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BioResearch

Image: The antibody against ANGPTL4 is in the test tube, with the image of the lungs from the treated mice in the background (Photo courtesy of Nanyang Technological University).

Protein Found That Complicates Healing from Respiratory Infections

A protein has been identified that slows healing of respiratory tissues and complicates recovery from diseases such as influenza and pneumonia.  More...
08 Mar 2015
Image: Scanning electron microscopy images, taken at different magnifications, show the structure of new hydrogels made of nanoparticles interacting with long polymer chains. (Photo courtesy of Massachusetts Institute of Technology).

Nanoparticle-Based Hydrogel Liquefies Under Pressure for Delivery by Syringe

A hydrogel that liquefies under pressure but reforms as a gel when the pressure is released has been recruited as a delivery system for both hydrophobic and hydrophilic anticancer agents.  More...
04 Mar 2015
Image: Pulsed near infrared light (shown in red) is shone onto a tumor (shown in white) that is encased in blood vessels. The tumor is imaged by photoacoustic tomography via the ultrasound emission (shown in blue) from the gold nanotubes (Photo courtesy of Jing Claussen (iThera Medical, Germany)).

Gold Nanotubes Are Novel Agents for Cancer Diagnosis and Treatment

Cancer researchers have produced a highly defined class of gold nanotubes that are suitable for use in animals as in vivo imaging nanoprobes, photothermal conversion agents, and drug delivery vehicles.  More...
03 Mar 2015
Image: Typical antibodies (left) unfold in the harsh environment of the cell. Camelid antibodies (right) are smaller and more stable (Photo courtesy of the Washington University School of Medicine).

Double Targeting Approach Increases Potential for Cancer Treatment with Oncolytic Viruses

Cancer researchers have used a double targeting approach to direct oncolytic viruses specifically to tumor cells where they reproduce until the cancer cells burst, releasing more viruses to infect and ultimately destroy the tumor.  More...
02 Mar 2015
Image: Bacteriophage EFDG1 visualized by transmission electron microscopy (TEM) at a magnification of 20,000–30,000 times. Note that some phages are still bound to remains of the dead bacteria (Photo courtesy of the Hebrew University of Jerusalem).

Bacteriophage Therapy Eliminates Multidrug Resistant Bacterial Infections

Bacteriophage therapy has been shown to be an effective approach for treating infections caused by drug-resistant strains of the bacterium Enterococcus faecalis.  More...
01 Mar 2015
Image: In mice, mitochondria (green) in healthy (left) and Mfn1-deficient heart muscle cells (center) are organized in a linear arrangement, but the organelles are enlarged and disorganized in Mfn2-deficient cells (right) (Photo courtesy of the Rockefeller Press).

Cell Biologists Find That Certain Mitochondrial Diseases Stem from Coenzyme Q10 Depletion

A team of German cell biologists has linked the development of certain mitochondrial-linked diseases to depletion of the organelles' pool of coenzyme Q10 brought about by mutation in the MFN2 gene, which encodes the fusion protein mitofusin 2.  More...
25 Feb 2015
Image: Molecular model of the protein Saposin C (Photo courtesy of Wikimedia Commons).

Nanovesicles Kill Human Lung Cancer Cells in Culture and in a Mouse Xenograft Model

Nanovesicles assembled from the protein Saposin C and the phospholipid dioleoylphosphatidylserine were shown to be potent inhibitors of lung cancer cells in culture and in a mouse xenograft model.  More...
24 Feb 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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