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Molecular Diagnostics

Image: Histopathology of mucinous fibroplasia in prostate cancer (Photo courtesy of Cleveland Clinic)

African-Specific Molecular Taxonomy of Prostate Cancer Revealed

Prostate cancer is characterized by considerable geo-ethnic disparity. African ancestry is a significant risk factor for the disease, with 2.7-fold higher mortality rates across sub-Saharan Africa than global averages, yet the genetic and non-genetic factors underlying this is not known. More...
06 Sep 2022
Image: A simple blood test - administered before CAR-T cell treatment is initiated - may identify which patients are predisposed to developing neurotoxic side effects after CAR-T cell therapy. Severe side effects can include seizures, brain swelling, and strokes. Evidence of a stroke (red arrows) is seen on this MRI scan of the brain of a patient who developed neurotoxic side effects after CAR-T cell therapy (Photo courtesy of Dr. Omar Butt, Washington University School of Medicine)

Elevated Blood Levels of Neurofilament Light Chain Predict Likelihood of Neurotoxicity Following CAR-T Immunotherapy

An elevated level of neurofilament light chain (NfL) in the blood plasma can identify which patients are likely to develop neurotoxic side effects in the days and weeks following CAR-T cell therapy. More...
06 Sep 2022
Image: SkylineDx has announced the commercial launch of Merlin Assay as CE-IVD kit in Europe (Photo courtesy of Pexels)

qPCR Assay Identifies Melanoma Patients With Low-Risk Tumor That Could Avoid Invasive Biopsy

A new test can identify melanoma patients with low-risk tumor to help avoid sentinel lymph node biopsy, an invasive surgical procedure used to determine metastatic spread of the cancer for staging purposes. More...
06 Sep 2022
Image: Artist’s conception of amyotrophic lateral sclerosis (ALS) (Photo courtesy of www.123rf.com)

Improved ALS Blood Test Requires Less Stringent Storage and Work Conditions

Improvements to the method for isolating extracellular vesicles from the blood of amyotrophic lateral sclerosis (ALS) patients have yielded a more robust test for detection of the disorder that may be used under routine laboratory conditions. More...
05 Sep 2022
Image: Artificial intelligence could help narrow heart attack gender gap (Photo courtesy of Unsplash)

AI Algorithm Combined With Blood Test Quickly and Accurately Diagnoses Heart Attacks in Women

An algorithm developed using artificial intelligence (AI) could help doctors to diagnose heart attacks in women more accurately and quicker than ever before. More...
05 Sep 2022
Image: Extracellular vesicles (Photo courtesy of The [U.S.] National Institutes of Health)

EV-based Liquid Biopsy for the Diagnosis of Early-Stage Liver Cancer

An extracellular vesicle-based liquid biopsy method was shown to be a promising approach for the diagnosis of early-stage liver cancer. More...
03 Sep 2022
Image: Genomadix Cube is a fast, accurate, and portable molecular analyzer that uses the same PCR technology as a full service lab (Photo courtesy of Genomadix)

Fast, Accurate and Portable Molecular Analyzer to Revolutionize Diagnostics

Traditional lab-based tests can take days to weeks for results. Now, a fast, accurate, and portable DNA analyzer goes from sample to result in approximately an hour and delivers quality results outside of a lab. More...
03 Sep 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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