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Image: The Exodisc device effectively isolates extracellular vesicles from biological samples such as urine or blood (Photo courtesy of the Ulsan National Institute of Science and Technology).

Device Automates Collection of Extracellular Vesicles from Biological Fluids

A team of Korean cancer researchers has developed an automated system for isolating extracellular vesicles from biological fluids such as cell culture growth medium, urine, or blood. More...
15 Mar 2017
Image: The Zika virus is transmitted to humans through the bite of an infected Aedes mosquito, such as A. aegypti (Image courtesy of Florida Atlantic University).

Portable Device Being Developed to Detect Zika at POC

A handheld diagnostic device may enable detection of Zika virus accurately, rapidly, and inexpensively in many settings, even at airports as it requires only a saliva sample. More...
10 Mar 2017
Image: The lab-on-a-chip comprises a clear silicone microfluidic chamber for housing cells and a reusable electronic strip — a flexible sheet of polyester with commercially available conductive nanoparticle ink (Photo courtesy of Zahra Koochak, Stanford University).

Inexpensive Diagnostic Device May Revolutionize Medical Care

A radically designed “lab on a chip” diagnostic device is expected to dramatically reduce the cost of isolating and characterizing rare cells and molecules, a process that is of critical importance in diagnosis of common lethal diseases such as malaria, tuberculosis, HIV, and cancer. More...
28 Feb 2017
Image: The Fluid Assisted Separation Technology (FAST) Disc can accurately identify circulating tumor cells (CTCs) in the bloodstream (Photo courtesy of the Ulsan National Institute of Science and Technology).

Liquid Filtration System Captures Circulating Tumor Cells

A stand-alone lab-on-a-disc system captures from the blood 95% of circulating tumor cells (CTCs), which can be analyzed for early detection of cancer metastasis and for monitoring response to various cancer treatments. More...
21 Feb 2017
Image: The setup for the lens-free analysis of cerebrospinal fluid clinical specimen (Photo courtesy of Aix Marseille University).

Cerebrospinal Fluid Lens-Free Microscopy Used to Diagnose Meningitis

The performance of the cytological analysis of the cerebrospinal fluid (CFS) and enumerating leukocytes and erythrocytes is a routine first step in the laboratory diagnosis of meningitis. CSF cytology and cell counting is routinely performed by optical microscopy. More...
17 Feb 2017
Image: The instrument used for the In-DX panel for rapidly detecting bacteria (Photo courtesy of G.L. Kohuth, Michigan State University).

Faster Way of Detecting Bacteria Developed

A faster way to detect the pathogenic bacteria that may cause patients to become sick has now been developed, giving physicians a better chance at saving lives by proscribing the most suitable antibiotic. More...
16 Feb 2017
Image: A new technique for identifying tumor-derived extracellular vesicles (EVs) relies on differently shaped nanoparticle probes that refract light at different wavelengths, one spherical (green) and one rod-shaped (red). One probe identifies the surface protein ephA2 linked with pancreatic cancer; the other probe identifies a common EV surface protein. Only pancreatic cancer-derived EVs express both proteins and thus bind both nanoparticles to emit a brilliant yellow signal that allows these disease-linked EV’s to be easily detected for diagnostic purposes. This method can also be used to monitor effectiveness of anti-cancer treatment by measuring abundance of tumor-derived EV’s over the course of therapy (Photo courtesy of Arizona State University / Jason Drees).

Marker Detection Leads to Earlier Pancreatic Cancer Testing

With nanoplasmonic technology that enabled quantification of tumor-derived extracellular vesicles (EVs) in patient blood plasma microsamples, researchers have developed a noninvasive, inexpensive, rapid test for early diagnosis of pancreatic cancer (PC) as well as for monitoring of treatment-response and cancer burden in patients with PC. More...
15 Feb 2017
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