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BioResearch

Image: Using CRISPR to silence the E6 gene in Human Papilloma Virus, researchers were able to restart the cervical carcinoma cell\'s natural self-destruct mechanisms, including the gene p53. Similar results were obtained against the HPV-E7 gene, turning on the carcinoma\'s Rb gene (Photo courtesy of Duke University).

Gene Therapy Reactivates Cell Death Pathways in Cervical Cancer Cells

A team of molecular virologists has presented evidence demonstrating the possibility of developing anticancer therapies based on viral vectors that transfect carcinoma cells with RNA-protein complexes capable of reactivating genes in the cancer cells that cause cell cycle arrest and eventual cell death.  More...
18 Aug 2014

Evolutionary Changes Reproduced in the Lab by Manipulating Embryonic Development of Mice

Researchers have been able experimentally to reproduce in mice morphologic alterations that have taken millions of years to occur.  More...
18 Aug 2014

Global Computational Biology Sector Expected to Reach over USD 4 Billion by 2020

The global market for computational biology is expected to reach USD 4.285 billion by 2020 growing at a compound annual growth rate of 21.1%, according to new market research.  More...
17 Aug 2014
Image: Molecular tags of DNA damage are highlighted in green in blood-forming stem cells (Photo courtesy of UCSF – University of California, San Francicsco).

DNA Replication Difficulty May Be Key to Immune System Aging

People over 60 are not donor candidates for bone marrow transplantation; the immune system ages and weakens with time, making the elderly predisposed to life-threatening infection and other disorders. US researchers have now have found a reason.  More...
13 Aug 2014

Theraclone Partners with Gilead Sciences for Neutralizing HIV Antibody Technology

Theraclone Sciences, a therapeutic antibody discovery and development company, has entered into an agreement with Gilead Sciences, under which Gilead received an exclusive license to develop and commercialize products integrating Theraclone’s broadly neutralizing HIV-antibodies for therapeutic applications in HIV.   More...
13 Aug 2014
Image: Electron microscopy image of the bacteriophages investigated (Photo courtesy of the European Molecular Biology Laboratory).

Crystal Structures Define Mode of Action of Bacteriophage Endolysins

 New antibacterial agents based on bacteriophages or their endolysin enzymes have been proposed to solve the problem of the bacterium Clostridium difficile, which is becoming a serious health hazard in hospitals and healthcare institutes, due to its resistance to antibiotics. More...
13 Aug 2014

Factors in the Tumor Microenvironment Promote Cancer Growth and Metastasis

Cancer researchers have found that procancerous HSF1 drives a transcriptional program in cancer-associated fibroblasts that complements, yet is completely different from, the program it drives in adjacent cancer cells.  More...
13 Aug 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.