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Pathology

Image: Schematics of the basis of the NuQ assays: A nucleosome is a section of DNA that is wrapped around a core of proteins. DNA is compacted as protein complexes in a “beads on a string” structure (Photo courtesy of VolitionRx Limited).

Blood Test Detects Early Stage Treatable Pancreatic Cancers

A recent clinical study has demonstrated that a blood-based diagnostic platform is able to accurately detect 84% of early, surgically-treatable pancreatic cancers with a high 92% specificity.   More...
20 Jan 2015
Image: Gross pathology of idiopathic cardiomyopathy. Opened left ventricle of heart shows a thickened, dilated left ventricle with subendocardial fibrosis manifested as increased whiteness of endocardium at autopsy (Photo courtesy of Dr. Edwin P. Ewing, Jr.).

Heart Failure Patients’ Blood Glucose Levels Predict Mortality Risk

The prognostic implications of blood glucose on a wide range of outcomes including early mortality, hospitalizations, and incident diabetes diagnoses have not been fully elucidated in acute heart failure syndromes.  More...
18 Jan 2015

Data Reinforce HPV as First-Line Test in Cervical Cancer Screening

Newly published data from a 3-year trial support new, interim professional guidance from medical societies on use of human papillomavirus as a first-line test in cervical cancer screening for women from age 25.   More...
18 Jan 2015
Image: Biopsy slide of a classic tubular adenoma polyp that is precancerous (Photo courtesy of Dr. Scot M. Lewey).

Fecal Occult Blood Screening Increases High-Risk Polyp Detection

The introduction of biennial colorectal cancer screening in a region of France increased the rate of diagnosis of high risk precancerous adenomas, sometimes called polyps, by 89%.  More...
12 Jan 2015
Image: Melanin pigment (light refracting granular material - center of image) in a pigmented melanoma (Photo courtesy of Wikimedia Commons).

Melanoma Development Linked to Relationship Between Pigment Synthesis and Mitochondrial Function

Development of melanoma, a potentially fatal type of skin cancer, is linked to the direct relationship between pigment production (melanogenesis) and generation of reactive oxygen species by the mitochondria.  More...
11 Jan 2015
Image: Photomicrograph of ductal breast carcinoma in situ shows several ducts to be filled with carcinoma cells (Photo courtesy of Breastpath).

Breast Cancer Test Optimizes Treatment Recommendations

The first prospective outcomes data from a large Women's Healthcare Study Group for contemporary adjuvant breast cancer trials has identified patients who would be more likely to benefit from chemotherapy treatment.   More...
06 Jan 2015
Image: An immunochromatographic fecal occult blood test (iFOBT), the Asan Easy Test FOB (Photo courtesy of Asan Pharm Co Ltd.).

Quantitative ELISA Stool Test Screens for Colorectal Cancer

A novel screening immunochromatographic kit has been evaluated for usefulness in detecting colorectal cancer and colonic adenoma by comparing it with other tests.   More...
05 Jan 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.