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Clinical Chemistry

Image: The Advia Centaur XP immunoassay analyzer (Photo courtesy of Siemens Healthcare).

Relationship of Serum Cortisol and Serum Sodium Analyzed

Hyponatremia is the most common electrolyte disorder encountered by the clinical biochemist, and is associated with a significant mortality and hypernatremia is also a risk factor for mortality in critically ill patients. More...
19 Jul 2017
Image: The 96.96 Dynamic Array IFC for Gene Expression, which enables 9,216 reactions using 96 samples and assay (Photo courtesy of Fluidigm).

Ultra-Early Inflammatory Biomarker Identified for TBI

Traumatic brain injury (TBI) is set to become the leading cause of neurological disability across all age groups. Currently, no reliable biomarkers exist to help diagnose the severity of TBI to identify patients who are at risk of developing secondary injuries. More...
18 Jul 2017
Image: A scanning electron micrograph (SEM) of ovarian cancer cells (Photo courtesy of SPL).

MALDI-TOF-MS Analysis Identifies Ovarian Cancer Patterns

Ovarian cancer (OC) is one of the leading causes of death among all gynecological malignancies and as there are no early specific symptoms, OC is diagnosed in advanced clinical stages in more than 70% cases when, despite appropriate treatment, five-year survival rate drops to 30%. More...
18 Jul 2017
Image: Research being conducted uses an atmospheric-pressure glow discharge plasma to probe samples for elemental and molecular species, and could lead to user-friendly MS analyses with broad capabilities (Photo courtesy of the Rensselaer Polytechnic Institute).

Mass Spectrometry Detection for the Masses

Researchers are developing a plasma-based technology to enable generalized use of mass spectrometry (MS) with new instruments that can analyze a much broader range of molecular species than current technology allows. More...
17 Jul 2017

Opioid-Related Deaths Possibly Prevented By Gene Testing

More than 17,500 Americans died in 2015 from prescription opioid overdoses, which are more than quadruple the amount of people who died from this cause in 1999, but it is not just abuse of these medications that can lead to overdoses. More...
11 Jul 2017
Image: The wearable diagnostic biosensor that can detect three interconnected, diabetes-related compounds, cortisol, glucose and interleukin-6, in perspired sweat for up to a week without loss of signal integrity (Photo courtesy of the University of Texas at Dallas).

Wearable Tool Created for Monitoring Diabetes

A wearable diagnostic biosensor has been developed that can detect three interconnected compounds, cortisol, glucose and interleukin-6, in perspired sweat for up to a week without loss of signal integrity. More...
05 Jul 2017
Image: Benign pancreatic mucinous cystic neoplasm (Photo courtesy of Wikipedia).

Combined Molecular Test Distinguishes Benign Pancreatic Lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. Serous cystic neoplasms (SCNs) have no malignant potential, but can mimic the following premalignant mucinous cystic lesions: mucinous cystic neoplasm and intraductal papillary mucinous neoplasm (IPMN). More...
05 Jul 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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