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Image: (A and B) Photomicrographs of the layers of the device; (C) the mold ready for casting and (D) the chip mounted on a slide (Photo courtesy of San Diego State University).

Microfluidic Device Isolates Circulating Tumor Cell Clusters

The three main challenges of cancer treatment are metastases, recurrence, and acquired therapy resistance. These challenges have been closely linked to circulating cancer cell clusters. More...
03 Jul 2019
Image: The RAPIDPoint 500 Blood Gas System delivers fast, accurate and comprehensive test results for whole blood samples in approximately 60 seconds (Photo courtesy of Siemens Healthineers).

Ion-Selective Electrode Methods Compared for Electrolytes

Electrolytes are among the most commonly requested clinical laboratory tests. There are two methods for measuring electrolytes in plasma, both using the principle of an ion-selective electrode (ISE). More...
02 Jul 2019
Image: An illustration of a bacterial detection by the G-FET device (Photo courtesy of Osaka University).

Graphene-Based Transistor Detects Bacteria in Microdroplets

A team of Japanese researchers developed a graphene-based field-effect transistor and used it to detect the gastric cancer pathogen Helicobacter pylori in fluid microdroplets. More...
01 Jul 2019
Image: A peripheral blood film from a patient with sickle cell disease (Photo courtesy of Venngage).

New Method Rapidly Monitors Sickle Cell Disease

Sickle cell disease (SCD) is a hereditary disorder that affects red blood cells, distorting their natural disc shape into a crescent moon or "sickle" shape. Normal red blood cells move freely through small vessels throughout the body to deliver oxygen. With sickle cell disease, the misshapen red blood cells become hard and sticky, making it difficult for them to move through blood vessels. More...
26 Jun 2019
Image: Examples of migratory and non-migratory MDA-MB-231 breast cancer cells migrating in the MAqCI (Microfluidic Assay for quantification of Cell Invasion) device (Photo courtesy of Christopher L. Yankaskas, Johns Hopkins University).

Microfluidic Motility Device Indicates Likelihood of Breast Tumor Metastasis

A novel microfluidic motility test was shown to accurately predict a breast tumor's likelihood to generate metastases. More...
10 Jun 2019
Image: A diagram of the 3D-printed microchip electrophoresis device that can sensitively detect three serum biomarkers of preterm birth (Photo courtesy of Brigham Young University).

3D-Printed Device Detects Biomarkers of Preterm Birth

Preterm birth (PTB), defined as birth before the 37th week of gestation, is the leading complication of pregnancy and it affects about 1 in 10 pregnancies worldwide. Preterm infants can suffer complications such as neurological, respiratory and cardiac problems and, in some cases, even death. More...
06 Jun 2019
Image: The unique pipette tip created with a 3D printer to perform enzyme-linked immunosorbent assays (Photo courtesy of the University of Connecticut).

Novel 3D-Printed Technology Lowers Cost of ELISA

Traditional enzyme-linked immunosorbent assay (ELISA) tests are performed on plates featuring 96 micro-wells; each well works as a separate testing chamber where samples can be combined with various agents that will then react with the sample, typically by changing color. More...
06 Jun 2019
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