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BioResearch

US Project Adds Extensive Range of Genetic, Health Information to Online Database

Genetic data related to medical information on a diverse group of more than 78,000 individuals will now be accesible to researchers, enabling comprehensive research into many diseases and conditions.   More...
17 Mar 2014
Image: X-ray scan of biologic cells: Each pixel represents a complete diffraction image. The color indicates how strong the X-rays are scattered at this local point (Photo courtesy of Britta Weinhausen, the University of Göttingen).

Researchers Employ High-Energy X-Ray to Image Living Cancer Cells

Scientists have performed the first studies of living biologic cells using high-energy X-rays. In the future, the new technique should make it possible to study unaltered living cells at high resolution.    More...
13 Mar 2014
Image: Photonic resonance energy transfer described by Förster, or FRET, occurs when two small proteins come within a very small distance of each other, i.e., 8 nm or less. The fluorescence lifetime of the donor molecule will become shorter—from 3 nanosecond to, possibly, 2.5 nanoseconds. The researchers then interpret this as evidence that the two proteins of interest are physically interacting with each other in a molecular signaling event (Photo courtesy of Akira Chiba/University of Miami).

Live Imaging Reveals the Brain’s Protein Interactions

For the first time, a group of scientists has been able to observe intact interactions between proteins, directly in the brain of a live animal.  More...
13 Mar 2014
Image: In order to overcome the known limitations inherent to chemical conjugation of small molecule toxic drugs to antibodies, NBE-Therapeutics has developed a patent-pending technology for the specific enzymatic conjugation of drugs to antibodies (Photo courtesy of NBE-Therapeutics).

New Technology Generates Cancer Killing Antibody Drug Conjugates

A novel technology for generation of specific toxin-bearing antibodies for treatment of cancer has been validated in a recent series of proof-of-concept studies.  More...
11 Mar 2014
Image: The number of leukemia cells (red) was greatly reduced in treated (right) vs. untreated (left) mice while sparing any significant damage to normal blood cells (black) (Photo courtesy of the Rockefeller University Press).

Shutting Down Multiple DNA Synthesis Pathways Cures Leukemia in Mouse Model

Drug treatment that combined inhibitors of both the de novo and salvage pathways for DNA synthesis cured acute lymphoblastic leukemia in a mouse model of the disease.  More...
10 Mar 2014

Gene Linking Intelligence to Brain Structure Identified

For the first time, British scientists have linked a gene associated with the thickness of the gray matter in the brain to intelligence.   More...
10 Mar 2014
Image: Highly aligned nanofibers created by fibroblasts form biological scaffolding that could prove an ideal foundation for engineered tissues. Stem cells placed on the scaffolding thrived, and it had the added advantage of provoking a very low immune response (Photo courtesy of Dr. Feng Zhao, Michigan Technological University).

Highly Aligned Nanofibers Developed for Tissue Engineering Applications

A team of biomedical engineers has constructed a uniform highly aligned nanoscale fibrous scaffolding from extracellular matrix naturally deposited by fibroblasts to be used for potential tissue engineering applications.  More...
10 Mar 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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