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BioResearch

Image: A scanning electron micrograph (SEM) of a human neutrophil ingesting MRSA (Photo courtesy of the U.S. National Institute of Allergy and Infectious Diseases).

Mutation Found Determines Nature of Host Response to MRSA Infection

A recent paper described the genetic factors that determine why some individuals develop chronic methicillin-resistant Staphylococcus aureus (MRSA) infections while others develop infections that resolve relatively quickly. More...
22 Sep 2019
Image: A micrograph of the superficial cerebral cortex showing neuron loss and reactive astrocytes in a person who has had a stroke (Photo courtesy of Wikimedia Commons).

Distinctive mRNA Signatures May Prove Diagnostic for Cancer-Related AIS

A recently published paper described a distinctive molecular signature present in blood mRNA expression profiles of patients with cancer-related acute ischemic stroke (AIS) that could potentially lead to earlier diagnosis of cancer in these patients. More...
22 Sep 2019
Image: The Parsortix system for collection of circulating tumor cells (Photo courtesy of ANGLE plc).

Automated Collection of CTCs Improves Prostate Cancer Diagnosis

A recent paper described the benefits of circulating tumor cell (CTC) analysis for improving the diagnosis of aggressive prostate cancer beyond currently used PSA (prostate specific antigen) measurement, biopsy and/or MRI imagery. More...
16 Sep 2019
Image: Circulating tumor cell-free DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized (Photo courtesy of Wikimedia Commons).

Liquid Biopsy More Effective for Analyzing Tumor Drug Resistance Mutations

Results published in a recent paper suggested that liquid biopsy – specifically analysis of cell-free tumor DNA (ctDNA) – may capture the genetic diversity of acquired drug resistance better than classical surgical biopsy of the tumor. More...
16 Sep 2019
Image: A micrograph of a urine cytology specimen showing a polyomavirus infected cell (Photo courtesy of Wikimedia Commons).

New Liquid Biopsy Assay Reveals Host-Pathogen Interactions

A sensitive new assay employs high-throughput DNA sequencing to identify a large range of viral and bacterial pathogens in clinical samples, distinguish them from host DNA, and determine the degree of host tissue injury due to interaction with the pathogens. More...
09 Sep 2019
Image: The transverse section of a chorionic villus (Photo courtesy of Wikimedia Commons).

Method Developed for Enriching Trophoblast Population in Samples

A recent paper described a technique to increase the proportion of placental trophoblast cells in cervical samples by 700%, which enables individual trophoblasts to be picked out for genetic testing. More...
02 Sep 2019
Image: A scanning electron microscope (SEM) photograph of Papillomavirus particles (Photo courtesy of the Institut Pasteur/Odile Croissant).

RNA-Based Test Developed for HPV Detection and Cancer Diagnosis

An RNA-based diagnostic test was developed that can detect human papillomaviruses (HPVs) with performances comparable to or better than an HPV DNA-based reference diagnostic kit. More...
19 Aug 2019
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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