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BioResearch

Image: Lipopolysaccharides (LPS) are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond. They are found in the outer membrane of Gram-negative bacteria, and elicit strong immune responses in animals (Photo courtesy of Wikimedia Commons).

Elevated Levels of IgG2 Antibodies Protect Some Types of Gram-Negative Bacteria

The finding that an overabundance of a certain class of antibodies protects some bacteria from the effects of antibiotics has marked implications for our understanding of the protection generated by natural infections and for the design of vaccines, which should avoid inducing such inhibitory antibodies.  More...
27 Aug 2014
Image: A material that changes shape when heated could be used to make custom implants. The white bar is 1-cm-long (Photo courtesy of Melissa Grunlan, Texas A&M).

Shape Memory Polymer Designed to Help Reconstruct Faces

Researchers have developed a “self-fitting” material that expands with warm salt water to effectively fill bone defects, and also acts as a scaffold for new bone growth.  More...
27 Aug 2014
Image: Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells (Photo courtesy of the University of Texas, Austin).

Experimental Drug Kills Cancer Cells by Interfering with Their Ion Transport Mechanism

An experimental anticancer drug induces cells to enter a molecular pathway leading to apoptosis by skewing their ion transport systems to greatly favor the influx of chloride anions.  More...
26 Aug 2014
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Modular Design of New Microplate Reader Encourages Modification and Upgrades

Life science and biotech researchers now have available a state-of-the-art modular microplate reader with a wide range of capabilities from UV-visual absorbance to bottom fluorescence and luminescence.  More...
25 Aug 2014

Partnership Established to Decode Bowel Disease

23andMe, a personal genetics company, is collaborating with Pfizer, in which the companies will seek to enroll 10,000 people with inflammatory bowel disease in a research project designed to explore the genetic factors associated with the onset, progression, severity, and response to treatments for IBD.  More...
25 Aug 2014
Image: Liver cells regenerated in mice treated with a new drug (right) compared with a control group (center) after partial liver removal. Healthy liver cells are shown at left (Photo courtesy of Marshall et al, 2014, the Journal of Experimental Medicine).

New Drug Triggers Liver Regeneration After Surgery

Investigators have revealed that an innovative complement inhibitor decreases complement-mediated liver cell death, and actually stimulates postsurgery liver regrowth in mice.  More...
25 Aug 2014
Image: Microscopic view of a section of mouse brain shows tiny clusters of tumor cells growing along existing brain blood vessels (Photo courtesy of the University of Michigan).

Brain Tumors Grow by Tapping Preexisting Blood Vessels for Nutrients

Findings from a new study on how tumors grow and spread in the brain may cause cancer researchers to rethink treatment options based on drugs that block angiogenesis.  More...
24 Aug 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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