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Image: The instrument used for the In-DX panel for rapidly detecting bacteria (Photo courtesy of G.L. Kohuth, Michigan State University).

Faster Way of Detecting Bacteria Developed

A faster way to detect the pathogenic bacteria that may cause patients to become sick has now been developed, giving physicians a better chance at saving lives by proscribing the most suitable antibiotic. More...
16 Feb 2017
Image: A new technique for identifying tumor-derived extracellular vesicles (EVs) relies on differently shaped nanoparticle probes that refract light at different wavelengths, one spherical (green) and one rod-shaped (red). One probe identifies the surface protein ephA2 linked with pancreatic cancer; the other probe identifies a common EV surface protein. Only pancreatic cancer-derived EVs express both proteins and thus bind both nanoparticles to emit a brilliant yellow signal that allows these disease-linked EV’s to be easily detected for diagnostic purposes. This method can also be used to monitor effectiveness of anti-cancer treatment by measuring abundance of tumor-derived EV’s over the course of therapy (Photo courtesy of Arizona State University / Jason Drees).

Marker Detection Leads to Earlier Pancreatic Cancer Testing

With nanoplasmonic technology that enabled quantification of tumor-derived extracellular vesicles (EVs) in patient blood plasma microsamples, researchers have developed a noninvasive, inexpensive, rapid test for early diagnosis of pancreatic cancer (PC) as well as for monitoring of treatment-response and cancer burden in patients with PC. More...
15 Feb 2017
Image: Tin dioxide manocrystal sensors for volatile organic compounds (VOC) detection. (Top) – Schematic representation of the SnO2 nanorod sensor for VOC detection. (Bottom) – Sensor response in relation to pore size for 100 ppm ethanol gas changes by 5 orders of magnitude at 250 degrees Celsius (Photo courtesy of Professor Tetsuya Kida, Kumamoto University / ACS).

Novel Approach Enables Ultrasensitive Detection of Volatile Organic Compounds

By a pore tuning approach using anisotropically shaped sno2 nanocrystals, scientists have developed highly sensitive gas sensors for volatile organic compound (VOC) detection. More...
14 Feb 2017
Image: Dr. Perena Gouma displays a hand-held breath monitor that can detect the flu virus (Photo courtesy of the University of Texas, Arlington).

Breathalyzer Test for Personalized Disease Detection

A novel breathalyzer device has been developed that enables detection of volatile compounds produced by respiratory viruses such as the influenza virus and other pathogenic microorganisms. More...
14 Feb 2017
Image: Visual determination of positive and negative samples. Examples of malaria CZC-LAMP tubes after the reaction. It is not possible to determine positive or negative under natural light due to the interference by hemoglobin (lower). However, positive samples emit green fluorescence under 505 nm blue-green light (upper) (Photo courtesy of Hokkaido University School of Medicine).

Direct Blood Dry LAMP System Detects Malaria Species

Plasmodium falciparum is thought to be the most prevalent among Plasmodium species and although this species has been well investigated epidemiologically, non-P. falciparum malaria infections have been rather neglected because of their less severe clinical symptoms and difficulties of diagnosis. More...
09 Feb 2017
Image: A sample of 500 nanometer particles in solution. In the top image, the acoustic whirlpool device was turned off. The bottom image shows that when the device was turned on, the nanoparticles were concentrated to the point of becoming visible as a dark line down the center of the chamber (Photo courtesy of Duke University).

Immunoassay Device Based on Acoustic Vortex Nanoparticle Enrichment

An inexpensive acoustic transducer is the key to a novel immunoassay that may eventually be combined with a smartphone camera to form a platform for the rapid detection of diagnostic proteins in blood, urine, or saliva samples. More...
08 Feb 2017

Smartphone-Based Optical Imaging Offers Onsite Diagnostics

A novel smartphone-based optical imaging and molecular assay system permits on-site diagnostics and facilitates transfer of molecular diagnostic data from the point-of-care (POC) to the point-of-expertise, providing a cost-effective means for molecular diagnostics even in resource-limited settings. More...
08 Feb 2017
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