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Immunology

Image: The BD FACSAria III fluorescent cell sorter (Photo courtesy of BD).

Lung Eosinophils Play Protective and Beneficial Role

During allergic reactions such as asthma, the immune system does not work correctly and responds in an abnormal way to harmless allergens present in the environment such as pollen and dust mites. More...
08 Sep 2016
Image: The Sgx Clarity System, being developed for highly sensitive next-generation immunodiagnostic detection, provides simple and intuitive operation (Photo courtesy of Singulex).

Certification Enables Development of New Technology in Next-Gen Immunodiagnostics

ISO (International Organization for Standardization) 13485:2012 Certification has been granted by NSAI to help ensure high standard development of a proprietary Single Molecule Counting (SMC) technology for clinical use as a next-generation immunodiagnostic platform. More...
06 Sep 2016
Image: A malignant melanoma on a patient’s skin (Photo courtesy of the National Cancer Institute).

Immune Analysis of Biopsies Predicts Response to Melanoma Immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs. More...
01 Sep 2016
Image: Immune molecule IL-1β (the \"hot spots\" shown) senses bacterial infections (Photo courtesy of the UC San Diego Health).

Innate Immune Sensor of Microbial Proteolysis Revealed

The human immune system can quickly recognize and respond to bacterial infections, but sometimes this reaction can become skewed, leading to autoimmune diseases such as rheumatoid arthritis. In this case, a person's own immune system attacks "self" proteins instead of just foreign invaders. More...
01 Sep 2016
Image: A histopathology of active toxoplasmosis of the myocardium. Numerous tachyzoites of Toxoplasma gondii are visible within a pseudocyst in a myocyte (Photo courtesy of Dr. Edwin P. Ewing, Jr.).

Latent Toxoplasmosis Prevalence Analyzed Retrospectively

Primary maternal infection with Toxoplasma gondii during pregnancy can lead to prenatal infection of the unborn child, and vertical diaplacental transmission of Toxoplasma can seriously damage the embryo. Some prenatally infected children, asymptomatic at birth, can develop retinochorioiditis and other sequelae months or years later. More...
01 Sep 2016
Image: A histopathology of brain tissue showing acute venous thromboembolism of unknown etiology (Photo courtesy of Peter Anderson).

Simplified Assay Quantifies Circulating Activated Protein C

The protein C (PC) anticoagulant pathway plays a crucial role in the regulation of fibrin formation by inactivating the pro-coagulant cofactors factor Va and factor VIIIa. More...
24 Aug 2016
Image: The Lateral Flow Assay (LFA): results of the LFA run with positive (left) and negative (right) control sera (Photo courtesy of IHRC).

Lateral Flow-Based Antibody Test Developed for Trachoma

Trachoma, resulting from repeated infection with the bacterium Chlamydia trachomatis, is the leading global infectious cause of blindness and blinding trachoma as a public health problem is targeted for elimination by 2020. More...
24 Aug 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.