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Immunology

Image: Long-lived plasma cells have a distinctive \"fried egg\" appearance, containing bubble-like vacuoles or lipid droplets, which are generally rare in bone marrow cell samples (Photo courtesy of Emory University).

Long-Lived Antibody-Producing Cells Identified in Bone Marrow

A distinct set of long-lived antibody-producing cells have been identified in the human bone marrow that function as an immune archive.  More...
03 Aug 2015
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Genetic Mutation Impairs Immunity in Candidiasis and Mycobacteriosis

Human inborn errors of immunity mediated by the cytokines interleukin-17A/F underlie mucocutaneous candidiasis, whereas inborn errors of interferon-γ immunity underlie mycobacterial disease.  More...
02 Aug 2015

New Biomarkers May Serve as Companion Diagnostics for Patients Being Treated with IL-2

A transcriptional-profiling study has identified biomarkers related to efficacy of interleukin-2 treatment and has identified patient age as a key determining factor of clinical efficacy.   More...
02 Aug 2015
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Automated Test for Galectin-3 Cleared for Chronic Heart Failure Prognosis

Higher levels of galectin-3 are associated with a more aggressive form of heart failure, which may make identification of high-risk patients using galectin-3 testing an important part of patient care.  More...
21 Jul 2015
Image: Joint inflammation from rheumatoid arthritis is typically symmetrical, occurring on both sides of the body at the same time (Photo courtesy of Dr. Melinda Ratini).

Immunoassays Could Predict Drug Failure in Arthritis Patients

Biologic drugs have dramatically improved the long-term health of people with severe rheumatoid arthritis reducing symptoms as well as joint damage and disability, but in about one in five patients the treatment stops working after a few months limiting their effectiveness.  More...
20 Jul 2015
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Longitudinal Cerebrospinal Fluid Biomarker Changes Predict Dementia

Changes in key biomarkers of Alzheimer's disease during midlife as seen in brain scans and cerebrospinal fluid of healthy adults may help identify those who will develop dementia years later.  More...
20 Jul 2015
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Measurement of Calcium-Binding Protein Diagnoses Intracranial Hemorrhage

Cranial computed tomography scans and hospital admission are increasingly performed to rule out intracranial hemorrhage in patients after minor head injury, particularly in older patients and in those receiving antiplatelet therapy.  More...
19 Jul 2015
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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