Clinical Chemistry

High Thyroid Hormone Levels Associated with Arterial Disease
Atherosclerosis is the process of progressive thickening and hardening of the walls of arteries from fat deposits on their inner lining. Atherosclerosis progresses insidiously from a subclinical condition to the clinical onset of vascular events to death. More...15 Nov 2017

Potential Autoantigen Identified in Aggressive Kidney Disease
Fibrillary glomerulonephritis (FGN) is an aggressive kidney disease, and nearly half of patients become dependent on dialysis within several years of diagnosis. No unique clinical markers of FGN have been identified to help diagnose FGN, and current tests involve time-consuming analyses with light microscopy, immunofluorescence, and electron microscopy. More...13 Nov 2017

Fecal Calprotectin Predicts Complete Mucosal Healing in UC
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) characterized by a disease course involving relapses and remissions. Historically, clinical remission was the major treatment target for patients with UC. More...13 Nov 2017


Blood Test Can Effectively Rule Out Breast Cancer
Breast density is associated with reduced imaging resolution in the detection of breast cancer. Breast density is a radiologic phenomenon that is not discernable by palpation; it is a radiologist’s assessment. Imaging rays permeate dense breast tissue in a more opaque manner, thereby reducing image resolution. More...07 Nov 2017

Single-Cell Diagnostics Advocated for Breast Cancer Subtyping
In an opinion article based their analysis of studies, two medical researchers argue that women diagnosed with breast cancer (BC) would likely benefit from treatment based also on identifying the molecular subtype of different cells within their tumors, in addition to current molecular and histopathology testing of collections of tumor cells. More...06 Nov 2017

Genetic Mutation Linked to New Form of Diabetes
Finding the genetic cause of rare familial diabetes (monogenic diabetes) provides new biological insights into human pancreas development and function, as well as potentially novel therapeutic targets with important treatment implications. More...02 Nov 2017
In Other News
Experts Recommend Fewer Tests for Hospitalized Patients
Fecal Hemoglobin Stability Evaluated for FITs
Risk Factors Identified for Duchenne Muscular Dystrophy-Associated Cardiomyopathy
Ovarian Reserve Tests Prove Poor Predictors of Fertility
Low Serum Calcium Increases Risk of SCA
Renal Biomarker Test Prevents Acute Kidney Injury
Diagnostic Options When Standard Tests Are Inconclusive
Metabolomics Analysis Applied to Investigate MPS
Umbilical Cord Bilirubin Predicts Neonatal Jaundice
Tests for Smell Loss May Detect Alzheimer’s and PD
Monitoring System No Longer Requires Fingerstick Calibration
Serum Magnesium Levels Linked to Dementia Risk
New Urine Analyzer Evaluated for Performance
Field Evaluation of Quantitative G6PD Diagnostics Reviewed
Biomarkers Prove Role of Food for Diabetics
Pancreatic Proteins Increase Sensitivity of Type 1 Diabetes Tests
Type 2 Diabetes Misdiagnosed in African Americans
Low-Volume Aldosterone Immunoassay Validated for Small Samples
Potential Biomarkers of AMD Identified in Human Plasma
Protein Network Mutations Impact Revealed in Bowel Cancer
Cholesterol Diagnosis Related to Breast Cancer Risk
Mucin Concentration Used As Bronchitis Biomarker
Handheld Mass Spectrometer Identifies Cancer Tissue in Seconds
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.