Molecular Diagnostics
Osteopontin Linked to Progressive Lung Scarring in Scleroderma Patients
Systemic sclerosis (SSc) is an autoimmune disease characterized by a distinct pathogenic triad of microvascular damage, dysregulation of innate and adaptive immunity, and fibrosis involving skin and many internal organs, such as the heart, kidney, and lungs. More...28 Dec 2020
Next-Generation Sequencing Detects Residual Disease in Acute Lymphoblastic Leukemia
The use of next-generation sequencing (NGS) to detect residual disease in acute lymphoblastic leukemia (ALL) patients after treatment can better gauge their risk of relapse and overall survival than multiparameter flow cytometry. More...24 Dec 2020
Distinct Mutation Patterns Identified in Appendiceal Cancer
The incidence of appendiceal cancer (AC) is rising, particularly among individuals younger than 50 years (early-onset AC), with unexplained etiologies. The unique spectrum of somatic cancer gene variations among patients with early-onset AC is largely undetermined. More...24 Dec 2020
Novel Classification System Identifies Prostate Cancer Patients Who May Benefit from Combined Immune and Radiation Therapies
A novel classification system is expected to aid in the subtyping of aggressive prostate cancers in patients who may benefit from combined immune and radiation therapies. More...22 Dec 2020
Plasma Levels of N-terminal Tau Fragments Predict Likelihood of Cognitive Decline in Elderly Individuals
A team of neurodegenerative disease researchers found that higher levels of N-terminal fragment of tau (NT1) in blood samples taken at the beginning of a survey of clinically normal elderly individuals were strongly associated with future risk of cognitive decline and progression to Alzheimer's disease. More...21 Dec 2020
Gene Expression Signature Traces Nonalcoholic Fatty Liver Disease Progression
Nonalcoholic fatty liver disease (NAFLD) is a common condition marked by the accumulation of triglycerides and other lipids in the liver and is associated with metabolic syndrome, type 2 diabetes, hypertension, and dyslipidemia. More...16 Dec 2020
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In Other News
Microtubule Binding Region of Tau Protein Is a Biomarker for Diagnosis of Alzheimer’s Disease
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Some Phosphorylated Tau Proteins Indicate Alzheimer’s Disease Prior to Appearance of Cognitive Impairment
Rare Variants Associated with Blood Pressure Regulation
Fast Antibacterial Susceptibility Testing by Measuring Electron Transfer Metabolism
Single-Cell Analysis Elucidates Mutation Patterns in Myeloid Malignancies
SARS-CoV-2 RNA Test Assessed Among Recovered COVID-19 Patients
Panel of Urinary Peptides Used to Diagnose Liver Fibrosis
Metagenomic Sequencing Quickly Identifies Pathogens in Body Fluids
Blood Biomarker Protein Correlates with Severity of Brain Damage in Stroke Patients
COVID-19 Lung Damage Caused by Persistence of Abnormal Cells
Levels of MicroRNAs in Saliva Are Diagnostic for Mild Traumatic Brain Injury
Methylated DNA Profiling Explored for Prenatal Testing Applications
CRP Tracking Predicts Potential Outcome for Hospitalized COVID-19 Patients
Blood Cell Mutations Underlie Severe Autoinflammatory Disease
A New Approach for Rapid Detection of Acute Kidney Injury in Children
Molecular Blood Test Kit Detects Gastric Cancer Early
A Breath-Analysis Test for Rapid Diagnosis of COVID-19
A Liquid Biopsy for Diagnosis of Pediatric High-Grade Glioma
Single-Cell Sequencing Reveals Clonal Diversity Among AML Patients
Artificial Enzyme Increases Sensitivity of Alzheimer's Disease Immunoassay
Genetic Alterations Associated with Sporadic Congenital Hydrocephalus
Sensitive Detection Method Identifies Protein Clumps in Parkinson’s Disease Skin Samples
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
