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Microbiology

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Prognostic Biomarker Found for Post-Chemotherapeutic Relapse in Visceral Leishmaniasis

The effective clinical management, chemotherapy and control of the transmission of visceral leishmaniasis are largely dependent on early and unequivocal diagnosis as without effective chemotherapy symptomatic VL is usually fatal.  More...
05 Nov 2014
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Rapid Test Diagnoses Severe Sepsis

A rapid test has been developed that could help physicians predict within an hour if a patient will develop severe sepsis so they can begin treatment immediately.   More...
04 Nov 2014
Image: Leishmania detection sensitivity – Percentage of positivity in the different hsp70-PCRs (G, F, N, C), evaluated in the total of 98 clinical pre-confirmed cutaneous or visceral leishmaniasis case samples (All) and in different subsets (Bone marrow, Blood/BC[buffy coat], Lymph node, Skin biopsy) (Phot courtesy of Montalvo et al., September 2014, and the journal Diagnostic Microbiology and Infectious Disease).

New PCR Variants Evaluated for Global Diagnostics of Leishmaniasis

A study of three new PCR variants based on the leishmanial hsp70 gene, evaluated directly on clinical samples, has demonstrated the new tools to be globally applicable for Leishmania species-level typing in various geographical, clinical, and sampling contexts.    More...
04 Nov 2014
Image: Conidiophores of Aspergillus fumigatus (Photo courtesy of the CDC - [US] Centers for Disease Control and Prevention).

Analysis of Volatile Substances in Breath of Pneumonia Patients Confirms Fungal Infection Diagnosis

Analysis of volatile substances in the breath of patients with respiratory infections has been proposed as a novel, noninvasive, pathogen-specific approach to identifying the precise microbial cause of pneumonia.  More...
03 Nov 2014
Image: Transmission electron micrograph (TEM) reveals some of the ultrastructural morphology exhibited by a grouping of Enterovirus virions (Photo courtesy of the Centers for Disease Control and Prevention).

Rapid Molecular Test Developed for Enterovirus D68

A faster laboratory test has been developed to detect Enterovirus D68 in specimens from people with respiratory illness.   More...
02 Nov 2014
Image: An enzyme-linked immunosorbent assay (ELISA) kit for dengue virus NS1 antigen (Photo courtesy of Diagnostic Automation Inc.).

Diagnostic Test Kits for Dengue Virus Detection Evaluated

Laboratory diagnosis of dengue with a single serum specimen obtained during the acute phase of the illness requires tests to detect immunoglobulin M antibodies to Dengue virus or the virus genome.  More...
28 Oct 2014
Image: Prototype of the SP-IRIS (single particle - interferometric reflectance imaging sensor), which detects pathogens by shining light from multicolor LED sources on viral nanoparticles trapped onto the sensor surface by a coating of virus-specific antibodies (Photo courtesy of NexGen Arrays).

Device Developed for Rapid On-Site Pathogen Diagnostics

A novel nanotechnology-based prototype device can detect pathogens such as Ebola and other hemorrhagic fever viruses – quickly and on-site.  More...
26 Oct 2014
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.