Clinical Chemistry

Single-Cell Diagnostics Advocated for Breast Cancer Subtyping
In an opinion article based their analysis of studies, two medical researchers argue that women diagnosed with breast cancer (BC) would likely benefit from treatment based also on identifying the molecular subtype of different cells within their tumors, in addition to current molecular and histopathology testing of collections of tumor cells. More...06 Nov 2017

Genetic Mutation Linked to New Form of Diabetes
Finding the genetic cause of rare familial diabetes (monogenic diabetes) provides new biological insights into human pancreas development and function, as well as potentially novel therapeutic targets with important treatment implications. More...02 Nov 2017

Experts Recommend Fewer Tests for Hospitalized Patients
Routine daily laboratory testing of hospitalized patients reflects a wasteful clinical practice that threatens the value of health care. Initiatives from numerous professional societies have identified repetitive laboratory testing in the face of clinical stability as low value care. More...31 Oct 2017



Ovarian Reserve Tests Prove Poor Predictors of Fertility
Tests that measure a woman’s “ovarian reserve” to estimate how many more years of fertility she has have grown increasingly popular, yet despite the lack of evidence of their utility, biomarkers of ovarian reserve are being promoted as potential markers of reproductive potential. More...24 Oct 2017

Low Serum Calcium Increases Risk of SCA
Sudden cardiac arrest (SCA) is fatal for over 90% of patients, and more than half of men and close to 70% of women who die of SCA have no clinical history of heart disease prior to this cardiac event. It is one of the leading causes of death in the USA and kills more people than any single cancer. More...19 Oct 2017
In Other News
Renal Biomarker Test Prevents Acute Kidney Injury
Diagnostic Options When Standard Tests Are Inconclusive
Metabolomics Analysis Applied to Investigate MPS
Umbilical Cord Bilirubin Predicts Neonatal Jaundice
Tests for Smell Loss May Detect Alzheimer’s and PD
Monitoring System No Longer Requires Fingerstick Calibration
Serum Magnesium Levels Linked to Dementia Risk
New Urine Analyzer Evaluated for Performance
Field Evaluation of Quantitative G6PD Diagnostics Reviewed
Biomarkers Prove Role of Food for Diabetics
Pancreatic Proteins Increase Sensitivity of Type 1 Diabetes Tests
Type 2 Diabetes Misdiagnosed in African Americans
Low-Volume Aldosterone Immunoassay Validated for Small Samples
Potential Biomarkers of AMD Identified in Human Plasma
Protein Network Mutations Impact Revealed in Bowel Cancer
Cholesterol Diagnosis Related to Breast Cancer Risk
Mucin Concentration Used As Bronchitis Biomarker
Handheld Mass Spectrometer Identifies Cancer Tissue in Seconds
Various Factors Influence Cardiac Troponin Concentrations
Febrile Rhabdomyolysis Diagnosed in West African Refugees
CSF Pleocytosis Level Investigated as Diagnostic Predictor
World’s First Portable Fingerprint Drug Test Launched
Diabetes Prevalence Increased in Hospitalized Patients
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.