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Immunology

Image: Immunofluorescence staining pattern of ANCA using FITC conjugate demonstrates presence of antineutrophil cytoplasmic antibodies (ANCA). Top left - PR3 antibodies on ethanol-fixed neutrophils showing a cytoplasmic ANCA pattern. Bottom left - PR3 antibodies on formalin-fixed neutrophils showing a cytoplasmic ANCA pattern. Top right - MPO antibodies on ethanol-fixed neutrophils showing a perinuclear ANCA pattern. Bottom right - MPO antibodies on formalin-fixed neutrophils showing a cytoplasmic ANCA pattern (Photo courtesy of Wikimedia Commons).

Monitoring ANCA Levels Helps Predict Relapse of Systemic Vasculitis in Patients with Kidney Involvement

Repeated measurement of levels of anti-neutrophil cytoplasmic antibodies predicts likelihood of relapse in patients suffering from systemic vasculitis with kidney involvement.  More...
28 Oct 2014
Image: An enzyme-linked immunosorbent assay (ELISA) kit for dengue virus NS1 antigen (Photo courtesy of Diagnostic Automation Inc.).

Diagnostic Test Kits for Dengue Virus Detection Evaluated

Laboratory diagnosis of dengue with a single serum specimen obtained during the acute phase of the illness requires tests to detect immunoglobulin M antibodies to Dengue virus or the virus genome.  More...
28 Oct 2014
Image: The API 5000 triple quadruple mass spectrometer (Photo courtesy of AB SCIEX).

Serum Prostate-Specific Antigen Measured by Tandem Mass Spectrometry

Prostate-specific antigen is a widely used blood test for detection and monitoring of prostate disease and many clinicians assume that all test methods produce essentially the same results, though differences do exist.   More...
23 Oct 2014
Image: The prototype polydimethylsiloxane (PDMS) chip containing a cascading microchannel network for multi-stage exosome analysis (Photo courtesy of the University of Kansas).

Circulating Exosomes Analysis Uses Microfluidic Technology

A new microfluidic approach has been developed to streamline and expedite the exosome analysis pipeline by integrating specific immunoisolation and targeted protein analysis of circulating exosomes.  More...
23 Oct 2014
Image: View across the 2-fold icosahedral axis of the Coxsackievirus B3 (Photo courtesy of Jean-Yves Sgro).

Prenatal Viral Exposure May Cause Type 1 Diabetes

Women who contract a viral infection during pregnancy transmit viruses to their genetically susceptible fetuses, sparking the development of type 1 diabetes.   More...
22 Oct 2014
Image: A fluorescent proximity ligation assay of protein-protein interactions (Photo courtesy of Abnova).

Blood Test Determines Esophageal Cancer Patient Treatment Options

A blood test that may be beneficial in indicating neoadjuvant treatment regimens for patients with esophageal squamous cell carcinoma has been introduced.   More...
21 Oct 2014
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New Fertility Test Assesses Ovarian Reserve for Pregnancy

A new anti-Müllerian Hormone fertility test increases the accuracy of ovarian reserve assessment compared to conventional methods as AMH is an important fertility marker used by healthcare professionals to assess ovarian reserve levels.  More...
16 Oct 2014
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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