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Clinical Chemistry

Image: A piezoelectrically actuated pipette system is used as an inexpensive means to detect biological molecules associated with specific diseases, infection or other medical conditions (Photo courtesy of Purdue University).

Blood Biomarker Detected for Different Diseases

A method has been developed to identify biological markers in small amounts of blood that could be used to detect a myriad of diseases, infections and different medical conditions at early stages. More...
05 Dec 2017
Image: A histological section showing a obstructed extrahepatic bile duct. It exhibits residual expression of the enzyme called MMP-7 (shown in brown) (Photo courtesy of Cincinnati Children\'s Hospital Medical Center).

Diagnostic Test Identified for Pediatric Biliary Atresia

Biliary atresia is a rare disease of the liver and bile ducts that occurs in infants. Liver cells produce bile, which helps digest fat and carries waste products from the liver to the intestines. When an infant has biliary atresia, this flow is blocked and bile becomes trapped inside the liver, quickly causing liver damage and eventually liver failure. More...
05 Dec 2017
Image: The Access Hybritech new p2PSA test, part of the Prostate Health Index (phi) (Photo courtesy of Beckman Coulter).

Physicians Perform Fewer Prostate Biopsies Post-Phi Testing

Prostate cancer is the third-leading cause of cancer death in men, with one in seven receiving a diagnosis during his lifetime. In 2017, approximately 161,360 new cases of prostate cancer were identified, with 60% of those occurring in men 65 years of age or older. More...
04 Dec 2017
Image: The ARCHITECT i2000SR immunoassay analyzer (Photo courtesy of Abbott).

Newly Developed Automated Immunoassay Analyzed

Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted treatments. More...
29 Nov 2017
Image: A histopathology of extensive hepatocyte necrosis seen here in a case of paracetamol overdose. The hepatocytes at the right are dead, and those at the left are dying. This pattern can be seen with a variety of hepatotoxins (Photo courtesy of the University of Utah Medical School).

Test Detects Overdose Patients at Risk of Liver Damage

Paracetamol is a safe analgesic drug when taken at therapeutic doses; however, in overdose, paracetamol is hepatotoxic and is the most common cause of acute liver failure in the USA and Europe. More...
28 Nov 2017
Image: Diagram of DiviTum sTK1 assay: BrdUTP is subsequently incorporated into a solid-phase DNA-strand. Incorporated BrdU is detected using an anti-BrdU monoclonal antibody conjugated to the signal generating enzyme alkaline phosphatase. The level of BrdU incorporated over time is proportional to the level of thymidine kinase activity in the sample (Photo courtesy of Biovica).

Blood Test Reduces Interim for Evaluating Cancer Treatment

Although prognosis and treatment of metastatic breast cancer (MBC) have improved over the last years, there is still an unmet clinical need for more precise prognostic and treatment monitoring tools. More...
27 Nov 2017
Image: A scanning electron photomicrograph (SEM) of prostate cancer cells (Photo courtesy of Prostate Cancer UK).

Low Testosterone Men Less Likely to Have Prostate Cancer

Prostate cancer affects more than 170,000 men each year in the USA, of who almost 30,000 die from the disease. While it is not yet known what causes the condition, a number of risk factors have been identified, such as age, ethnicity, and genetic mutations. More...
24 Nov 2017
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Quantitative POC Immunoassay Analyzer
EASY READER+
POC Helicobacter Pylori Test Kit
Hepy Urease Test
Automated Chemiluminescence Immunoassay Analyzer
MS-i3080
Sperm Quality Analyis Kit
QwikCheck Beads Precision and Linearity Kit

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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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