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Pathology

Image: The MiSeq Next Generation Sequencing System (Photo courtesy of Illumina).

Cheaper Gene Panels Are Useful Alternative to Whole-Genome Sequencing

About 10% of women with a personal or family history of breast or ovarian cancer have at least one genetic mutation that, if known, would prompt their doctors to recommend changes in their care. More...
30 Apr 2014

New Test Could Accurately Predict Prostate Cancer Recurrence

A test based on genetic signature and tumor oxygen levels, which boost the test’s accuracy, can predict whether a man is at high risk of prostate cancer recurrence. More...
24 Apr 2014

$Image: Immunostaining of human lung tissue, fixed with HOPE, from a patients suffering from legionnaire\'s disease. One legionella protein (red-brown), the bacteria-containing vacuoles and individual legionella inside the scavenger cells can be detected. The infection process can be observed immediately using proteomics (Photo courtesy of Braunschweig University of Technology).$

Novel Method Prepares Tissue Samples for Analyzing Proteins

A new way of preparing patient tissue for analyses might soon become the new standard, possibly replacing tissues fixed with formalin, before they are embedded in wax-like paraffin and cut into razor-thin slices. More...
23 Apr 2014

Blood Test Provides Rapid Method of Detecting Solid Cancers

Circulating tumor DNA is a promising biomarker for noninvasive assessment of cancer burden, but existing detection methods have insufficient sensitivity or patient coverage for broad clinical applicability. More...
22 Apr 2014

Methylated DNA Blood Test Monitors Breast Cancer Progress and Treatment Response

An advanced assay that measures DNA hypermethylatation in blood samples can diagnose advanced breast cancer, as well as monitor tumor burden and treatment response in women with metastatic breast tumors. More...
21 Apr 2014

Image: Histopathology of laryngeal squamous cell carcinoma (Photo courtesy of Masaryk University).

Novel Biomarker Identified for Two Different Cancers

A new biomarker linked to better outcomes for patients with head and neck cancers and non-small-cell lung cancer has been identified. More...
17 Apr 2014

Imaging and Blood Test Work Together to Optimize Evaluation of Ovarian Cancer Risk

A new US Food and Drug Administration-cleared blood test that measures the levels of five proteins and then uses a proprietary algorithm and software to calculate a single risk score has been the topic of recent research comparing the test to two imaging modalities. More...
15 Apr 2014

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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.