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Immunology

Image: Immunohistochemistry (IHC) staining of human epidermal growth factor receptor 2 (HER2) in biopsy specimens showing intratumoral homogeneity and heterogeneity (Photo courtesy of Fudan University).

Heterogeneity Influences Cancer Immunohistochemistry Results

Many gastric cancer (GC) patients are with inoperable lesions and endoscopic biopsy becomes the only available approach to obtain tumor tissues for human epidermal growth factor receptor 2 (HER2) assessment. Unlike resected specimens, biopsy specimens are influenced by many factors and in turn more difficult to manipulate. More...
06 Jun 2017
Image: A paper-based test strip could help people with heart failure know if their condition is worsening (Photo courtesy of the American Chemical Society).

Strip Test Enables Home Monitoring of Heart Condition

Heart failure can often be managed with medications and lifestyle changes, but its progression needs to be monitored closely to adjust treatment and prevent emergency room visits. Now scientists have developed a simple paper test strip that could potentially allow patients to monitor themselves for the first time. More...
05 Jun 2017
Image: Exhaled breath condensate is rapidly analyzed by a new graphene-based nanoelectronic sensor that detects nitrite, a key inflammatory marker in the inner lining of the respiratory airway (Photo courtesy of Azam Gholizadeh, Rutgers University).

Graphene-Based Sensor Helps Predict Asthma Attacks

Researchers have developed a prototype graphene-based device that detects inflammation in lungs, which could lead to earlier detection of asthma attacks and improve the management of asthma and other respiratory diseases, preventing hospitalizations and deaths. The invention helps pave the way for developing small wearable devices that could indicate when and at what dosage to take medication. More...
05 Jun 2017
Image: The T-Track CMV diagnostic ELISpot kit (Photo courtesy of Lophius Biosciences).

Assay Validated for CMV-Specific Immunity

Cytomegalovirus (CMV) is a major cause of infectious complications in immunocompromised individuals. Protection against CMV infection or reactivation is normally assured by both the innate and adaptive arms of the immune system. More...
30 May 2017

Untethered Proteins Could Help Diagnose MKD

Mevalonate Kinase Deficiency (MKD), also known as HIDS (hyper IgD syndrome), is a rare genetic condition that affects approximately 200 individuals worldwide. It is a spectrum of disease, with complications that range from mild to severe. MKD is one of more than 8,000 known rare and genetic conditions, which, although individually uncommon, collectively affect up to 10% of the population. More...
30 May 2017
Image: Microscopy image of the small intestine mucosa of a patient with active celiac disease (Photo courtesy of Ann-Christin Røberg Beitnes).

Novel Method Identifies Patients with Celiac Disease

Celiac disease is a T cell-mediated autoimmune disease triggered by the ingestion of gluten from wheat, rye and barley in genetically susceptible individuals. A gluten-free diet is the only current management for this disease. More...
24 May 2017
Image: The Cryptococcal Antigen Lateral Flow Assay (CrAg LFA) Immy test (Photo courtesy of Immuno-Mycologics).

Specificity Improved for Urinary Antigen Testing

The cryptococcal antigen lateral flow assay (CrAg LFA) Immy test is standardized for a fast screening point-of-care test for cryptococcosis, detecting cryptococcal antigen in serum and cerebrospinal fluid (CSF). More...
23 May 2017
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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