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Image: Beta-hemolytic colonies are distinguishable in agar co-cultures with alpha hemolytic S. pneumoniae. (A) Fluorescent and bright-field images of pure and admixed bacterial colonies in BHI agar with L-Hoechst (Photo courtesy of Temasek Life Sciences Laboratory).

Lipid Vesicles Replace Blood in New Bacteria Test

Beta-hemolytic bacteria are those pathogens that are frequently to blame for illnesses that are spread among school children like Streptococcus, or those like Listeria that cause many foodborne illnesses. The current test involves streaking a patient sample onto blood agar plates. More...
04 Oct 2017
Image: The novel automated slide-based approach: a microscope slide is moved under a blunt needle, providing a constant flow of whole blood. Typically, 1 μL of blood is deposited (Photo courtesy of James W. Winkelman, MD, et al).

Automated Slide-Based Approach Introduced for CBCs

The most commonly performed clinical laboratory test is the complete blood count (CBC). Currently, laboratory CBC systems obtain cell counts and morphologic information by maintaining the blood cells in a liquid “flow” and by using the Coulter impedance-based orifice or laser-based cytometry. More...
14 Sep 2017
Image: The fingerprint sample collection cartridge and the portable Reader 1000 analysis unit for drug screening (Photo courtesy of Intelligent Fingerprinting).

World’s First Portable Fingerprint Drug Test Launched

The world’s first portable fingerprint-based drug screening system has been launched and is available now. The revolutionary system is hygienic and easy-to-use, collecting fingerprint samples in just five seconds and delivering simultaneous screening results in less than ten minutes for the four main drug groups: cocaine, opiates, cannabis and amphetamines. More...
13 Sep 2017
Image: Paper-based diagnostic device that detects biomarkers and identifies diseases by performing electrochemical analyses. The assays change color to indicate specific test results. The device can be plugged into the handheld potentiostat, at left (Photo courtesy of Purdue University, Aniket Pal).

Disposable POC Device Introduced for Low-Resource Areas

A recent paper described a novel diagnostic device fabricated from various types of paper to be used for point-of-care testing in areas lacking electricity and other resources. More...
05 Sep 2017
Image: A representative picture of Giemsa-stained hydrophilic-treated COC plates; Arrows indicate Plasmodium-infected cells (Photo courtesy of National Institute of Advanced Industrial Science and Technology).

Malaria Diagnosis Employs Hydrophilic-Treated Plastic Plates

Malaria is a red blood cell (RBC) infection caused by Plasmodium parasite and to determine RBC infection rate, which is essential for malaria study and diagnosis, microscopic evaluation of Giemsa-stained thin blood smears on glass slides is performed. More...
30 Aug 2017
Image: Klebsiella pneumoniae growing in the microfluidic chip imaged in phase contrast. The bacteria are 3 µm long and divide every 30 minutes (Photo courtesy of Özden Baltekina et al).

New Ultrafast Method Determines Antibiotic Resistance

Antibiotic resistance is a growing medical problem that threatens human health globally. One important contributory factor in the development of resistance is the incorrect use of antibiotics for treatment. More...
24 Aug 2017
Image: The spectral transmission-reflectance-intensity (TRI)-Analyzer attaches to a smartphone and analyzes patient blood, urine, or saliva samples as reliably as clinic-based instruments that cost thousands of dollars (Photo courtesy of the Department of Bioengineering, University of Illinois at Urbana-Champaign).

Smartphone-Based Analyzer Designed for Sample Testing

A handheld spectrophotometer that uses a smartphone camera to measure changes in absorption of natural light or emission of fluorescent light is the key to a mobile instrument that can evaluate biological samples with the accuracy of clinical laboratory analyzers but at a fraction of the cost. More...
21 Aug 2017
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