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Immunology

Image: The Human P-Selectin ELISA Kit – serum vimentin levels were positively correlated with P-selectin in pediatric severe sepsis (Photo courtesy of MULTI SCIENCES(LIANKE) BIOTECH, CO.,LTD).

Serum Vimentin Predicts Mortality in Pediatric Severe Sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is a leading cause of death worldwide in the pediatric population. Vascular hyperpermeability by loss of endothelial barrier integrity is a hallmark of sepsis. More...
14 Jun 2022
Image: With the autoMACS Pro Separator, cells from whole blood or bone marrow can be isolated with minimal hands-on time (Photo courtesy of Miltenyi Biotec)

MRD in AML Detected by Deep Sequencing CD34+ Cells

Monitoring of measurable residual disease (MRD) in patients with acute myeloid leukemia (AML) is predictive of disease recurrence and may identify patients who benefit from treatment intensification. More...
09 Jun 2022
Image: Presepsin has been proposed as a `robust` biomarker of early-onset sepsis (Photo courtesy of Ian Ingram, BA)

Presepsin Proposed as 'Robust' Biomarker of Early-Onset Sepsis

Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm infants. Timely diagnosis can be challenging owing to unspecific presentation and questionable performance of the common markers of infection. More...
08 Jun 2022
Image: Immunolocalization of BmR1 homologues showing immunohistochemical results from worm sections that were processed (Photo courtesy of Washington University School of Medicine)

Novel Microfilarial Antigen Diagnoses Lymphatic Filariasis Infections

Lymphatic filariasis is a neglected tropical disease caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis (LF) is a deforming and disabling disease caused by parasitic nematodes that are transmitted by mosquitoes. More...
08 Jun 2022
Image: The Atellica NEPH 630 System is a low- to mid-volume nephelometric protein testing solution that simplifies laboratory operations by unifying instrument, assay, and IT connectivity (Photo courtesy of Siemens Healthineers)

Viral Antigen Detected in Cerebrospinal Fluid of COVID Patients

Neurologic symptoms are common in patients hospitalized with COVID-19 and include anosmia, encephalopathy, encephalitis, and cerebrovascular manifestations, including stroke. The neuroinvasive capacity of SARS-CoV-2 is questionable. More...
31 May 2022
Image: Stem cell transplants are standard of care for cancers such as leukemia, and lymphoma. MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome (Photo courtesy of Cancer Treatment Centers of America)

Allogeneic Stem Cell Transplants Improve Microbiome, Immune Cells

Past studies have suggested ties between microbial diversity and favorable allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes, or transplants involving stem cells from healthy donors. The interactions between the gut microbial community and the immune system can influence an individual's response to a bone marrow transplant to treat leukemia, lymphoma, multiple myeloma, and other blood conditions. More...
30 May 2022
Image: UniCel DxI 800 Access Immunoassay System (Photo courtesy of Beckman Coulter)

Autoantibodies Combined With Tumor Markers Detect Lung Cancer

Lung cancer (LC) is one of the most common cancers in the world and is the primary cause of cancer-related death. According to the pathological type, LC can be categorized into small cell LC (SCLC) and non-small cell LC (NSCLC). NSCLC includes squamous cell carcinoma (LSC), adenocarcinoma (LAC), and large cell cancer. More...
26 May 2022
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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