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Pathology

Image: ABI Prism 7700 Sequence Detection System (Photo courtesy of Applied Biosystems).

Methods Evaluated for HER2 Status in Breast Cancer

The human epidermal growth factor receptor 2 gene is overexpressed or amplified in approximately 15% to 20% of all breast cancers leading to a poorer prognosis. More...
23 Sep 2013
Image: Breast carcinoma (FFPE) stained with HercepTest (Photo courtesy of Dako).

Digital Pathology Solution Now Customized for Breast Cancer Diagnostics

A tissue-staining analysis tool has been made accessible within a digital pathology system and has been customized for breast cancer biomarkers. More...
09 Sep 2013
Image: OncoMap screening for DNA (Photo courtesy of Dana-Farber Cancer Institute).

Oncogenic Mutations Found in Cervical Cancer

Marked differences have been found in the genomic environment of the two most common types of cervical cancer, suggesting that patients might benefit from therapies geared to each type's molecular characteristics. More...
05 Sep 2013

Levels of CSF Biomarkers Diagnostic for Early Phase Parkinson's Disease

Analysis of cerebral spinal fluid from patients with early Parkinson's disease led to the identification of a group of proteins whose concentrations correlated with the severity of the disease. More...
02 Sep 2013
Image: Microfluidic chip capturing cancer cells (Photo courtesy of Peking University).

Microfluidic Chip Captures Live Tumor Cells from Blood

A neoteric microfluidic chip has been developed that can quickly and efficiently segregate and capture live circulating tumor cells from a patient's blood. More...
28 Aug 2013
Image: RNA microarray analysis: heat maps of gene expression values show how experimental conditions influenced production (expression) of miRNA for a set of genes. Green indicates reduced expression. Cluster analysis has placed a group of down regulated genes in the upper left corner (Photo courtesy of Wikimedia Commons).

MicroRNA Profiling Shows Promise as Diagnostic and Prognostic Tool for Bladder Cancer

Profiling of 15 microRNAs from bladder tissue showed with 100% accuracy whether the cells were normal or malignant,  while the determination of only two miRNAs could predict how well the patient would be able to defend against bladder cancer. More...
28 Aug 2013
Image: Blood agar plate showing colonies of Fusobacterium nucleatum (Photo courtesy of US National Library of Medicine).

Oral Bacteria May Cause Colorectal Cancer

Gut microbes have been linked to colorectal cancer, but it still unclear whether and how they might cause tumors to form in the first place. More...
27 Aug 2013
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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