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Molecular Diagnostics

Image: The miRNeasy Serum/Plasma Kit: For purification of cell-free total RNA, including miRNA, from human plasma and serum (Photo courtesy of Qiagen)

Serum MicroRNA Panel Predict P-Tau/Aβ42 in CSF in Alzheimer's Disease

Amyloid β (Aβ) and tau pathologies are classic characteristic features of Alzheimer’s disease (AD), and they are widely used as diagnostic biomarkers. AD pathology is characterized by the accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the brain. More...
29 Nov 2021
Image: A comparison of monocyte and neutrophil phenotype in grade III and grade IV gliomas (Photo courtesy of Jayashree V. Raghavan)

Biomarkers Predict Disease Progression for Patients with Late-stage Brain Tumors

A team of Indian researchers has identified potential blood-based biomarkers that predict disease progression and survival times for patients with late-stage glioma-type brain tumors. More...
29 Nov 2021
Image: Atellica Solution (Photo courtesy of Siemens Healthineers)

Siemens Introduces New Intelligent, Integrated IVD Solutions Virtually at EUROMEDLAB 2021

Siemens Healthineers (Erlangen, Germany) introduced new intelligent, integrated IVD solutions virtually at the XXIV IFCCEFLM European Congress of Clinical Chemistry and Laboratory Medicine (EuroMedLab Congress 2021). More...
29 Nov 2021
Illustration

Blood and Saliva Samples Can Be Used to Detect Genetic Markers for Liver Cancer

Doctors examining the markers of liver cancer have found that the disease can be recognized by RNA fragments in saliva and blood. More...
29 Nov 2021
Image: Bone marrow smear from a person with myelodysplastic syndrome showing aberrant morphology and maturation (dysmyelopoiesis), resulting in ineffective blood cell production (Photo courtesy of Melbourne Blood Specialists)

Next-Generation Sequencing Impacts All Aspects of Myelodysplastic Syndrome Care

Myelodysplastic Syndrome (MDS) is a type of blood cancer that affects the bone marrow. It causes low levels of one or more types of blood cells in the blood. MDS is more common in people aged over 70, but it can happen at any age. More...
25 Nov 2021
Image: Absence of nuclear immunohistochemical staining of MSH2 protein (A) and presence of MLH1 protein (B) in urothelial cell carcinoma of the urinary bladder of a patient carrying a germline MSH2 mutation. Observe the nuclear staining in stromal cells as an internal control (Photo courtesy of Radboud University Nijmegen Medical Centre)

Simple Urine Test Detects Urothelial Cancers in Lynch Syndrome Patients

Lynch Syndrome (LS) is an inherited genetic disorder that carries a high risk of cancer. LS is caused by mutations affecting MLH1, MSH2, MSH6 or PMS2 genes. More than one in 300 people have LS but most do not know it and that is equivalent to more than 2,300 new cases every year in the UK. More...
24 Nov 2021
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Same Day DNA Sequencing-Based Test Identifies Secondary Infections in COVID-19 Patients

A same-day test has been shown to successfully identify secondary infections in COVID-19 patients in the intensive care unit (ICU) within hours rather than days. More...
23 Nov 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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