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BioResearch

Image: The micrograph on the left is of melanoma cells growing in a mouse model. On the right, arrows point to immune cells infiltrating a tumor with LATS1/2 deleted (Photo courtesy of the University of California, San Diego).

New Mechanism Explains How Tumor Cells Escape Immune System Attack

Despite the commonly accepted role of the Hippo pathway kinase enzymes LATS1/2 (large tumor suppressor 1 and 2) as tumor suppressors, a recent study found evidence that they actually helped cancer cells to avoid being targeted by the body's immune system. More...
15 Dec 2016
Image: A micrograph of a seminoma, a common germ cell tumor. Tumor cells show a fried egg-like appearance (Photo courtesy of Wikimedia Commons).

Chromosomal Amplifications and Deletions Characterize Germ Line Tumors

Cancer researchers have identified several distinct genomic features underlying the origin of germ cell tumors and that are associated with the chemosensitivity of this type of cancer, as well as changes that occur during the rare progression to chemoresistance. More...
14 Dec 2016
Image: The nCounter system offers a simple, cost-effective way to simultaneously profile hundreds of mRNAs, microRNAs, or DNA targets (Photo courtesy of NanoString).

MicroRNA Regulation Critical for Development of Pediatric Brain Tumors

Cancer researchers have uncovered the critical role played by microRNA regulation in the development of childhood brain tumors. More...
14 Dec 2016
Image: A close-up of Kratom plant leaves (Photo courtesy of Wikimedia Commons).

Kratom Benefits Controversy Explored as Adverse Effects Continue

A recent review article addressed the ongoing controversy regarding the possible medical benefits of the chemically active compounds in the leaves of the kratom tree. More...
14 Dec 2016
Image: A photomicrograph of NETs following four hours of immunofluorescence staining (Photo courtesy of Madison Floyd, Rada Laboratory, University of Georgia).

Bacterial Motility Is Required to Trigger Neutrophil Immune Response

A team of molecular microbiologists has found that the flagellar motion, which propels Pseudomonas aeruginosa bacteria, was required to generate an immune response, especially the production of neutrophil extracellular traps (NETs). More...
13 Dec 2016
Image: A structural model of the protein encoded by the PTEN gene (Photo courtesy of Wikimedia Commons).

Anemia Proteins Function Cooperatively with PTEN Tumor Suppressor

A recently discovered link between the rare childhood genetic syndrome Fanconi anemia and the PTEN tumor suppressor gene could lead to the development of improved treatment options for cancer patients with certain types of PTEN mutations. More...
13 Dec 2016
Image: A flexible polymer patch, which improves the conduction of electrical impulses across damaged heart tissue in animals, can be attached to the heart without the need for stitches (Photo courtesy of the University of New South Wales).

Novel Biocompatible Patch Repairs Heart Damage in Rat Model

A team of Australian and British bioengineers has developed an electrically active biocompatible insert that can repair damage to electro-responsive tissues, such as the brain, heart, and nervous system without need of sutures. More...
13 Dec 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.