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Image: This side-by-side comparison of a breast tissue biopsy demonstrates some of the infrared-optical hybrid microscope’s capabilities. On the left, a tissue sample dyed by traditional methods. Center, a computed stain created from infrared-optical hybrid imaging. Right, tissue types identified with infrared data. The pink in this image signifies malignant cancer (Photo courtesy of Rohit Bhargava, PhD).

All-Digital Histopathology Attained by Infrared-Optical Hybrid Microscopy

 The gold standard of tissue pathology is to add dyes or stains so that pathologists can see the shapes and patterns of the cells under a microscope. However, it can be difficult to distinguish cancer from healthy tissue or to pinpoint the boundaries of a tumor, and in many cases diagnosis is subjective. More...
24 Feb 2020
Image: The photo shows a portable lab that plugs into a smartphone to diagnose diseases like malaria or coronavirus (Photo courtesy of Joseph Fuqua II, University of Cincinnati Creative Services)

Autonomous Microchannel Analyzer Combines with Smartphone for Off-site Disease Diagnostics

 A novel microchannel capillary flow assay platform for detection of pathogenic microorganisms or other antigens combines with a smartphone for display, data transfer, storage, and analysis. More...
18 Feb 2020
Image: Detection and quantification of procalcitonin and C‐reactive protein using detection of inflammatory biomarkers imager (DENIS) (Photo courtesy of Ecole Polytechnique Fédérale de Lausanne).

Optical Biosensor Reduces Time for Sepsis Diagnosis

 New point‐of‐care diagnostic devices are urgently needed for rapid and accurate diagnosis, particularly in the management of life‐threatening infections and sepsis, where immediate treatment is key. More...
12 Feb 2020
Image: The flexible NextSeq 550 System offers a seamless transition between high-throughput sequencing and array scanning (Photo courtesy of Illumina).

Novel Enrichment Technology Indicates High Performance for Multi-Cancer Detection

 Breast, lung, pancreatic, and prostate cancer make up 41% of the cancer incidence in the USA. Early detection and a deep understanding of each cancer remain critical for implementing the highest quality of care. More...
10 Feb 2020
Image: Photomicrograph of cancer cells (Photo courtesy of Baylor College of Medicine)

A Needle Biopsy-based Proteogenomics Approach for Cancer Diagnosis

 A recent report described a proteogenomics approach for cancer diagnosis, which used tissue-sparing needle biopsy specimen processing and micro-scaled analytical proteomics techniques. More...
04 Feb 2020
Image: The system for rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR (Photo courtesy of Velox Biosystems).

Rapid UTI, Sepsis Tests Uses Digital PCR

 Sepsis due to antimicrobial resistant pathogens is a major health problem worldwide. The inability to rapidly detect and thus treat bacteria with appropriate agents in the early stages of infections leads to excess morbidity, mortality, and healthcare costs. More...
30 Jan 2020
Image: The Sebia Hydragel 18 Apo E Isofocusing showing different apoE isoforms from 16 patients tested. The “control serum” provided in the Sebia kit is included in each series, together with two already typed serum samples as internal controls (as an example, E3/E2 and E4/E4) (Photo courtesy of Sorbonne University).

Semi-Automatic Isoelectric Focusing Evaluated for Apolipoprotein E Phenotyping

 Plasma apolipoprotein E (apoE) mainly arises from liver hepatocytes (75%), but the brain (astrocytes, oligodendrocytes, microglia, astrocytes) also synthesizes apoE found in the cerebrospinal fluid. More...
30 Jan 2020
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.
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