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BioResearch

Panel of Research-Use-Only Mass-Spec Biomarker Tests Launched at AACC 2015

Over 50 research-use-only mass-spectrometry based biomarker tests, to be offered as a laboratory service, were launched during the 2015 AACC Meeting & Clinical Lab Expo. The RUO tests are specifically designed for detection and quantification of key protein biomarkers in human serum or plasma and are available to pharmaceutical companies for clinical trials, researchers, and as companion diagnostics.   More...
12 Aug 2015
Image: The Connex Objet350 3-D printer represents the current state of the art in polymer rapid prototyping systems (Photo courtesy of Stratasys Ltd.).

Neuroscience Research to Benefit from 3-D Printing of Brain-Like Structures

Advanced three-dimensional printing techniques were used to generate a biological construct that incorporated neural cells and mimicked brain cell activities for use in applications ranging from cell behavior studies to improving understanding of brain injuries and neurodegenerative diseases.   More...
12 Aug 2015
Image: Artist\'s conception of an adeno-associated viral capsid in formation by ancestral sequence reconstruction (Photo courtesy of Dr. Eric Zinn, Harvard University Medical School).

Ancient Viruses Built from Computer Models May Improve Gene Therapy Delivery

An advanced computer modeling strategy was used to design ancient forms of adeno-associated viruses, which were then synthesized in the laboratory for use as potential delivery vectors for gene therapy.  More...
11 Aug 2015

FDA Approves Rapid Dissolving Epilepsy Drug Produced by 3D Printing

A novel rapidly solubilized drug for treatment of epilepsy has become the first medication manufactured by a three-dimensional printing technique to be approved by the Food and Drug Administration.  More...
11 Aug 2015
Image: A representative image of islets from diabetic mice, which did not receive IL-35 (left) and received IL-35 (right). The brown color represents insulin producing beta cells. New research showed progress in the use of the anti-inflammatory cytokine for treatment of Type I diabetes (Photo courtesy of Dr. Kailash Singh, Uppsala University).

Insufficient Interleukin-35 Leads to Type I Diabetes in Mouse Models

Diabetes researchers have linked onset of the disease to abnormally low levels of the anti-inflammatory cytokine interleukin-35, which is produced by regulatory T cells to suppress autoimmune and inflammatory responses.  More...
10 Aug 2015
Image: Photomicrograph shows emergence of stem cell-derived hepatocytes (Photo courtesy of Dr. Yaakov Nahmias, Hebrew University of Jerusalem, Israel).

Ready Source of Functional Liver Cells Should Boost Drug Development Efforts

Liver function in newborns kicks in only after exposure to certain nutrient factors derived from gut bacteria, and this phenomenon has been used to differentiate pluripotent stem cells into fully functional liver cells.   More...
09 Aug 2015

British Diabetes Research Program Awarded Major Funding Boost

A British project to develop a long term insulin-producing implant for treatment of diabetes has received a major infusion of funding that will allow it to proceed with its five-year work plan.  More...
09 Aug 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.