Clinical Chemistry
Genetic Scores Stratify Risk of Developing Type 1 Diabetes
Approximately 0.3% of newborns will develop autoimmunity to pancreatic beta cells in childhood and subsequently develop type 1 diabetes before adulthood. Primary prevention of type 1 diabetes will require early intervention in genetically at-risk infants. More...15 May 2018
ACTH Stimulation Test Results Reassessed
Cosyntropin (adrenocorticotropic hormone or ACTH) stimulation testing is considered the gold standard for investigating primary adrenal insufficiency (AI) and may be an effective alternative to insulin tolerance testing in the workup of secondary AI. More...12 May 2018
Subthreshold Amyloid Predicts Tau Deposition in Aging
The progressive nature of Alzheimer's disease (AD) necessitates the earliest possible detection of pathological or cognitive change if disease progression is to be slowed. The rate at which the protein beta-amyloid (Aβ) accumulates into the sticky plaques associated with Alzheimer's disease (AD) is already slowing by the time a patient would be considered to have preclinical AD. More...10 May 2018
Biomarkers Identified for Irritable Bowel Syndrome
The causes of gastrointestinal complaints in irritable bowel syndrome (IBS) remain poorly understood. Altered nerve function has emerged as an important pathogenic factor as IBS mucosal biopsy supernatants consistently activate enteric and sensory neurons. More...02 May 2018
Beta-Amyloid Dimers Found in Alzheimer's Patient Brains
The most widely used biomarkers for the early detection of Alzheimer's disease (AD) are currently the concentrations of beta-amyloid (Aβ) and phosphorylated Tau in cerebrospinal fluid. However, it has been observed that not all individuals with alterations in these biomarkers develop the disease. More...01 May 2018
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In Other News
Low Total Testosterone Linked to Chronic Disease
Continuous Glucose Monitor Benefits Diabetics
BTP Viewed As Glomerular Filtration Rate Marker
Vitamin D Blood Test May Speed Pediatric Bipolar Diagnosis
Amyloid Blood Biomarker Detects Alzheimer's Disease
CV Biomarkers Associated with Incident Heart Failure
Interoperable Glucose Monitoring System Authorized
Liquid Biopsy Can Rule Out Early-Stage Lung Cancer
Chronic Fatigue Syndrome Linked to Thyroid Levels
Biomarker Assay Recommended for Heart Failure Diagnosis
CKD May Occur Before Diabetes Diagnosis
New Heart Attack Test Better Informs Underlying Condition
Omega-3 Levels Predict Death Risk Better Than Serum Cholesterol
Alzheimer Disease CSF Biomarker Used in Clinical Setting
CO-Oximetry External QA Programme Launched
CRP Levels May Indicate Schizophrenia Prognosis
Troponin I Levels Predict Coronary Artery Disease Severity
Novel Biomarkers Revealed for Future Dementia Risk
Dried Blood Spot Protein Assays Evaluated for Biochemistry
Biological Markers in Tears May Diagnose PD
Plasma Metabolite Profile and Gut Microbiota Connected to Obesity
Parent Age May Help Predict AD Biomarker Levels
Blood Test Biomarkers Diagnose Autism Accurately
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.