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Molecular Diagnostics

Nucleic acid amplification testing-based assay (NAT) improves the surveillance system and prevent transfusion-transmitted malaria in blood banks (Photo courtesy of University of Cambridge).

Blood Bank NAT-Based Assay Prevents Transfusion-Transmitted Malaria

Blood transfusion is an essential component of health care, which saves millions of lives across the world. The screening of blood donors for transfusion-transmissible agents is crucial in reducing risks of transfusion of infected units. More...
20 Aug 2020
Signatera assays are the first circulating tumor DNA (ctDNA) tests custom-built for each patient based on the unique mutations in an individual patient’s tumor (Photo courtesy of Natera Inc).

Circulating tumor DNA Test Predicts Immunotherapy Response

 Immunotherapy is a type of cancer treatment that helps the immune system fight cancer. Although some cancer patients derive dramatic and sustained benefit from immunotherapy, most cancer patients do not. More...
19 Aug 2020
The V-Plex Pro-inflammatory Panel 1 Human Kit (Photo courtesy of Meso Scale Diagnostics).

Lab Profiles Differentiate MIS-C From Severe Pediatric COVID-19

Initial reports from the Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) pandemic described children as being less susceptible to Coronavirus Disease 2019 (COVID-19) than adults. Subsequently, a severe and novel pediatric disorder termed Multisystem Inflammatory Syndrome in Children (MIS-C) emerged. More...
19 Aug 2020
Cells in wells of a 96 well-plate before (A) and after (B) lysis cell by Direct PCR (B1) and Chelex100 (B2) (Photo courtesy of University Hospital Hamburg‐Eppendorf).

Two Simple Methods Prepare DNA Suitable For Digital PCR

Although DNA of high quality can be easily prepared from cultured cells with commercially available kits, many studies involve a large number of samples which increases the cost drastically. More...
19 Aug 2020
Model of the HbA1c molecule (image courtesy of Biologic Models)

Elevated Glycolated Hemoglobin in Young People Predicts Likelihood of Diabetes or Cardiovascular Disease in Adulthood

A review of blood test results from more than 14,000 young people suggested that measurement of glycated hemoglobin (HbA1c) was a specific and useful nonfasting marker for identify high-risk youth who could benefit from lifestyle interventions to prevent diabetes and cardiovascular risk in adulthood. More...
19 Aug 2020
This photomicrograph of a Gram-stained urethral smear specimen, reveals some of the histopathology in an acute case of gonococcal urethritis, caused by the Gram-negative bacterium, Neisseria gonorrhoeae.  (Image courtesy of [U.S.] Centers for Disease Control and Prevention\'s Public Health Image Library)

Diagnostic Test Identifies Resistance Mutation that Enables Use of Inexpensive, Single Dose Gonorrhea Drug

By detecting the mutated gene responsible for resistance to the drug ciprofloxacin, it is possible to identify gonorrhea patients who can be cured by a single oral dose of this drug. More...
19 Aug 2020
Transmission electron microscope image of SARS-CoV-2 (2019-nCoV), the virus that causes COVID-19, isolated from a patient in the U.S.A. Virus particles are shown emerging from the surface of cells cultured in the laboratory. (Image courtesy of National Institute of Allergy and Infectious Diseases via Wikimedia Commons)

Panel of Five Serum Biomarkers Identifies COVID-19 Patients at High Risk to Develop Serious Complications

A recent paper suggested that elevated levels of five serum biomarkers could be used to identify COVID-19 patients who are at high risk for serious complications or death. More...
18 Aug 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.