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Clinical Chemistry

Image: The Architect 25-OH Vitamin D reagent kit (Photo courtesy of Abbott).

Two Vitamin D Immunoassays Compared

Vitamin D can be synthesized in skin from 7-dehydrocholesterol following ultraviolet light exposure, which produces Vitamin D3 (cholecalciferol). Vitamin D2 (ergocalciferol) is present in plant sources, and can be absorbed from the diet. More...
20 Aug 2019
Image: A histopathology of pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer, arising in the pancreas head region (Photo courtesy of KGH).

Pancreatic Cancer Risk Rises with Fasting Glucose

More than 56,000 Americans are expected to be diagnosed with pancreatic cancer in 2019, which is more than 150 people diagnosed every day. Pancreatic cancer is the ninth most commonly diagnosed cancer in women and the 10th most commonly diagnosed in men in the USA. More...
15 Aug 2019
Image: The GeneXpert MTB/RIF assay is designed as a rapid diagnosis test of Tuberculosis (TB) and drug resistance (Photo courtesy of Cepheid).

Serum Siderocalin Measured in Patients with TB and HIV

Tuberculosis (TB) continues to be a significant cause of morbidity and mortality worldwide. The progression from uninfected or latently infected to active TB is often insidious and has minimal symptoms in the initial months, resulting in delayed diagnosis and poor outcomes. More...
14 Aug 2019
Image: The Xevo TQ-S micro Triple Quadrupole Mass Spectrometry (Photo courtesy of Waters).

High Fetal Estrogen Levels Linked to Autism

The male-biased prevalence of autism, together with the finding that autistic girls have a higher mutational load than autistic boys, suggests that males have a higher likelihood of developing autism. More...
13 Aug 2019
Image: Scientists determined that one-third of total cholesterol in plasma was present in remnant lipoproteins, which is in the triglyceride-rich lipoproteins intermediate-density lipoprotein (IDL) and very low-density lipoprotein (VLDL) (Photo courtesy of Harvard Medical School).

High Remnant Particle Cholesterol Levels Profiled in Blood

Three quarters of the Danish population have moderately elevated levels of cholesterol. If cholesterol levels are too high, risk of cardiovascular disease is increased. Often, low-density lipoprotein (LDL) cholesterol, the so-called bad cholesterol, is considered the culprit. More...
13 Aug 2019
Image: The cobas e 801 module is a high throughput immunochemistry module that performs a broad range of heterogeneous immunoassay tests (Photo courtesy of Roche Diagnostics).

Low Serum IGF1 Predicts CV Events in RA Women

Hypertension is a significant health threat and an independent predictor of cardiovascular (CV) events including coronary heart disease, stroke, heart failure, and dementia in the general population and in rheumatoid arthritis (RA). More...
06 Aug 2019
Image: The Tosoh Automated Glycohemoglobin Analyzer G8, designed for rapid and reliable diabetic monitoring and diagnosis (Photo courtesy of Tosoh).

Different Biochemical Parameters Found in Patients with IGR

Diabetes is a chronic metabolic disease due either to a lack of insulin secretion or reduced insulin sensitivity, with high blood sugar levels being the main characteristic and is often associated with fat, protein and electrolyte metabolic disorders and acid-base imbalance. More...
06 Aug 2019
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.