Molecular Diagnostics
Two Circulating Biomarkers Predict Cardiovascular Disease Risk in Psoriasis Patients
Blood levels of the protein biomarkers cardiac troponin I (cTnI) and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) in patients with psoriatic disease (PsD) were found to be associated with carotid plaque burden and the development of cardiovascular disease (CVD) independent of traditional CVD risk factors. More...11 Mar 2022
Fecal Microbiome Signature Predicts Pancreatic Cancer Risk
Researchers have identified a molecular signature of 27 microorganisms in stool samples that is able to predict whether an individual is at high risk of developing pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer. More...10 Mar 2022
Stem Cell Architecture Drives Myelodysplastic Syndrome Progression
Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells. Their findings, which could have significant benefits for patients with disease progression, were published today in Nature Medicine. More...10 Mar 2022
Single Test for Over 50 Genetic Diseases Cuts Diagnosis from Decades to Days
A single DNA test has been developed that can screen a patient's genome for over 50 genetic neurological and neuromuscular diseases such as Huntington's disease, muscular dystrophies and fragile X syndrome. The new test avoids a 'diagnostic odyssey' for patients that can take decades. The team has shown that the test is accurate. They are now working on validations to make it available in pathology labs. They expect it to be standard in global pathology labs within five years. More...09 Mar 2022
Paper-Based Portable Diagnostic Platform Accurately Detects Mosquito-Borne Diseases Under Field Conditions
Field trails conducted in Latin America have shown that a paper-based portable diagnostic platform could accurately detect patients with mosquito-borne diseases with sensitivities equivalent to laboratory PCR tests. More...09 Mar 2022
Low-Cost Multiplexed Electrochemical Biomarker Detection Platform to Be Commercialized in POC Diagnostics
A low-cost multiplexed electrochemical biomarker detection platform will be commercialized in point-of-care diagnostics to be put into the hands of patients and primary health practitioners. More...09 Mar 2022
Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases
Roughly one in every three children with a type of kidney cancer known as Wilms tumor, or nephroblastoma, carry germline alterations implicated in hereditary cancer risk, new research suggests — findings that have prompted more widespread genetic testing for Dutch children with the condition. More...08 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.