Molecular Diagnostics
Host Genetic, Environmental Factors Influence Urinary Tract Microbiome
The urinary microbiome is a relatively unexplored niche that varies with gender. Urinary microbes, especially in aging populations, are associated with morbidity. Both genetic and environmental factors influence the makeup of the urinary tract microbiome of older women. More...14 Aug 2020
Automated Malaria Diagnosis Enhanced by Deep Neural Networks
Plasmodium falciparum malaria remains one of the greatest global health burdens with over 228 million cases globally in 2018. In that year there were approximately 405,000 deaths due to malaria worldwide, with the African region accounting for 93% of these deaths, mostly among children. More...14 Aug 2020
Phosphorylated-Tau Blood Test Identifies Asymptomatic Alzheimer’s Disease
A blood test that determines circulating levels of the Alzheimer's disease (AD) biomarker protein phospho-tau217 (p-tau217) was found to distinguish AD from other neurodegenerative diseases, with significantly higher accuracy than established plasma- and MRI-based biomarkers, and its performance was not significantly different from key cerebral spinal fluid (CSF)- or PET-based measurements. More...10 Aug 2020
Somatic Evolution Identified in Non-Neoplastic IBD-Affected Colon
Inflammatory bowel disease (IBD) is a debilitating disease characterized by repeated flares of intestinal inflammation. The two major subtypes of IBD, Crohn’s disease (CD) and ulcerative colitis (UC) are distinguished by the location, continuity, and nature of the inflammatory lesions. More...06 Aug 2020
Elevated Angiotensin 1–7/Angiotensin II Ratio Predicts Favorable Outcomes in Patients with Heart Failure with Potential Link to COVID-19 Patients
A high ratio of angiotensin 1-7 to angiotensin II (Ang 1–7/Ang II ratio), was found to be an independent and incremental predictor of beneficial outcomes, higher survival rate, and decreased hospitalization duration for patients with heart failure and possibly in patients with cardiovascular complications due to COVID-19. More...04 Aug 2020
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In Other News
Nanostar Biosensors Use Raman Scattering for Direct Detection of Cancer-Related MicroRNAs
Pediatric Ependymoma Single-Cell Analysis Signatures Linked to Outcomes
Combined Proteomic/Genomic Method Detects Early Signs of Pancreatic Cancer
RNA Sequencing Identifies Novel Cell Class Linked to Rheumatoid Arthritis Flares
Plasma Lipidome Investigated in Hereditary Hemochromatosis
Circulating Tumor DNA Associated with Triple-Negative Breast Cancer Recurrence
CtDNA Assay for Cancer Recurrence, MRD Applications Demonstrated
COVID-19 Patients with Lymphocytopenia Are Likely to Suffer Severe Disease Symptoms
Blood Plasma Biomarker Linked to Middle Age Cognitive Decline
Immunogenomic Landscape of Hematological Malignancies Mapped
Elevated Levels of Two Protein Biomarkers Indicate Potential for Development of Pre-Eclampsia
Clonal Hematopoiesis of Indeterminate Potential Associated with hsC-Reactive Protein
Combined DNA/RNA Liquid Biopsy Test Identifies Genetic Aberrations in Metastatic Prostate Cancer
Gene Genomic Prostate Score Test Evaluated as Prognosis Predictor
Early-Onset Preeclampsia Risk Reflected in Circulating Maternal Transcripts
Rapid Genomic Profiling of Colon Cancers Improves Therapy Selection
Gut Microbiome Metabolomic Profiles Are Diagnostic for Liver Diseases
DNA Sequencing Technique Unravels Genetic Diversity of Cancer Tumors
An Eight MicroRNA Biomarker Panel for Diagnosis of ALS
RNA Sequencing as Alternative to Immunohistochemistry in Cancer Diagnostics
Blood Group Locus Contributes to COVID-19 Severity Risk
Precision Medicine-Based Genetic Testing Developed for Prostate Cancer
Sensitive and Accurate Cancer Detection Through Analysis of Circulating Free DNA Methylation Patterns
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.