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Pathology

Image: Immunohistochemical staining of ovarian tissue with anti-CA125 for the diagnosis of ovarian carcinoma; the neoplastic cells are strongly stained (Photo courtesy of Epitomics).

Test Model Discriminates Ovarian Tumors

A new test can discriminate between benign and malignant ovarian tumors, and identify different types of carcinomatous tumors, with a high level of accuracy.  More...
28 Oct 2014
Image: Immunofluorescence staining pattern of ANCA using FITC conjugate demonstrates presence of antineutrophil cytoplasmic antibodies (ANCA). Top left - PR3 antibodies on ethanol-fixed neutrophils showing a cytoplasmic ANCA pattern. Bottom left - PR3 antibodies on formalin-fixed neutrophils showing a cytoplasmic ANCA pattern. Top right - MPO antibodies on ethanol-fixed neutrophils showing a perinuclear ANCA pattern. Bottom right - MPO antibodies on formalin-fixed neutrophils showing a cytoplasmic ANCA pattern (Photo courtesy of Wikimedia Commons).

Monitoring ANCA Levels Helps Predict Relapse of Systemic Vasculitis in Patients with Kidney Involvement

Repeated measurement of levels of anti-neutrophil cytoplasmic antibodies predicts likelihood of relapse in patients suffering from systemic vasculitis with kidney involvement.  More...
28 Oct 2014
Image: Histopathology of prostatic acinar adenocarcinoma, the most common form of prostate cancer, Gleason pattern 4, from prostate curettings (Photo courtesy of Nephron).

Protein-Based Test Improves Prognostic Accuracy for Prostate Cancer

A protein-based biopsy test has been designed to improve the accuracy of prognosis for men diagnosed with prostate cancer and can help identify the aggressiveness of the disease.   More...
27 Oct 2014

Prostate Cancer Specific RNAs Identified in Urine and Tissue

Researchers have discovered a set of potential-biomarker RNAs that may pave the way to a more reliable prostate cancer screening assay.  More...
27 Oct 2014
Image: Tumor cell populations identified using digital image analysis from a stained pathology slide, with the tumor regions detected and now colored orange (Photo courtesy of Definiens).

Biomarker Reveals Cause of Papillary Thyroid Carcinoma

The expression of the CAP-GLY domain containing linker protein 2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin.  More...
26 Oct 2014
Image: The DEPArray System for analyzing individual cells (Photo courtesy of Silicon Biosystems).

Genetic Mutation Detected in Circulating Tumor Cells

Tissue biopsies from metastatic cancer patients are invasive procedures that are frequently impossible due to the lack of accessible lesions, but a sample is required for genetic analysis.   More...
26 Oct 2014
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Molecular Immunohistochemical Profiling Identifies Invasive Breast Carcinoma

Molecular and immunohistochemical profiling of invasive micropapillary carcinoma of the breast was used to identify potentially useful markers for targeted therapies with a focus on a specific gene mutation.   More...
23 Oct 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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