Clinical Chemistry
Proteome-Based Marker Classifies Chronic Kidney Disease Progression
Chronic kidney disease (CKD) progression is currently assessed by a decline in estimated glomerular filtration rate (eGFR) and/or an increase in urinary albumin excretion (UAE) though these markers are considered either to be late-stage markers or to have low sensitivity or specificity. More...26 Jul 2016
Exposure to Toxins in Children Associated with Kidney Disease Biomarker
Researchers have assessed environmental exposure to multiple toxins in children living in a region of Mexico with a high incidence of chronic kidney disease, especially among young adults. They not only detected high levels of arsenic and chromium in urine samples, they also detected elevated levels of Kidney Injury Molecule-1 (KIM-1), a biomarker currently being studied as an early sign of kidney injury. More...26 Jul 2016
Common Circulating Cell Clusters in Cancer Patients Characterized Anew
In a study of blood samples from colorectal cancer patients, researchers have now discovered the source of these cells and that they are not malignant, potentially opening up a new path to detect and inhibit the spread of cancer. More...25 Jul 2016
Low Selenium Levels Linked to Liver Cancer Development
Selenium is a trace mineral micronutrient that is found in foods like shellfish, salmon, Brazil nuts, meat, eggs, grains, and onions. However, selenium levels in foods depend largely on the levels of selenium in the soil where the food is grown and animals graze. More...21 Jul 2016
Lipoprotein-Associated Phospholipase A2 Tests Help Diagnose Heart Disease
The measurement of low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (non-HDL-C) is currently the mainstay when assessing the risk of atherosclerosis leading to cardiovascular disease. More...19 Jul 2016
Heart Transplantation Recipients Unaffected by Donor Troponin Levels
Many transplant centers routinely reject hearts if the donor’s blood test reveals elevated levels of troponin I, a protein found in heart muscle that enters the bloodstream when there is a heart attack or other heart muscle damage. Donors with previous heart disease are automatically excluded. More...14 Jul 2016
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Testosterone Reference Ranges Vary Widely in Medical Laboratories
Reproducibility Of Stored Serum Potassium Values Analyzed
Urinary Round Cells Predict Need For Hemodialysis
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Handheld Device Detects Heart Attacks
Blood Metabolites Tests Helps Tailor Cancer Treatment
Urinary Biomarkers Diagnose Preeclampsia
Blood Test Uncovers Undiagnosed Diabetes In Hospital Patients
New Therapies for Parkinson’s Disease More Effective at Early Stages of Diagnosis
Chemosensor Detects Cancer Biomarker Neopterin
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Bioelectronic Device Detects Marker Linked to Neurodegenerative Diseases and Cancer
Blood Analyses Predict Delirium Risk In Older Surgical Patients
New Gene Associated With Familial High Cholesterol
Elevated Chitotriosidase Differentially Diagnoses Lysosomal Storage Disorders
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.