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Image: A prototype of the D4 assay (Photo courtesy of Daniel Joh, Duke University).

Smartphone-Based ELISA Developed for Blood Antigens

A novel high speed, lab-on-a-chip ELISA test for antigens in blood samples depends on a unique nonstick polymer coating that eliminates the need for multiple incubation and washing steps. More...
14 Aug 2017

Dried Blood Assessment Equivalent to Drawn Blood Samples

A self-sampling method for therapeutic drug monitoring (TDM) of biologicals was developed that should enhance TDM implementation by patients with various autoimmune conditions. More...
14 Aug 2017
Image: The developed microfluidic chip enables sorting of cells at high speed of 16 microseconds. The enlarged view shows a demonstration of on-chip cell sorting of a Euglena gracilis cell (Photo courtesy of Nagoya University).

Pumps Achieve High-Speed Sorting of Large Cells

The sorting of individual cells is necessary for many medical applications, including the isolation of specific cell types from cell suspensions. A fluorescence-activated cell sorting (FACS) has been used for high-throughput cell sorting. More...
10 Aug 2017
Image: The CytoViva hyperspectral imaging system (Photo courtesy of CytoViva).

New Biomarkers Provide Diagnostic Tool for AD

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder that results in the gradual deterioration of specific brain regions that hinders the person’s ability to think, recall memories, learn, and perform daily tasks. More...
09 Aug 2017
Image: Sensing device: Simple characterizing target gas concentrations of human exhaled breath will lead to diagnose of the disease as well as physical condition (Photo courtesy of The Korea Advanced Institute of Science and Technology).

Innovative Nanosensor Developed for Disease Diagnosis

In human breath, diverse components are found including water vapor, hydrogen, acetone, toluene, ammonia, hydrogen sulfide, and carbon monoxide, which are more excessively exhaled from patients. Some of these components are closely related to diseases such as asthma, lung cancer, type 1 diabetes mellitus, and halitosis. More...
03 Aug 2017
Image: Microscopy images taken of Zika-infected primate placenta samples that were stained to detect Zika by immunohistochemistry. The left image shows a sample treated with the EASE protocol, with red/orange colored signals of Zika infection clearly visible (white arrows). The right image shows a sample treated with a standard protocol, and Zika virus - though present - was not detected (Photo courtesy of the University of Washington).

Horseradish Complex Increases Sensitivity of Immunochemical Assays

A new technique boosts the sensitivity of immunochemical reactions that rely on the enzyme horseradish peroxidase from 100 to 1,000 times. More...
01 Aug 2017
Image: The device employs two systems in miniature: a flow system and an optical system. The ratio of the two systems provides a quantitative indication about how the cancer is progressing (Photo courtesy of the Universitat Rovira i Virgili).

Optofluidic Device Quantifies CTCs in Blood

Researchers have developed a portable device that rapidly detects and counts circulating tumor cells (CTCs) in blood samples. It can help provide early diagnosis and help assess a patient’s level of health with convenient, inexpensive, effective testing for monitoring patients with cancer. More...
25 Jul 2017
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