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Clinical Chemistry

Image: An illustration of early cardiac troponin kinetics in patients after acute myocardial injury including acute myocardial infarction (Photo courtesy of ESC Scientific Document Group).

Blood Tests Differentiate Myocardial Injury from Infarction

Myocardial infarction represents the death of myocardial cells and is characterized by acute myocardial ischemia. Nonischemic myocardial injury by comparison is often associated with other conditions such as renal failure or heart conditions like myocarditis. More...
03 Oct 2018
Image: A pregnant woman undergoing a blood test for gestational diabetes (Photo courtesy of US National Institute of Diabetes and Digestive and Kidney Diseases).

High Blood Sugar During Pregnancy Increases Risk of Diabetes

Mothers with elevated blood glucose during pregnancy, even if not high enough to meet the traditional definition of gestational diabetes, were significantly more likely to have developed type 2 diabetes a decade after pregnancy than their counterparts without high blood glucose. More...
02 Oct 2018
Image: CT45, a biomarker marker found in some ovarian cancer cells, is associated with extended disease-free survival for women with advanced ovarian cancer (Photo courtesy of University of Chicago Medical Center).

Ovarian Cancer Biomarker Predicts Therapy Response

Despite months of aggressive treatment involving surgery and chemotherapy, about 85% of women with high-grade widespread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15% of patients, however, do not have a recurrence and most of those women remain disease free for years. More...
01 Oct 2018
Image: The Aperio Scanscope XT slide scanner (Photo courtesy of University of New South Wales).

Nano-LCMS Differentiates Liver Diseases

Non-alcoholic steatohepatitis (NASH) is among the leading causes of liver disease worldwide. It is increasingly recognized that the phenotype of NASH may involve a number of different pathways, of which each could become important therapeutic targets. More...
24 Sep 2018
Image: High-sensitivity troponin I assays (TnIH) for the Atellica IM and ADVIA Centaur XP/XPT in vitro diagnostic analyzers to aid in the early diagnosis of myocardial infarctions (Photo courtesy of Siemens Healthineers).

High-Sensitivity Cardiac Troponin I Assay Validated

Myocardial infarction (MI), commonly known as a heart attack occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. More...
20 Sep 2018
Image: High magnification micrograph of senile cardiac amyloidosis from an autopsy specimen (Photo courtesy of Nephron).

Novel Biomarkers Predict CV Events in Type 2 Diabetes

Cardiovascular disease generally refers to conditions that involve narrowed or blocked blood vessels that can lead to a heart attack, chest pain (angina) or stroke. Cardiovascular disease (CVD) risk prediction represents an increasing clinical challenge in the treatment of diabetes. More...
20 Sep 2018
Image: Immunostaining of Helicobacter pylori infection in the small intestine. The small spiral-curved shaped bacterium can be seen clearly using a ×100 oil objective under the microscope (Photo courtesy of BioCare Medical).

Tumor Markers Associated with H. Pylori Infection

Helicobacter pylori infection is a major cause of several cancers such as gastric, pancreatic and lung. The relationship between H. pylori and tumor markers continues to remain unclear. As one of the leading causes of morbidity and mortality globally, cancer represents a major detrimental public health problem worldwide. More...
19 Sep 2018
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.