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Image: Micrograph showing a prostate cancer (conventional adenocarcinoma) with perineural invasion (Photo courtesy of Wikimedia Commons)

Home Urine Collection for More Accurate Prostate Cancer Detection

 A standardized sampling system enables men being tested for prostate cancer to collect a urine sample at home and mail it to a laboratory for analysis. More...
09 Dec 2019
Image: Methods of extracting features from label-free immune cell analysis. Multivariate label-free data, composed of both morphological and spectral parameters, are used to identify high-level features at the single-cell level such as cellular type, response to drugs, as well as response differences between specimens (Photo courtesy of Osaka University)

Non-Invasive Microscopy Detects Activation and Distinguishes Cell Types

 Measurement techniques that allow the global analysis of cellular responses while retaining single-cell sensitivity are increasingly needed in order to understand complex and dynamic biological processes. More...
04 Dec 2019
Image: A new type of microscope has been developed that uses a bowl studded with LED lights of various colors and lighting schemes produced by machine learning (Photo courtesy of Duke University)

Optimized Microscope Hardware Developed for Accurate Image Classification

 Despite the widespread automation enabled by new post-processing software, the physical layout of the standard microscope has still changed relatively little as it is, for the most part, still optimized for a human viewer to peer through and inspect what is placed beneath. More...
03 Dec 2019
Image: Researchers introduced the first electrochemical CRISPR-based biosensor to help improve disease diagnostics (Photo courtesy of Richard Bruch, University of Freiburg)

CRISPR-based Electrochemical Biosensor Detects Disease-related MicroRNAs

 A microfluidic chip containing a CRISPR/Cas-based electrochemical biosensor has been introduced as a device for the rapid and precise analysis of the microRNAs involved in various disease states. More...
03 Dec 2019
Image: Simulations showing cancerous multiple myeloma cells, also known as cCPCs, getting stuck between micropillars in the new filter device. Blue outline is the cCPC and fluid is flowing is from top to bottom (Photo courtesy of Lidan You, University of Toronto)

Liquid Biopsy Filter Facilitates Multiple Myeloma Diagnosis

 A newly developed filtering device that collects circulating cancer cells from blood liquid biopsy samples demonstrated strong potential for facilitating diagnosis of multiple myeloma. More...
02 Dec 2019
Image: Schematic diagram of how the deep learning algorithm classifies leukocytes in a blood smear in an automated and standardized way (Photo courtesy of Helmholtz Zentrum München / Dr. Carsten Marr)

Acute Myeloid Leukemia Diagnosed by Convolutional Neural Networks

 Every day, millions of single blood cells are evaluated for disease diagnostics in medical laboratories and clinics. Most of this repetitive task is still done manually by trained cytologists who inspect cells in stained blood smears and classify them into roughly 15 different categories. More...
27 Nov 2019
Image: The new ClinSpec Diagnostics’ test can diagnose brain cancer from a blood sample (Photo courtesy of University of Strathclyde).

Chemical Analysis of Blood Samples Diagnoses Brain Tumors

 Brain tumors tend to have ambiguous symptoms, such as headache or memory problems, and a brain scan is currently the only reliable way of diagnosing them. In recent years, the use of infrared (IR) spectroscopy to analyze disease state in biofluids has been largely employed with promising results. More...
21 Nov 2019
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