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Immunology

Image: CAL2 stained megakaryocytes with CALR mutations in essential thrombocythemia (ET), primary myelofibrosis (PMF). The CAL2 immunostaining correlated 100% with the Sanger sequencing (Photo courtesy of DIANOVA).

New Antibody Improves Diagnosis of Myeloproliferative Neoplasms

When hematopoietic myeloid cells change malignantly in the bone marrow, this can lead to an uncontrolled proliferation of certain blood cells and humans then suffer from diseases that are referred to by the collective term myeloproliferative neoplasms.  More...
14 Oct 2015
Image: Transmission electron micrograph depicts a number of round Dengue virus particles (expanded image) that were revealed in a tissue specimen (Photo courtesy of Frederick Murphy).

Dengue Diagnosis Tested in Urine and Saliva Specimens

Dengue is the most important arthropod-borne disease affecting humans, representing a huge public health burden in affected countries. Symptoms are often nonspecific, hence the need for an early, sensitive, and specific diagnosis of dengue for appropriate management.   More...
13 Oct 2015
Image: Photomicrograph of the small intestine mucosa of a patient with active celiac disease (Photo courtesy of Ann-Christin Røberg Beitnes).

Simplified Blood Test Diagnoses Celiac Disease

The diagnosis of celiac disease requires a tissue sample from the small intestine, which can be extremely unpleasant, but a blood test has been developed which provides a rapid, painless answer.    More...
06 Oct 2015
Image: The CELLSEARCH semi-automatic system that can capture and quantify circulating tumor cells (Photo courtesy of Janssen Diagnostics).

Arterial Blood Liquid Biopsy Detects Circulating Melanoma Cells

Venous blood collection is simple and minimally invasive, and this approach has made circulating tumor cells testing readily available to many cancer patients. The major drawback is the fact that CTCs are not always detectable for patients with clinically evident metastatic disease.   More...
06 Oct 2015
Image: Nucleosomics Technology: The DNA in every cell is wound around protein complexes in a beads-on-a-string structure. Each bead is called a nucleosome. When cells die, the body breaks the DNA string up into individual nucleosomes which are released into the blood (Photo courtesy of VolitionRx Limited).

NuQ Blood Assay CE-Marked for Colorectal Cancer Detection

A blood-based diagnostic assay for detection of colorectal cancer has received Conformité Européenne marking, which enables European Clinical Use/Sale in 33 Countries with nearly 600 million people.  More...
04 Oct 2015
Image: A new catalyst that improved the sensitivity of the standard PSA ELISA test by about 110-fold was made of palladium nanocubes coated with iridium (Photo courtesy of Dr. Xiaohu Xia, Michigan Technological University).

Peroxidase Mimic Outperforms Natural Horseradish Peroxidase in ELISA Test

A test-of-concept study demonstrated that a synthetic catalyst that mimics the action of horseradish peroxidase could increase the sensitivity of a colorimetric enzyme-linked immunosorbent assay for human prostate surface antigen by more than 110-fold.  More...
29 Sep 2015
Image: For five (1-5) diagnostic antibodies: specific-binding curves of Total IgY in a complex protein solution binding to immobilized antigen. Data provide direct information about the specificity of three different production batches, highly valuable information especially for development of diagnostic assays. Curves for all antigen spots are shown. Binding of IgY is observed only to its respective immobilized antigen. (Photo courtesy of Sanovo Biotech).

Avian Antibodies with an Edge of Quality

New chicken IgY antibodies with SPRi validation of specificity and affinity provide an advantage in choosing antibodies for research and for development of diagnostic tests.  More...
24 Sep 2015
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Quality Control Material
iPLEX Pro Exome QC Panel
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Hepy Urease Test
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UN-9000
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Allerquant 14G B ELISA


The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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