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Pathology

Image: PathFlow Viewer and Automated Workflow are now European regulatory cleared for use in primary diagnosis (Photo courtesy of Gestalt)

Digital Pathology Solution Provides Truly Interoperable Platform to Streamline Workflow

Gestalt Diagnostics, Inc. (Spokane, WA, USA) has received CE-IVD marks for two of the main components of PathFlow. Both the PathFlow viewer and the proprietary, automated workflows now have European regulatory clearance for broad use in clinical, education, and research laboratories. More...
11 Oct 2022
Image: Capitainer B card’s microfluidic qDBS technology provides exact sample volume to a pre-cut DBS disc (Photo courtesy of Capitainer)

Novel Microfluidic qDBS-Sampling Technology Could Find Broader Use in Clinical Diagnosis

A new collaboration aims to accelerate method development for the implementation of a novel microfluidic quantitative dried blood spot (qDBS) sampling-based technology for clinical diagnostics in the US and globally. More...
07 Oct 2022
Image: Neutrophil gelatinase-associated lipocalin (NGAL) Duo Set ELISA (Photo courtesy of R&D Systems)

Synovial Fluid NGAL Accurately Diagnoses Prosthetic Joint Infection

Prosthetic joint infection (PJI) is a serious complication that is difficult to diagnose after joint arthroplasty and seriously affects the physical and mental health of patients. Current studies suggest that PJI is a relatively limited infectious disease, and the synovial fluid (SF) biomarkers more directly reflect the nature and extent of inflammation. More...
04 Oct 2022
Image: Colored scanning electron micrograph (SEM) of a bladder cancer cell. Its several long cytoplasmic projections may enable it to be motile (Photo courtesy of Steve Gschmeissner)

CDH1 Overexpression Predicts Early-Stage Bladder Cancer

Bladder cancer (BC) is a serious public health problem, but effective biomarkers for BC diagnosis, particularly in the early stage, are still lacking. Identification of reliable biomarkers associated with early-stage BC is of great importance to early treatment and an improved outcome. More...
29 Sep 2022
Image: Histopathology of Patient with Crohn\'s disease showing evidence of an epithelioid nonnecrotizing granuloma (Photo courtesy of Catherine E. Hagen, MD and Luisa Ricaurte Archila, MD)

Longitudinal Laboratory Data Predicts Complication in Crohn’s Disease Patients

Stenosis, fistulization, and perforation of the bowel are severe outcomes which can occur in patients with Crohn’s disease. Accurate prediction of these events may enable clinicians to alter treatment strategies and avoid these outcomes. More...
27 Sep 2022
Image: The Dako Autostainer Link 48 ensures optimal staining results and offers a high slide and reagent capacity (Photo courtesy of Agilent)

PD-L1 Expression Associated With Poorer Survival in Anal Squamous Cell Carcinoma

Although anal squamous cell carcinoma (ASCC) is a rare malignancy, making up only 0.5% of all cancer cases in the USA, disconcertingly, the annual incidence continues to rise both globally and in the USA. More...
27 Sep 2022
Image: IL-1RA antibody levels measured as a biomarker in young males with myocarditis after SARS-CoV-2 vaccination (Photo courtesy of Patrice Wendling)

IL-1RA Antibodies in Myocarditis After SARS-CoV-2 Vaccination

Myocarditis associated with messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) predominantly affects male adolescents and young male adults (14 to <30 years of age) and typically occurs after receipt of the second vaccine dose. More...
26 Sep 2022
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.