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BioResearch

Image: To adhere to catheters and start urinary tract infections, bacteria extend microscopic fibers with sticky proteins at their ends. Researchers have developed a vaccine that blocks the EbpA protein, visible as a white bulge above, and stops infections in mice (Photo courtesy of Dr. John Heuser, Washington University School of Medicine).

Blocking Binding of Bacteria to Fibrinogen Prevents Biofilm Formation and Catheter-Associated Bladder Infection in Mice

A team of molecular microbiologists has identified and targeted a critical step in biofilm formation and developed a vaccine that prevents catheter-associated urinary tract infections in mice.  More...
30 Sep 2014
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Advanced Temperature Controller for Microfluidic Devices for Biotech Research Introduced

An innovative temperature controller for use in microfluidic applications is available for use by biotech and other life science researchers.  More...
30 Sep 2014
Image: From the electron microscope image of nanocrystals—here, a magnesium oxide nanocrystal— below, the three-dimensional structure is reconstructed with atomic precision using a new method developed by researchers from Jülich and Xi’an. The red spheres represent magnesium, the blue, oxygen (Photo courtesy of Forschungszentrum Jülich).

Electron Microscopy Advance Rebuilds Third Dimension from Just One Image

Scientists have developed a new nanotechnology strategy with which crystal structures can be reconstructed with atomic precision in all three dimensions.  More...
30 Sep 2014
Image: Illustration of the apoER2 receptor protein shows the structure of the entire protein in detail (Photo courtesy of Wikimedia Commons).

Risk of Cardiovascular Disease Linked to Apolipoprotein E Variants

The apoE4 variant form of circulating apolipoprotein E leads to increased risk of cardiovascular disease by blocking binding of the normal apoE3 form to the apoliprotein E receptor 2 in the membranes of endothelial cells lining the walls of blood vessels and by interacting with the receptor without stimulating production of anti-inflammatory nitric oxide.   More...
29 Sep 2014

MicroRNA Mimic Shown to Reverse Effects of Pulmonary Fibrosis

A potential new treatment that reverses the effects of pulmonary fibrosis, a respiratory disease in which scars develop in the lungs and greatly suppress breathing, is being assessed by scientists.  More...
29 Sep 2014
Image: Formation of circRNA—in this case circMbl—competes with the process of linear splicing (Photo courtesy of The Hebrew University of Jerusalem).

New Findings Implicate Circular RNA in the Development of Neurodegenerative Diseases

A recent paper described new findings that shed light on the production and function of circular RNA molecules in animal neuronal tissue.  More...
28 Sep 2014
Image: Activating a gene called AMPK in the nervous system induces the antiaging cellular recycling process of autophagy in both the brain and intestine. Activating AMPK in the intestine leads to increased autophagy in both the intestine and brain. Matthew Ulgherait, David Walker and UCLA colleagues showed that this ‘interorgan’ communication during aging can substantially prolong the healthy lifespan of fruit flies (Photo courtesy of Matthew Ulgherait, UCLA).

Activating Gene Slows the Aging Process by “Remote Control”

Biologists have identified a gene that can delay the aging process when triggered remotely in vital organs. The life scientists, working with fruit flies, switched on a gene called AMPK, which is a major energy sensor in cells.   More...
28 Sep 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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