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Image: Microscopy images taken of Zika-infected primate placenta samples that were stained to detect Zika by immunohistochemistry. The left image shows a sample treated with the EASE protocol, with red/orange colored signals of Zika infection clearly visible (white arrows). The right image shows a sample treated with a standard protocol, and Zika virus - though present - was not detected (Photo courtesy of the University of Washington).

Horseradish Complex Increases Sensitivity of Immunochemical Assays

A new technique boosts the sensitivity of immunochemical reactions that rely on the enzyme horseradish peroxidase from 100 to 1,000 times. More...
01 Aug 2017
Image: The device employs two systems in miniature: a flow system and an optical system. The ratio of the two systems provides a quantitative indication about how the cancer is progressing (Photo courtesy of the Universitat Rovira i Virgili).

Optofluidic Device Quantifies CTCs in Blood

Researchers have developed a portable device that rapidly detects and counts circulating tumor cells (CTCs) in blood samples. It can help provide early diagnosis and help assess a patient’s level of health with convenient, inexpensive, effective testing for monitoring patients with cancer. More...
25 Jul 2017

Nanolock Sensor Detects Cancer Driver Mutation

Researchers have developed an accurate and sensitive “nanolock-nanopore” method that successfully diagnosed a known cancer driver mutation with results at the level of single DNA molecules in tumor tissues of thyroid cancer patients. The method can be adapted to detect a broad spectrum of both transversion and transition mutations, with applications from early diagnostics to individualized targeted therapy and monitoring. More...
24 Jul 2017
Image: A structural representation of the ApoE protein from human blood plasma (Photo courtesy of Wikimedia Commons).

Alzheimer's Disease Biomarker Assay Heading for IVD Status

A clinical diagnostic kit that measures the concentration of the Alzheimer's disease blood biomarker APOEepsilon4 was unveiled at the Alzheimer’s Association Conference held in London, United Kingdom, from July 16-20, 2017. More...
24 Jul 2017
Image: University of Illinois researchers and physicians at Carle Foundation Hospital developed a rapid test for sepsis that counts white blood cells and certain protein markers on their surface to monitor a patient\'s immune response (Photo courtesy of Janet Sinn-Hanlon).

Portable Device Finds Sepsis Infection Markers

A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood, which is the first to provide rapid, point-of-care measurement of the immune system's response, without any need to process the blood. More...
20 Jul 2017
Image: Research being conducted uses an atmospheric-pressure glow discharge plasma to probe samples for elemental and molecular species, and could lead to user-friendly MS analyses with broad capabilities (Photo courtesy of the Rensselaer Polytechnic Institute).

Mass Spectrometry Detection for the Masses

Researchers are developing a plasma-based technology to enable generalized use of mass spectrometry (MS) with new instruments that can analyze a much broader range of molecular species than current technology allows. More...
17 Jul 2017
Image: The dipstick device, a single-component, customizable, inexpensive biosensor uses live cells to detect pathogens worldwide (Photo courtesy of Columbia University).

Yeast-Based Tool Developed for Pathogen Detection

The monitoring of global pathogen burden has been traditionally limited to a small number of specialized centers, but more effective detection could be performed in real time by making accurate diagnostics accessible at the point of care. More...
13 Jul 2017
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.