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Molecular Diagnostics

Image: Transmission electron microscope image showing SARS-CoV-2, the virus that causes COVID-19. Virus particles are shown emerging from the surface of cells cultured in the laboratory (Photo courtesy of US NIAID, via Wikimedia Commons)

Liquid Biopsy Allows Monitoring of COVID-19 Damage to Cells, Tissues, and Organs

A recent study presented results that point to the utility of exploiting cell-free DNA as an analyte to monitor the damage caused to cells, tissues, and organs by COVID-19. More...
09 Feb 2021
Image: Photomicrograph of a moderately differentiated colorectal carcinoma with dirty necrosis (Photo courtesy of Mikael Häggström, MD).

Blood Test Detects Early Colorectal Adenomas

Colonoscopies are the gold standard for screening but have low compliance rates due to the invasiveness of the procedure. Stool-based tests have poor compliance and low sensitivity for advanced adenomas (AA), at about 24% to 42%. More...
08 Feb 2021
Image: Bone marrow aspirate showing acute myeloid leukemia (Photo courtesy of Wikipedia Commons)

Precise Measurement of DNA Length Polymorphisms Used to Diagnose Acute Myeloid Leukemia

By combining two powerful analytical tools, researchers have demonstrated the ability to diagnose diseases such as leukemia by quantifying both the size and proportion of DNA length polymorphisms. More...
08 Feb 2021
Image: The Natera Signatera Assay Can Predict Colon Cancer Relapse Months Earlier (Photo courtesy of Mohammed Haneefa Nizamud)

Liquid Biopsy Predicts Colon Cancer Relapse Months Earlier

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. More...
03 Feb 2021
Image: DNA fragments (yellow) derived from a transplanted heart alongside the patient’s own DNA (blue). A new blood test measures donor DNA fragments and detects acute heart transplant rejection earlier than current methods (Photo courtesy of Erina He, NIH Medical Arts)

Cell-Free DNA Detects Heart Allograft Acute Rejection

After heart transplantation, Endomyocardial biopsy (EMBx) is used to monitor for acute rejection (AR). Unfortunately, EMBx is invasive and its conventional histologic interpretation has limitations. More...
02 Feb 2021
Image: Structure of the CRMP1 protein (Photo courtesy of Wikimedia Commons)

AI-guided Immunoassay Measures Maternal Autoantibodies to Predict Likelihood of Autism Spectrum Disorder

An AI-guided immunoassay that measures maternal autoantibodies accurately predicts the likelihood that a child will develop autism spectrum disorder (ASD). More...
02 Feb 2021
Image: The 20-minute AI analysis detected prostate cancer in urine samples from 76 patients with greater than 99% accuracy (Photo courtesy of Korea Institute of Science and Technology)

A Rapid AI-based Screening Test for Prostate Cancer Biomarkers in Urine

A team of Korean investigators developed a highly accurate rapid technique for diagnosing prostate cancer based on AI (artificial intelligence) monitoring of urinary biomarkers. More...
01 Feb 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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