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Molecular Diagnostics

Image: A simple blood test - administered before CAR-T cell treatment is initiated - may identify which patients are predisposed to developing neurotoxic side effects after CAR-T cell therapy. Severe side effects can include seizures, brain swelling, and strokes. Evidence of a stroke (red arrows) is seen on this MRI scan of the brain of a patient who developed neurotoxic side effects after CAR-T cell therapy (Photo courtesy of Dr. Omar Butt, Washington University School of Medicine)

Elevated Blood Levels of Neurofilament Light Chain Predict Likelihood of Neurotoxicity Following CAR-T Immunotherapy

An elevated level of neurofilament light chain (NfL) in the blood plasma can identify which patients are likely to develop neurotoxic side effects in the days and weeks following CAR-T cell therapy. More...
06 Sep 2022
Image: SkylineDx has announced the commercial launch of Merlin Assay as CE-IVD kit in Europe (Photo courtesy of Pexels)

qPCR Assay Identifies Melanoma Patients With Low-Risk Tumor That Could Avoid Invasive Biopsy

A new test can identify melanoma patients with low-risk tumor to help avoid sentinel lymph node biopsy, an invasive surgical procedure used to determine metastatic spread of the cancer for staging purposes. More...
06 Sep 2022
Image: Artist’s conception of amyotrophic lateral sclerosis (ALS) (Photo courtesy of www.123rf.com)

Improved ALS Blood Test Requires Less Stringent Storage and Work Conditions

Improvements to the method for isolating extracellular vesicles from the blood of amyotrophic lateral sclerosis (ALS) patients have yielded a more robust test for detection of the disorder that may be used under routine laboratory conditions. More...
05 Sep 2022
Image: Artificial intelligence could help narrow heart attack gender gap (Photo courtesy of Unsplash)

AI Algorithm Combined With Blood Test Quickly and Accurately Diagnoses Heart Attacks in Women

An algorithm developed using artificial intelligence (AI) could help doctors to diagnose heart attacks in women more accurately and quicker than ever before. More...
05 Sep 2022
Image: Extracellular vesicles (Photo courtesy of The [U.S.] National Institutes of Health)

EV-based Liquid Biopsy for the Diagnosis of Early-Stage Liver Cancer

An extracellular vesicle-based liquid biopsy method was shown to be a promising approach for the diagnosis of early-stage liver cancer. More...
03 Sep 2022
Image: Genomadix Cube is a fast, accurate, and portable molecular analyzer that uses the same PCR technology as a full service lab (Photo courtesy of Genomadix)

Fast, Accurate and Portable Molecular Analyzer to Revolutionize Diagnostics

Traditional lab-based tests can take days to weeks for results. Now, a fast, accurate, and portable DNA analyzer goes from sample to result in approximately an hour and delivers quality results outside of a lab. More...
03 Sep 2022
Image: CT 3D surface rendering of the lungs and heart from a patient with pulmonary arterial hypertension (Photo courtesy of NIH)

First-of-Its-Kind Blood Test Evaluates Severity and Predicts Survivability in Rare Lung Disease

A novel blood test can easily evaluate disease severity and predict survivability in patients with pulmonary arterial hypertension (PAH), a rare, life-threatening condition that causes unexplained high blood pressure in the lungs. More...
02 Sep 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.