Clinical Chemistry

New Technique Predicts Preterm Births in High Risk Women
Globally, preterm birth is the leading cause of death in children under 5 years with 15 million babies being born before 37 weeks’ gestation each year. Spontaneous preterm birth is a syndrome, which can be precipitated by a variety of factors. More...14 Aug 2020

Dolichol Biomarker Evaluated for Congenital Disorders of Glycosylation
A congenital disorder of glycosylation (CDG; previously called carbohydrate-deficient glycoprotein syndrome) is one of several rare inborn errors of metabolism in which glycosylation of a variety of tissue proteins and/or lipids is deficient or defective. More...14 Aug 2020

Simple Urine Test Significantly Improves Detection of Adrenal Cancer
Prognosis for patients discovered to have an adrenal cortical carcinoma (ACC), a cancerous adrenal mass, is poor, and a cure is only achievable through early detection and surgery. The incidental discovery of an adrenal mass often triggers additional scans to determine whether the mass is cancerous. More...06 Aug 2020

Lipocalin 2 Proposed as Biomarker for Bacterial Meningitis
Central nervous system (CNS) infections cause significant mortality and morbidity worldwide. Common CNS infections include bacterial meningitis (BM) other than tuberculosis, viral encephalitis, tuberculous meningitis (TBM) and cryptococcal meningitis, but there are more than 100 documented infectious causes of CNS infections. More...05 Aug 2020

Protracted Ketonemia Reported in Hyperglycemic COVID-19 Emergencies
Diabetes is a major contributor to disease severity and mortality in patients with COVID-19; with an estimated 3.5-times increase in risk of death during hospital admission for patients with type 1 diabetes, and 2.03-times for those with type 2 diabetes. More...03 Aug 2020

Plasma Lipidome Investigated in Hereditary Hemochromatosis
Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption which leads to iron overload and consequently to tissue damage and functional impairment of organs like liver, pancreas, and heart. More...28 Jul 2020

In Other News
Melatonin Levels in Parkinson’s Patients Linked to Non-Motor Symptoms
Blood Tests Predicts the Risk of Liver Cirrhosis
Fully-Automated Calprotectin Immunoassay Validated for IBD Patients
Geochemistry Test Identifies Osteoporosis Earlier Than Standard Method
Pediatric CKD Progression Linked to Low Serum Bicarbonate
Presepsin Values Evaluated as Sepsis Severity Markers
Pregnancy TSH Variations Prompt Erroneous Thyroid Disease Diagnosis
Biomarkers Evaluated for Lung Disease Severity in Cystic Fibrosis
Metabolite Profiling Reveals Predictive Biomarkers for Amyotrophic Lateral Sclerosis
Serum Free Thiols Predict Cardiovascular Events
Urine Testing Method Developed for Ureterolithiasis
Glucose Levels Linked to Maternal Mortality Even in Non-Diabetic Women
Endogenous Testosterone Levels Associated with Risk of Diabetes
Biomarkers Evaluated in Children with Community-Acquired Pneumonia
Elevated Metal Ion Level Detects Defective Hip Arthroplasty Implants
Soluble Transferrin Receptor Investigated in Iron Deficiency Anemia
Biomarker Data Improves Risk Prediction for Pancreatic Cancer
Blood Biomarkers Help Diagnose Parkinson's Disease
Salivary Molecular Spectroscopy Used to Monitor Diabetes
Biomarker Panel Evaluated for Primary Hyperoxaluria Patients
HPLC Method Developed for Vitamin B6 Quantitation
Elevated Vitamin-B12 Level Lowers Risk of Parkinson’s Disease Dementia
Novel Glycoprotein Biomarker Evaluated for Liver Fibrosis
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.