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BioResearch

Image: An artist\'s impression of bioprinting in action, a rapidly emerging technique for the building of living 3D tissue constructs (Photo courtesy of the University of Bristol).

Three-Dimensional Printing of Living Tissues with Stem Cell Bioink

A recent paper described an advance in the use of three-dimensional printing that enables the use of the technique to print living tissues from a bioink that contains stem cells and nutrients. More...
05 Jul 2016

Drug Development Based on Genome Editing Technology Receives Funding Boost

An American biopharmaceutical company dedicated to translating CRISPR/Cas9 gene-editing technology into transformative medicines announced the successful conclusion of Series B fund raising activities. More...
05 Jul 2016

PCR Market Rises to USD3.5 Billion for 2015

The total PCR (polymerase chain reaction) technologies market was valued at about USD3.5 billion for 2015, up from USD3.2 billion in 2013, according to Kalorama Information (New York, NY, USA), a healthcare market research company. More...
04 Jul 2016
Image: Left and right: Various species of Triatomine bugs, which if infected can transmit T. cruzi. Center: T. cruzi trypomastigote in a thin blood smear stained with Giemsa (Photo courtesy of the CDC).

Oral Nanocapsule Treatment Cures Mice with Chronic Phase Chagas Disease

Oral treatment with nanocapsules containing the Brazilian plant extract lychnopholide was shown to eradicate Trypanosoma cruzi in both the acute and chronic phases of Chagas disease. More...
30 Jun 2016
Image: The figure depicts the X-ray crystal structure of the serine protease urokinase-type plasminogen activator (green) in complex with a Camelid antibody fragment (orange). The Camelid antibody fragment (nanobody) displays an unusual inhibitory mechanism by binding to the active site region (highlighted in blue) of the serine protease where it mimics the binding of substrate (Photo courtesy of Dr. Tobias-Kromann-Hansen, Aarhus University).

Nanobodies Facilitate Studies of Enzyme Substrate Interactions

The unusual crystal structure of a nanobody in complex with a serine protease enzyme was established by X-ray crystallography. More...
29 Jun 2016
Image: This ribbon diagram shows two views of the structure of the enzyme Tps2 as it removes a phosphate from a sugar molecule (yellow, orange, and red). The result of this process is trehalose, which forms a tough coating on pathogenic fungi, enabling them to make the transition from the ambient temperature of the environment to the much hotter temperature inside a human host (Photo courtesy of Yi Miao, Duke University).

Structure of Enzyme for Trehalose Synthesis May Promote Drug Development

A team of molecular microbiologists has established the molecular structure of an enzyme required for synthesis of trehalose, a sugar required by several different pathogenic fungi. More...
29 Jun 2016
Image: Super-resolution imaging was used to capture the rearrangement of T-cell receptors from nanometer-scale protein islands (left) to micrometer-scale microclusters (right) after T-cell activation in mouse lymph nodes (Photo courtesy of the Salk Institute for Biological Studies).

Advanced Techniques Enable Mapping of Immune T-cell Surface Membranes

Advanced high-resolution (super-resolution) microscopy was used to map the surface membranes of immune T-cells before, during, and following activation by antigen-presenting cells. More...
28 Jun 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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