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BioResearch

Image: A computer-generated model of the surface of an alphavirus derived by cryoelectron microscopy. Alphaviruses are RNA-containing viruses that cause a wide variety of mosquito-transmitted diseases (Photo courtesy of the [US] Centers for Disease Control and Prevention (CDC)).

Viral siRNA Carriers Key to Powerful New Gene Silencing Technique

A screening technique based on viruses modified to carry discrete gene-silencing small interfering RNA molecules is being employed to follow the interaction between viruses and their natural host cells. More...
25 Sep 2013
Image: Leaves of the medicinal plant Gymnema sylvestre (Photo courtesy of Wikimedia Commons).

Gymnemic Acids Stabilize the Yeast Form of Candida albicans and Enhance Action of Antifungal Drugs

Small molecules isolated and purified from leaves of Gymnema sylvestre inhibit yeast-to-hypha conversion and hyphal growth in the fungus Candida albicans, which greatly enhances the effect of antifungal drug treatments. More...
24 Sep 2013

Nanodiamond System Used to Deliver Chemotherapy Directly to Brain Tumors

Scientists have devised a new drug delivery system using nanodiamonds that allows direct application of chemotherapy to brain tumors with fewer harmful side effects and better cancer-killing efficiency than existing treatments. More...
24 Sep 2013
Image: Subretinal hemorrhage in a wet macular degeneration patient (Photo courtesy of Chavala Laboratory, University of North Carolina).

Nutlin-3 Shows Promise for Treating Macular Degeneration

A low molecular weight drug, Nutlin-3, prevented growth of new blood vessels in cell cultures and in a mouse model and may prove to be the treatment of choice for macular degeneration. More...
23 Sep 2013

Nanostring Technique Identifies Potential Melanoma Immunotherapy Targets

An advanced "nanostring" DNA expression analysis technique detected seven genes that are potential immunotherapy targets for the treatment of melanoma and could increase the number of patients potentially eligible for adoptive immunotherapy. More...
23 Sep 2013

Compound Found to Reverse Down Syndrome-Like Learning Deficits in Mice

Researchers have identified a compound that dramatically boosts memory and learning when administered to mice with a Down syndrome-like disorder on the day of their birth. More...
23 Sep 2013
Image: By lowering the expression of a single gene, called mTOR, scientists have extended the average lifespan of a group of mice by about 20% (Photo courtesy of the US National Institutes of Health’s (NIH) National Heart, Lung, and Blood Institute (NHLBI)).

Mouse Lifespan Increased 20% by Single Gene Alteration

By lowering the expression of a single gene, US researchers have extended the average lifespan of a group of lab mice by about 20%—the equivalent of raising the average human lifespan by 16 years, from 79 to 95. More...
19 Sep 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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