Clinical Chemistry


Simple Sarcopenia Screening Test Found to Predict Heart Failure Severity
Researchers have shown that the simple screening method originally developed to diagnose sarcopenia can be used, instead of CT or MRI, to quickly and easily predict severity of heart failure disease. They also found that the predictive capabilities of the brain natriuretic peptide (BNP) lab test for heart function can be further improved if coupled with a patient's sarcopenia test score. More...31 May 2016

Bioelectronic Device Detects Marker Linked to Neurodegenerative Diseases and Cancer
Researchers have developed a inexpensive transistor sensor for detection of biomolecules and other substances. Their first biosensor successfully detects the enzyme glutathione S-transferase (GST), linked to Parkinson's, Alzheimer's and breast cancer, among other diseases. The team is also developing an innovative paper-based electronic sensor to lower the cost even further. More...31 May 2016

Blood Analyses Predict Delirium Risk In Older Surgical Patients
Delirium, or sudden severe confusion due to rapid changes in brain function that can occur with physical or mental illness, affects 15% to 53% of older surgical patients and has been linked with longer hospital stays, greater postoperative complications, and higher rates of discharge to nursing homes. More...26 May 2016

New Gene Associated With Familial High Cholesterol
The gene that explains one quarter of all familial hypercholesterolemia with very high blood cholesterol has been revealed. Familial hypercholesterolemia is the most common genetic disorder leading to premature death, found in 1 in 200 people. More...26 May 2016

Elevated Chitotriosidase Differentially Diagnoses Lysosomal Storage Disorders
Plasma chitotriosidase originates from activated macrophages and is reported to be elevated in many Lysosomal Storage Disorders. Measurement of this enzyme’s activity has been an available tool for monitoring therapy of Gaucher disease. More...25 May 2016

Microfluidic Chip Developed For Ultrasensitive Glucose Detection
Highly sensitive and rapid detection of blood glucose is a diagnostic necessity in medicine as, for instance, lack of insulin and too much blood sugar are two main causes of diabetes, both of which can be detected by measuring blood glucose. More...18 May 2016
In Other News
Infrared Technology Used To Screen For Minimally Invasive Colitis
Newborn Screening Test Developed For Deadly Neurological Disorder
Breath Test May Help Diagnose Irritable Bowel Syndrome
Blood Test Detects Breast Cancer Spread Earlier
Blood Test Developed for Parkinson’s Disease
New Approach Improves Identification of Women at High Risk of Preeclampsia
Plasma Levels Investigated as Alzheimer's Disease Biomarkers
Liver Cancer May Be Diagnosed from Altered Sugar Metabolism
Highly Sensitive Detection Method Monitors HDL Kinetics
Simple Blood Test Can Detect Injury and Mild Concussion
Novel Method Detects Bacterial Infection in Preterm Infants
Test Predicts Death in Patients with Serious Liver Disease
Wearable Biomedical Device Helps Combat Diabetes
Link Found Between Brain Metabolism and Fluid Intelligence
Novel Blood Test Developed for Alzheimer's Diagnosis
Blood Test Detects Chronic Traumatic Encephalopathy During Life
Diabetes Testing on High-Throughput Analyzer Files for FDA Approval
Low Vitamin D Predicts Aggressive Prostate Cancer
Elevated C-Reactive Protein Found in H7N9 Influenza Infection
Biomarker Identified for Early Cognitive Decline in Parkinson's Disease
Higher Histone Levels Associated with Thrombocytopenia
Lipidomics Method Could Bring Fast Cancer Diagnosis
Biomarkers Help Diagnose Mild Cognitive Impairment in Diabetics
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.