Urine Test to Measure Specific Biomarkers of COVID-19 Patients’ Immune System Could Predict Disease Severity

By LabMedica International staff writers
Posted on 29 Apr 2021

Urine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who were not infected with the coronavirus, suggesting that a urine test to measure these biomarkers could predict disease severity.

In addition, levels of these inflammatory markers were higher in patients with comorbidities such as high blood pressure and diabetes, according to researchers from Wayne State University (Detroit, MI, USA). Researchers said they undertook this study in hopes of determining whether biomarkers of COVID-19 could predict which individuals will develop "overly exuberant immune responses," also called a cytokine storm. They chose to screen the urine of COVID-19 patients because of its non-invasive nature that doesn't require the use of needles or blood samples.

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Scientists said they hope the results of this study will translate to a regular screening process for COVID-19 patients to predict who is more likely to develop severe disease and to aid in a successful treatment strategy.

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Wayne State University