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Technology

Image: The MammaTyper in vitro diagnostic test kit for breast cancer subtyping (Photo courtesy of BioNTech Diagnostics).

PCR Better at Identifying Breast Tumor Subtypes than Immunohistochemistry

A recently published study suggested that a RT-qPCR (reverse transcription quantitative real-time polymerase chain reaction) assay was superior to classical immunohistochemistry for subtyping breast tumors. More...
27 Jun 2016
Image: A colorized scanning electron micrograph (SEM) showing a number of Gram-negative Escherichia coli bacteria of the strain O157:H7 (Photo courtesy of the CDC).

Nanoscale Biosensor for Detection of Pathogenic Bacteria under Field Conditions

A team of bioengineers used nanoscale technology to develop a simple, portable biosensor system for detection of pathogenic bacteria – such as the diarrhea-causing Escherichia coli (E. coli) 0157:H7 – under field conditions. More...
27 Jun 2016
Image: Assay principles: Unpurified PCR product is added to a micro well containing probe-conjugated microbeads. A wild-type target hybridizes efficiently to both probes, inducing bead aggregation. Hybridization of a mutant target to the discriminating probe is unfavorable; therefore, the beads remain dispersed. An image of each micro well is obtained and processed to generate a saturation value corresponding to the extent of aggregation (Photo courtesy of The Journal of Molecular Diagnostics).

Rapid Technique Described for Detection of KRAS Mutations in Pathology Specimens

A recent paper described a rapid and inexpensive method for detecting KRAS mutations in clinical biopsy specimens of lung and colorectal cancers. More...
20 Jun 2016
Image: Smartphone technology has been applied for evaluating the physical stress experienced by biological samples during transit in a hospital\'s pneumatic tube transport system (Photo courtesy of the University of Virginia Health System).

Smartphone-based Method Introduced for Evaluating Pneumatic Tube Systems

Investigators at the University of Virginia Health System (Charlottesville, USA) used accelerometer, chronometer, video, and illumination smartphone applications to evaluate the conditions during transport through the facility's pneumatic tube system following the discovery of some damaged blood sample tubes. More...
13 Jun 2016
Image: A biosensor detects molecules linked to neurodegenerative diseases and cancer (Photo courtesy of University of Campinas).

Electronic Device Detects Molecules Linked To Neurodegenerative Diseases

A biosensor has been developed and has proven capable of detecting molecules associated with neurodegenerative diseases and some types of cancer. The device is basically a single-layer organic nanometer-scale transistor on a glass slide. More...
09 Jun 2016
Image: A female Aedes aegypti mosquito, a vector of the Zika virus, obtaining a blood meal from a human host (Photo courtesy of James Gathany / CDC).

Urine Trumps Blood For Zika Testing

Limited data suggest Zika virus is excreted in multiple body fluids, including urine and saliva and that urine and saliva might be more appropriate specimens than blood samples for evaluating Zika virus disease. More...
08 Jun 2016
Image: The BX51 optical microscope (Photo courtesy of Olympus).

Egg Size Differentiates Causative Agents of Human Diphyllobothriosis

Tapeworms of the order Diphyllobothriidea are parasites of tetrapods and several species may infect man and cause neglected human disease called diphyllobothriosis, which occurs in areas where lakes and rivers coexist with human consumption of raw or undercooked freshwater fish. More...
07 Jun 2016
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