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Pathology

Image: Schematic design of the microfluidic device that sorts for aggressive cancer cells (Photo courtesy of Reinhart-King laboratory).

Microfluidic Device Selects Cancer Cells Based on Chemotactic Phenotype

A new approach has been invented for screening for aggressive cancer cells, using a microfluidic device that isolates only the most aggressive, metastatic cell.   More...
24 Jun 2014

NMR-Based Index Helps Identify Normal-Weight Individuals at High Risk for Type 2 Diabetes

Data suggests that a new, nuclear magnetic resonance-based diabetes risk index would improve risk assessment and intervention for at-risk patients, potentially preventing or slowing their progression to type 2 diabetes.   More...
23 Jun 2014
Image: Sarcocysts of Sarcocystis spp. in muscle tissue, stained with hematoxylin and eosin (Photo courtesy of the William Beaumont Hospital).

Rare Parasite Causes Relapsing Febrile Myositis

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19 Jun 2014
Image: Histopathology micrograph of prostatic acinar adenocarcinoma, the most common form of prostate cancer (Photo courtesy of Nephron).

Prostate Cancer Biomarkers Identified in Seminal Fluid

Improved diagnosis and management of one of the most common cancers in men, prostate cancer, could result from discovery that seminal fluid contains biomarkers for the disease.  More...
18 Jun 2014
Image: Histopathology of mammary tissue, high grade breast cancer (Photo courtesy of Johns Hopkins Medicine).

Four New Genes Added to Inherited Breast Cancer Risk List

Based on risk and frequency, three classes of breast cancer susceptibility genes or loci are currently recognized, but four more genes have been added the growing list of higher risk genes.   More...
17 Jun 2014
Image: Micrograph of a pleural fluid cytopathology specimen showing mesothelioma (Photo courtesy of Wikimedia Commons).

Panel of siRNAs Acts as Biomarker for Diagnosis of Malignant Pleural Mesothelioma

A panel of four siRNAs has been cited as a potential biomarker that is able to differentiate malignant pleural mesothelioma from noncancerous pleural tissue with reactive mesothelial proliferations.  More...
17 Jun 2014
Image: Metastasis requires the presence of three cells in direct contact on a blood vessel wall: a tumor cell that produces the protein MENA; a perivascular macrophage (cells that guide tumor cells to blood vessels); and a blood-vessel endothelial cell. The presence of three such cells in contact with each other is called a tumor microenvironment of metastasis, or TMEM, which is depicted within the box in this illustration (Photo courtesy of Albert Einstein College of Medicine of Yeshiva University).

Novel Immunoassay Predicts Risk of Breast Cancer Metastasis

A novel diagnostic test that identifies sites where breast tumors are able to metastasize was used to predict risk of distant metastasis in ER+/HER2− breast cancer independently of IHC4 score and classical pathologic features.   More...
16 Jun 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.