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Pathology

Image: Cancerous cells release small packages of exosomal ribonucleic acid (Photo courtesy of US National Institute of Health).

Liquid Biopsy Test Detects Non-Small-Cell Lung Cancer

Plasma-based assays overcome key challenges associated with tissue-based approaches, enabling sensitive, accurate, real-time mutation detection in non-small-cell lung cancer patients.  More...
23 Sep 2015
Image: Model of the p27KIP1 (cyclin-dependent kinase inhibitor 1B) protein (Photo courtesy of Wikimedia Commons).

Keratin 17 Oncoprotein Potential Cervical Cancer Biomarker

The keratin protein K17, which was thought to play a purely passive mechanical support role for tumors, has been shown to act as a cancer-promoting oncoprotein whose expression by cervical cancer cells is linked to decreased likelihood of survival.   More...
21 Sep 2015
Image: Histopathology of a testicular seminoma with classical histologic features including a prominent lymphoid stromal infiltrate and typical cytomorphology (Photo courtesy of Mattopaedia).

Testicular Cancer Risk Comes from Inherited Genetic Faults

Testing for a range of genetic variants linked to testicular cancer could be effective in picking out patients who are at substantially increased risk, and therefore, potentially opening up ways of preventing the disease.  More...
20 Sep 2015
Image: Histopathology of advanced gastric carcinoma of the intestinal type shows gland-forming adenocarcinoma and adjacent intestinal metaplasia (Photo courtesy of Drs. Shabnam Bashir and Sudip Raina).

Biomarker Helps Predict Stomach Cancer Survival

A biomarker has been identified in patients with stomach cancer that starves tumors of their blood supply and reduces the ability of cancer cells to spread to other parts of the body.   More...
16 Sep 2015
Image: Histopathology of hilar cholangiocarcinoma or Klatskin tumor (Photo courtesy of the Nephron).

Independent Prognostic Biomarker Found for Klatskin Tumor Patients

Curative treatment of intrahepatic cholangiocarcinoma and hilar cholangiocarcinoma is limited to surgical resection or orthotopic liver transplantation, however, not all patients benefit from a surgical approach and suffer from early tumor recurrence.  More...
16 Sep 2015
Image: A comparison of stained bright-field microscopy (top row) and SLIM (bottom row) images in their respective abilities to show malignant and benign. The images were obtained from adjacent sections. Color bars are in radians (Photo courtesy of Hassaan Majeed).

Breast Cancer Diagnosis Uses Spatial Light Interference Microscopy

The standard practice in histopathology of breast cancers is to examine a hematoxylin and eosin stained tissue biopsy under a microscope to diagnose whether a lesion is benign or malignant.  More...
16 Sep 2015
Image: Histopathology of a tubular adenoma (left of image), a type of colonic polyp and a precursor of colorectal cancer (Photo courtesy of Nephron).

Liquid Biopsy Diagnostic Test for Colorectal Cancer Launched

A new test has been launched that uses a patient's blood sample to detect Kirsten rat sarcoma viral oncogene homolog, a predictive biomarker for solid tumor cancers.  More...
14 Sep 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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