Cell Count

Cerebrospinal fluid cell count is an important analysis in the investigation of central nervous system infections, and new reference ranges for leukocytes in the CSF have been established.   More...
11 Feb 2014
Image: A “biosignature” of compounds in a breath test may reveal lung cancer (Photo courtesy of Elhuyar Fundazioa).

Exhaled Breath Compounds Identify Early Lung Cancer

The diagnosis of lung cancer can involve a number of tests, but specific compounds in exhaled breath have been discovered that may be used to diagnose the disease in its early stages.   More...
10 Feb 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.