Clinical Chemistry

Low Testosterone Men Less Likely to Have Prostate Cancer
Prostate cancer affects more than 170,000 men each year in the USA, of who almost 30,000 die from the disease. While it is not yet known what causes the condition, a number of risk factors have been identified, such as age, ethnicity, and genetic mutations. More...24 Nov 2017


Fecal Zonulin Elevated in Crohn’s Disease and Smokers
Human zonulin is a protein that increases permeability in the epithelial layer of the small intestine by reversibly modulating the intercellular tight junctions. There is not sufficient information available about zonulin's participation in inflammatory bowel diseases (IBD). More...20 Nov 2017

Urine Particle Analyzer Compared with Standard Methods
Urinary tract infections (UTIs) are characterized by the presence of microbial pathogens within the urinary tract, and they represent one of the most common infections identified in both hospitalized and clinic patients. Most UTIs are easily treated without difficulty. More...20 Nov 2017

New Methods Developed to Diagnose TB and HIV
The bacteria responsible for tuberculosis (TB) can lurk in a person's lung tissue for decades before producing active, infectious TB disease and it is estimated that a third of the global population may have such dormant infections, with 5% to 10% progressing to active disease. Detecting TB is notoriously challenging. More...15 Nov 2017

High Thyroid Hormone Levels Associated with Arterial Disease
Atherosclerosis is the process of progressive thickening and hardening of the walls of arteries from fat deposits on their inner lining. Atherosclerosis progresses insidiously from a subclinical condition to the clinical onset of vascular events to death. More...15 Nov 2017

Potential Autoantigen Identified in Aggressive Kidney Disease
Fibrillary glomerulonephritis (FGN) is an aggressive kidney disease, and nearly half of patients become dependent on dialysis within several years of diagnosis. No unique clinical markers of FGN have been identified to help diagnose FGN, and current tests involve time-consuming analyses with light microscopy, immunofluorescence, and electron microscopy. More...13 Nov 2017
In Other News
Fecal Calprotectin Predicts Complete Mucosal Healing in UC
FIT Hemoglobin Predicts Risk of Advanced Neoplasia
Blood Test Can Effectively Rule Out Breast Cancer
Single-Cell Diagnostics Advocated for Breast Cancer Subtyping
Genetic Mutation Linked to New Form of Diabetes
Experts Recommend Fewer Tests for Hospitalized Patients
Fecal Hemoglobin Stability Evaluated for FITs
Risk Factors Identified for Duchenne Muscular Dystrophy-Associated Cardiomyopathy
Ovarian Reserve Tests Prove Poor Predictors of Fertility
Low Serum Calcium Increases Risk of SCA
Renal Biomarker Test Prevents Acute Kidney Injury
Diagnostic Options When Standard Tests Are Inconclusive
Metabolomics Analysis Applied to Investigate MPS
Umbilical Cord Bilirubin Predicts Neonatal Jaundice
Tests for Smell Loss May Detect Alzheimer’s and PD
Monitoring System No Longer Requires Fingerstick Calibration
Serum Magnesium Levels Linked to Dementia Risk
New Urine Analyzer Evaluated for Performance
Field Evaluation of Quantitative G6PD Diagnostics Reviewed
Biomarkers Prove Role of Food for Diabetics
Pancreatic Proteins Increase Sensitivity of Type 1 Diabetes Tests
Type 2 Diabetes Misdiagnosed in African Americans
Low-Volume Aldosterone Immunoassay Validated for Small Samples
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.




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