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Technology

Image: The RainDrop digital PCR system (Photo courtesy of RainDance Technologies).

Factors Affecting Plasma DNA Analysis Evaluated

There is vast potential in precision-medicine methods of both detecting and monitoring disease by looking for indications of cancer mutations in cell-free DNA (cfDNA), circulating in the blood. However, there are many factors that can significantly alter these samples as they are collected and analyzed. More...
21 May 2018
Image: The Genedrive HCV ID kit is a qualitative assay providing results in 90 minutes in a decentralized environment (Photo courtesy of Genedrive).

Near-Patient Hepatitis C Assay Validated

Chronic infection with hepatitis C virus (HCV) is a major public health problem, estimated to infect 1.0% of the world’s population (71 million people) and to be responsible for 400, 000 annual deaths as a result of cirrhosis and liver cancer. More...
17 May 2018
Image: The C1000 Touch thermal cycler (Photo courtesy of Bio-Rad).

Assays Using ddPCR Quantify DNA Fragments

Optimized droplet digital polymerase chain reaction (ddPCR) assays have been developed that quantify short and long DNA fragments. These assays have been used to analyze plasma cell-free (cfDNA) fragment size distribution in human blood. More...
14 May 2018
Image: A microscopic appearance of cell blocks prepared by the HistoGel + ethanol (EtOH) method versus HistoGel-only and the EtOH-only methods. The insets in C and F illustrate excellent cytomorphologic preservation with this method (Photo courtesy of Memorial Sloan Kettering Cancer Center).

Cell Block Prep Method Modified for Molecular Studies

Biomarker testing is currently required to guide the selection of a growing number of targeted therapies in patients with a wide range of malignancies. Combined with increasing use of immunostaining for tumor diagnosis, this has substantially increased the demand for the amount of tissue in small specimens. More...
14 May 2018
Image: The low-cost, portable laboratory on a phone that can interpret results from a microplate assay (Photo courtesy of Washington State University).

Smart Phone Reader Detects Common Pathogens

In rural or low resource areas, doctors sometimes must rely on a patient's symptoms or use their own judgement in looking at test sample color results to determine whether a patient has an infection. More...
10 May 2018
Image: A diagram of the microfluidic device that uses magnetic particles and wavy-herringbone design to capture and release circulating tumor cells (Photo courtesy of Lehigh University).

Cancer Blood Test Engineered to Detect Tumors Early

A new innovative microfluidic device has been developed that uses magnetic particles and wavy-herringbone design to capture and release circulating tumor cells (CTC) with a high capture efficiency rate at different tumor cell concentrations. More...
02 May 2018
Image: The DxH 520 is designed to help low-volume labs enhance patient care through increased productivity with reduced costs (Photo courtesy of Beckman Coulter Diagnostics).

Beckman Coulter Announces CE Mark for Hematology Analyzer

Beckman Coulter (Brea, CA, USA) announced achievement of CE Mark for its DxH 520 hematology analyzer, designed to help physician office laboratories deliver high-quality results with increased productivity and ease. With as little as two environmentally friendly reagents, the compact five-part differential system enhances efficiency and resource management through a comprehensive feature set that automates daily tasks. This reduces the amount of time spent on laboratory operations and frees time for patient care. More...
30 Apr 2018
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.
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