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Microbiology

Image: Electron micrograph (x 68,490) of crystals of hemozoin isolated from the malaria parasite Plasmodium falciparum (Photo courtesy of Wikimedia Commons).

Novel Magnetic Resonance System Rapidly Determines Malaria Parasite Load

A novel diagnostic technique based on magnetic resonance relaxometry was able to rapidly and accurately determine severity of malaria infection without using chemical or immunolabeling.  More...
07 Sep 2014
Image: The parasite detection method is based on computer vision algorithms similar to those used in facial recognition systems combined with visualization of only the diagnostically most relevant areas. Tablet computers can be utilized in viewing the images (Photo courtesy of the Institute for Molecular Medicine).

Image Recognition Software Increases Accuracy of Malaria Diagnosis

A facial recognition software program has been adapted to assist in the identification of the malaria parasite by microscopic examination of blood smears.  More...
31 Aug 2014
Image: The ACCURUN 501 C. difficile Control set for use with human stool samples improves diagnostic assay performance monitoring and reliability of results (Photo courtesy of Gregg Shupe, SeraCare Life Sciences and PRNewsFoto).

New Control Helps Monitor C. difficile Assays with Higher Confidence

A ready-to-use Clostridium difficile control set for use with human stool samples improves diagnostic assay performance-monitoring and reliability of results.  More...
31 Aug 2014
Image: Blood smear showing a male gametocyte of Plasmodium vivax (Photo courtesy of Dr. Mae Melvin).

Three Detection Methods Compared for Malaria Gametocytes

Gametocytes are the transmission stages of malaria parasites and as their density in the human host is typically low, they are often undetected by conventional light microscopy.  More...
28 Aug 2014
Image: Leishmania amastigotes from a smear of a patient with cutaneous leishmaniasis (Photo courtesy of University of California, Los Angeles).

Cutaneous Leishmaniasis Diagnosed by Press Imprint Smear

The diagnostic method of choice for cutaneous leishmaniasis historically has been microscopic demonstration of the parasite and isolation of the protozoa in culture and detection of parasite DNA by molecular diagnostic methods.  More...
28 Aug 2014
Image: The Cryptococcal Antigen Lateral Flow Assay, the IMMY CrAg LFA (Photo courtesy of Immuno-Mycologics Inc).

Cryptococcal Disease Determined by Lateral Flow Assays

The detection of subclinical cryptococcal disease using antigen screening among human immunodeficiency virus-positive individuals presents a potential opportunity for prevention of both clinical disease and death.   More...
27 Aug 2014
Image: Scanning electron micrograph of a Trichomonas vaginalis trophozoite (Photo courtesy of Dr. Dennis Kunkel).

LAMP Assay Developed for Trichomoniasis

A loop-mediated isothermal amplification assay targeting a repeated DNA species-specific sequence was developed for detection of Trichomonas vaginalis, the causative agent of trichomoniasis.  More...
26 Aug 2014
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