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Pathology

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Blood Test Identifies When Cancer Treatment Becomes Detrimental

Some treatments for prostate cancer, while initially effective at controlling the disease, not only stop working after a certain period of time but actually start driving tumor growth.  More...
29 Sep 2014

Noninvasive Prenatal Test Assesses Risk for Aneuploidies

A noninvasive prenatal test employs next-generation sequencing to assess risk for multiple fetal chromosomal aneuploidies from a single blood sample.  More...
28 Sep 2014
Image: Histopathology of cervical intraepithelial neoplasia (CIN3) showing severe dysplasia that spans more than 2/3 of the epithelium, and may involve the full thickness. This lesion may sometimes also be referred to as cervical carcinoma in situ (Photo courtesy of KGH/Wikipedia Commons).

Clinical Results Presented for Urine-Based High-Risk HPV Assay

Two pilot studies have demonstrated that a urine-based assay for the detection of high-risk human papillomavirus had high sensitivity for identifying women with high grade cervical intraepithelial neoplasia.  More...
24 Sep 2014
Image: The ACD RNAscope 2.0 Brown kit for in situ hybridization (Photo courtesy of Advanced Cell Diagnostics).

Blood Test for Receptor Predicts Prostate Cancer Treatment Response

Prostate cancer patients whose tumors contain a shortened receptor called androgen-receptor splice variant 7 messenger ribonucleic acid are less likely to respond to two widely used drugs for metastatic prostate cancer.   More...
21 Sep 2014
Image: The multiplex biomarker immunoassay platform (Photo courtesy of Aushon BioSystems).

Blood Test Offers Specific Treatment for Ovarian Cancer

A new blood test has been developed allowing doctors to predict which ovarian cancer patients will respond to particular types of treatment.  More...
21 Sep 2014

Large Genetic Study Identifies New Prostate Cancer Loci

Data obtained during a large genetic screening study have added 23 new genetic variants to the known loci linked to development of prostate cancer.  More...
21 Sep 2014
Image: The Agilent 2100 bioanalyzer system provides sizing, quantitation and quality control of DNA, RNA, proteins and cells on a single platform (Photo courtesy of Agilent Technologies).

New Gene Mutations Found for Wilms Tumor

The genetic causes of Wilms tumor, a type of kidney cancer found only in children, has been revealed by whole-exome sequencing identifying missense mutations in the microRNA-processing enzymes.  More...
18 Sep 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.