Clinical Chemistry

Complete Blood Count Parameters Associated With Pancreatic Beta-Cell Function
The pathophysiology of type 2 diabetes mellitus (T2DM) involves insulin resistance (IR) and progressive deterioration of beta-cell function (BCF). Estimation of IR and BCF is essential for screening subjects at a high risk of T2DM and making treatment plans in clinical practice. More...19 May 2022

Lipid Measurements Show Potential as Alzheimer’s Disease Biomarkers
Brain changes accompanying ageing are varied and can include pathologies that lead to cognitive impairment, the commonest of which is Alzheimer’s disease (AD). Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. More...17 May 2022

Mindray Launches High Throughput BS-600M Chemistry Analyzer with Industry-Leading Small Footprint
Mindray (Shenzhen, China) has launched the new BS-600M, a powerful yet efficient chemistry analyzer designed to empower medium-volume laboratories with increased productivity, efficiency and reliability. More...16 May 2022

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury
Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...12 May 2022

Tear-Based Method Detects Breast Cancer
With advances in screening techniques, and adjustment of recommended screening guidelines, mortality rates due to breast cancer continue to decline. Despite the estimated waning in mortality rates, breast cancer still remains the highest cancer diagnosis of women globally. More...11 May 2022

Proteins Linked to COVID-19-Associated Inflammatory Syndromes
COVID-19 associated acute respiratory distress syndrome (COVID-19 ARDS) is one of the major manifestations of the severe cases, characterized by hypoxemic respiratory failure with bilateral lung infiltrate, as well as multi-organ dysfunction and extensive microthrombus formation. More...10 May 2022

Biochemical Abnormalities Among Celiac Disease Patients Referred for Antibody Testing
Celiac disease (CD) is a chronic disease occurring in all age groups and affecting approximately 1% of the population, although many cases of CD remain undiagnosed. This condition is caused by an abnormal immune response in genetically susceptible individuals triggered by the ingestion of gluten proteins from wheat, rye and barley. More...09 May 2022
In Other News
Smart Diaper Could Provide Quick and Painless Bedside Urinalysis
NT-proBNP Underestimates Heart Failure Risk for Certain Patients
Groundbreaking Study Points to Crucial Gap in Children’s Clinical Testing
Paper-Based Sensor Strip Rapidly Detects Sodium in Urine and Blood at POC
Elevated Lipoprotein(a) Mediates Risk of Atrial Fibrillation
Urine Testing Differentiates Glomerular from Tubulointerstitial Diseases on Kidney Biopsy
Lipidomics Approach Developed to Predict Cardiovascular Disease, Diabetes
Sex Hormones Influence HbA1c Levels in Non-Diabetic Population
Proteomic Blood Test Predicts Cardiovascular Risk
Urine Sediment Findings in Patients With COVID-19-Associated Renal Injuries
Diabetic Kidney Disease and Risk of Incident Stroke Among T2D Adults
Serum Antinuclear Antibody Correlated in Hispanic Pediatric Patients With NFLD
Pre-Analytical Stability of Serum Biomarkers for Neurological Disease Investigated
Midlife Lipid and Glucose Levels Are Associated With Alzheimer's Disease
Albumin-Related Ratios Investigated in HBV-Associated Decompensated Cirrhosis
Biomarkers Associated With Cardiovascular Outcomes in Psoriatic Patients
Serum Folate Deficiency in Older People Associated With Heightened Dementia
Serum Extracellular Vesicle Arginase 1 Measured In T2DM
Biosensors Use Non-Invasive Urinalysis and AI for Quick Assessment of Cancer Treatment
Proline-Specific Peptidase Activities in Plasma of Hospitalized COVID-19 Patients
High-Sensitivity Troponin I Explored Post-Cardiac Surgery
Repeatability and Reproducibility of a Handheld Quantitative G6PD Diagnostic
Essential Amino Acids Associated With Complications in Liver Transplant Recipients
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.