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Immunology

Image: The ARCHITECT i1000SR immunoassay analyzer (Photo courtesy of Abbott).

New Automated Periostin Immunoassay Developed

Periostin is being investigated as a potential biomarker for T-helper-2 (Th2)-driven asthma or eosinophilic inflammation and may help to identify patients more likely to benefit from interleukin-13-targeted treatments. More...
11 Jan 2017
Image: An MRI analysis – Lack of SatM resulted in resistance to fibrosis in mice (Image courtesy of laboratory of Prof. Akira, IFReC, Osaka University).

Abnormal Immune Cells Involved in Causing Fibrosis

Using a mouse model, researchers have discovered a form of atypical monocyte as well as a committed progenitor that are involved in development of fibrosis. More...
10 Jan 2017
Image: The Biomark microfluidic system for polymerase chain reactions (Photo courtesy of Fluidigm).

DNA Levels in Blood Correlated with Ovarian Cancer Outcomes

The development of blood biomarkers that can be used for early detection of cancer or to measure tumor burden and response to treatment is a major goal of translational cancer studies across all cancer types. More...
04 Jan 2017
Image: A colony of Aggregatibacter actinomycetemcomitans, showing the characteristic flower-like morphology (Photo courtesy of UCL Eastman Dental Institute).

Common Bacteria of Gum Disease Linked to Rheumatoid Arthritis

A bacterium known to cause chronic inflammatory periodontal infections may also triggers the inflammatory “autoimmune” response characteristic of chronic, joint-destroying rheumatoid arthritis (RA). More...
28 Dec 2016
Image: The BN ProSpec system and nephelometer (Photo courtesy of Siemens Healthcare).

Inflammatory Markers Predict Risk of Morbidity and Mortality

Inflammatory markers are known to be associated with cancer, chronic heart disease and other serious health conditions; however, the marker that is most useful in predicting these diseases continues to be debated. More...
22 Dec 2016
Image: The nCounter Analysis System is a novel digital read-out technology that provides direct multiplexed measurement of gene expression with high levels of precision and sensitivity (Photo courtesy of NanoString Technologies).

Stem Cell-Based Test Predicts Leukemia Patients' Response to Therapy

A 17-gene signature derived from leukemia stem cells has been developed that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment. More...
22 Dec 2016
Image: The cobas e 411 fully automated, random access system for immunoassay analysis (Photo courtesy of Roche Diagnostics).

Performance of Second Generation Cortisol Assay Evaluated

Untreated disorders of the adrenocortical system, such as Cushing’s or Addison’s disease, can be fatal, and accurate quantification of a patient’s cortisol levels is vital for diagnosis. A straightforward diagnostic approach is of essential importance, and accurate quantification of cortisol levels plays a key role in the diagnosis of patients with suspected disease. More...
21 Dec 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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